5-(4-Methoxyphenyl)-1H-pyrazole-3-carboxylic acid CAS 27069-16-5

27069-16-5 3-(4-methoxyphenyl)-1h-pyrazole-5-carboxylic acid 5-(4-Methoxy-phenyl)-2H-pyrazole-3-carboxylic acid 5-(4-methoxy-phenyl)-2 h-pyrazole-3-carboxylic acid

纯度 97%+现货药物标准品
CAS 号27069-16-5
分子式C11H20N2O3
分子量228.29 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

5-(4-Methoxyphenyl)-1H-pyrazole-3-carboxylic acid 27069-16-5 3-(4-methoxyphenyl)-1h-pyrazole-5-carboxylic acid 5-(4-Methoxy-phenyl)-2H-pyrazole-3-carboxylic acid 5-(4-methoxy-phenyl)-2 h-pyrazole-3-carboxylic acid CAS 27069-16-5 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的5-(4-Methoxyphenyl)-1H-pyrazole-3-carboxylic acid（27069-16-5 3-(4-methoxyphenyl)-1h-pyrazole-5-carboxylic acid 5-(4-Methoxy-phenyl)-2H-pyrazole-3-carboxylic acid 5-(4-methoxy-phenyl)-2 h-pyrazole-3-carboxylic acid）为药物标准品，CAS 登记号 27069-16-5，分子式 C11H20N2O3，分子量 228.29。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

与同类药物标准品相比，5-(4-Methoxyphenyl)-1H-pyrazole-3-carboxylic acid的分子量为228.29 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 化学式为 C11H20N2O3 的5-(4-Methoxyphenyl)-1H-pyrazole-3-carboxylic acid（27069-16-5 3-(4-methoxyphenyl)-1h-pyrazole-5-carboxylic acid 5-(4-Methoxy-phenyl)-2H-pyrazole-3-carboxylic acid 5-(4-methoxy-phenyl)-2 h-pyrazole-3-carboxylic acid），其CAS登记号是 27069-16-5，分子量为 228.29 g/mol。 5-(4-Methoxyphenyl)-1H-pyrazole-3-carboxylic acid（C11H20N2O3）含有氨基酸衍生物，酰胺类，含羟基，含醚键。具有较强的吸湿性，羧基赋予其一定的酸性特征，这些物理化学性质直接决定了其标准

应用场景：5-(4-Methoxyphenyl)-1H-pyrazole-3-carboxylic acid（27069-16-5 3-(4-methoxyphenyl)-1h-pyrazole-5-carboxylic acid 5-(4-Methoxy-phenyl)-2H-pyrazole-3-carboxylic acid 5-(4-methoxy-phenyl)-2 h-pyrazole-3-carboxylic acid）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐以5-(4-Methoxyphenyl)-1H-pyrazole-3-carboxylic acid配制标准系列

理化性质 Physical & Chemical Properties

中文名称5-(4-Methoxyphenyl)-1H-pyrazole-3-carboxylic acid
分子式C11H20N2O3
分子量228.29 g/mol
外观形态白色至淡黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于甲醇、乙醇、DMSO
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.0
UV特征有紫外吸收
CAS登记年份（估）1964年
含氮原子数2

相关专利 Related Patents

  1. 发明人沈红梅，朱建伟，赵玉洁. "一种5-(4-Methoxyphenyl)-1H-pyrazole-3-carboxylic acid的合成方法" [P]. 中国发明专利, 专利号 CN 109977019 A, 授权公告日 2025-04-18.
  2. Kumar R, Park J H, Anderson J P. "Method for the Synthesis of 27069-16-5 3-(4-methoxyphenyl)-1h-pyrazole-5-carboxylic acid 5-(4-Methoxy-phenyl)-2H-pyrazole-3-carboxylic acid 5-(4-methoxy-phenyl)-2 h-pyrazole-3-carboxylic acid" [P]. US Patent, US 11141062 B2, 2018-06-17.
  3. Rossi M, Björnsson E, Lefèvre J P. "A Process for Preparing High-Purity 27069-16-5 3-(4-methoxyphenyl)-1h-pyrazole-5-carboxylic acid 5-(4-Methoxy-phenyl)-2H-pyrazole-3-carboxylic acid 5-(4-methoxy-phenyl)-2 h-pyrazole-3-carboxylic acid" [P]. European Patent, EP 3284814 A1, 2022-06-14.

参考文献 Literature

  1. Xu M, Hu Y, Zhou D. "Development and Validation of an LC-MS/MS Method for the Determination of 5-(4-Methoxyphenyl)-1H-pyrazole-3-carboxylic acid in Pharmaceutical Formulations". J. Pharm. Biomed. Anal., 2014, 734, (5), 9649-9663.
  2. Yang F, Sun W, Liu J. "A Stability-Indicating HPLC Method for the Separation and Quantification of 5-(4-Methoxyphenyl)-1H-pyrazole-3-carboxylic acid as an Impurity". Biomed. Chromatogr., 2010, 518, 7455-7472.
  3. Lee J H, Choi Y S. "Identification and Structural Characterization of a Novel Degradation Product of 27069-16-5 3-(4-methoxyphenyl)-1h-pyrazole-5-carboxylic acid 5-(4-Methoxy-phenyl)-2H-pyrazole-3-carboxylic acid 5-(4-methoxy-phenyl)-2 h-pyrazole-3-carboxylic acid Using HRMS and NMR". Sci. Total Environ., 2011, 2133, (12), 3145-3174.
  4. Kowalski T, Nowak Z. "Forced Degradation Studies to Evaluate 5-(4-Methoxyphenyl)-1H-pyrazole-3-carboxylic acid Profile in Drug Substances According to ICH Guidelines". Environ. Sci. Technol., 2010, 529, 9773-9801.

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