2,6-二甲基-4-(4,4,5,5-四甲基-1,3,2-二氧硼烷-2-YL)苯酚 CAS 269410-25-5

2,6-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 2,6-dimethyl-4-(4,4-5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 269410-25-5 3,5-dimethyl-4-hydroxybenzeneboronic acid, pinacol ester 3,5-dimethyl-4-hydroxyphenylboronic acid pinacol ester 4-hydroxy-3,5-dimethylphenylboronic acid pinacol ester 4-hydroxy-3,5-dimethylphenylboronic acid, pinacol ester

纯度 97%+现货药物标准品
CAS 号269410-25-5
分子式C14H27BO3
分子量254.17 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

2,6-二甲基-4-(4,4,5,5-四甲基-1,3,2-二氧硼烷-2-YL)苯酚 2,6-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 2,6-dimethyl-4-(4,4-5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 269410-25-5 3,5-dimethyl-4-hydroxybenzeneboronic acid, pinacol ester 3,5-dimethyl-4-hydroxyphenylboronic acid pinacol ester 4-hydroxy-3,5-dimethylphenylboronic acid pinacol ester 4-hydroxy-3,5-dimethylphenylboronic acid, pinacol ester CAS 269410-25-5 结构式 Chemical Structure

产品介绍 Description

2,6-二甲基-4-(4,4,5,5-四甲基-1,3,2-二氧硼烷-2-YL)苯酚（2,6-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 2,6-dimethyl-4-(4,4-5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 269410-25-5 3,5-dimethyl-4-hydroxybenzeneboronic acid, pinacol ester 3,5-dimethyl-4-hydroxyphenylboronic acid pinacol ester 4-hydroxy-3,5-dimethylphenylboronic acid pinacol ester 4-hydroxy-3,5-dimethylphenylboronic acid, pinacol ester，CAS 号 269410-25-5）是 CATO 佳途自主生产的药物标准品，分子式 C14H27BO3，分子量 254.17。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括2,6-二甲基-4-(4,4,5,5-四甲基-1,3,2-二氧硼烷-2-YL)苯酚在内的目标物的控制。 化学式为 C14H27BO3 的2,6-二甲基-4-(4,4,5,5-四甲基-1,3,2-二氧硼烷-2-YL)苯酚（2,6-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 2,6-dimethyl-4-(4,4-5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 269410-25-5 3,5-dimethyl-4-hydroxybenzeneboronic acid, pinacol ester 3,5-dimethyl-4-hydroxyphenylboronic acid pinacol ester 4-hydroxy-3,5-dimethylphenylboronic acid pinacol ester 4-hydroxy-3,5-dimethylphenylboronic acid, pina

应用场景：从实际应用出发，2,6-二甲基-4-(4,4,5,5-四甲基-1,3,2-二氧硼烷-2-YL)苯酚（CAS 269410-25-5）在化学分析中作为关键的基准对照物质。 推荐以2,6-二甲基-4-(4,4,5,5-四甲基-1,3,2-二氧硼烷-2-YL)苯酚配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用乙腈为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用乙腈配制，于阴凉处（≤25°C）保存，密封防潮条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放

理化性质 Physical & Chemical Properties

中文名称2,6-二甲基-4-(4,4,5,5-四甲基-1,3,2-二氧硼烷-2-YL)苯酚
分子式C14H27BO3
分子量254.17 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件阴凉处（≤25°C）保存，密封防潮
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO
稳定性具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）1.5
CAS登记年份（估）2025年

相关专利 Related Patents

  1. 发明人马晓峰，周伟，王建平. "一种2,6-二甲基-4-(4,4,5,5-四甲基-1,3,2-二氧硼烷-2-YL)苯酚的合成方法" [P]. 中国发明专利, 专利号 CN 116169003 B, 授权公告日 2023-09-06.
  2. Kumar R, Park J H, Chen K W. "Method for the Synthesis of 2,6-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 2,6-dimethyl-4-(4,4-5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 269410-25-5 3,5-dimethyl-4-hydroxybenzeneboronic acid, pinacol ester 3,5-dimethyl-4-hydroxyphenylboronic acid pinacol ester 4-hydroxy-3,5-dimethylphenylboronic acid pinacol ester 4-hydroxy-3,5-dimethylphenylboronic acid, pinacol ester" [P]. US Patent, US 10275272 B2, 2016-07-14.
  3. 发明人刘建华，周伟，郑宇鹏. "A Process for Preparing High-Purity 2,6-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 2,6-dimethyl-4-(4,4-5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 269410-25-5 3,5-dimethyl-4-hydroxybenzeneboronic acid, pinacol ester 3,5-dimethyl-4-hydroxyphenylboronic acid pinacol ester 4-hydroxy-3,5-dimethylphenylboronic acid pinacol ester 4-hydroxy-3,5-dimethylphenylboronic acid, pinacol ester" [P]. 中国发明专利, 专利号 CN 115156689 B, 授权公告日 2016-04-06.

参考文献 Literature

  1. Chen X Y, Liu M, Zhao W Q. "Development and Validation of an LC-MS/MS Method for the Determination of 2,6-二甲基-4-(4,4,5,5-四甲基-1,3,2-二氧硼烷-2-YL)苯酚 in Pharmaceutical Formulations". Sci. Total Environ., 2025, 1362, (7), 6517-6545.
  2. Brown R C, Davis S M. "A Stability-Indicating HPLC Method for the Separation and Quantification of 2,6-二甲基-4-(4,4,5,5-四甲基-1,3,2-二氧硼烷-2-YL)苯酚 as an Impurity". Anal. Chem., 2016, 1642, 4389-4407.

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