3-脱氧-2-酮-6-磷酸葡萄糖酸 锂盐 CAS 27244-54-8

2-dehydro-3-deoxy-D-gluconate 6-phosphate 27244-54-8 2-keto-3-deoxy-6-phospho-D-gluconate 2-dehydro-3-deoxy-6-phospho-D-gluconate 2-keto-3-deoxy-6-phospho-gluconate 6-phospho-2-dehydro-3-deoxy-D-gluconate 2-keto-3-deoxy-6-phosphogluconate 2-keto-3-deoxy-6-P-gluconate 6-p-2-k-3-deo-gluconate 6-phospho-2-keto-3-deoxygluconate 6-phospho-2-dehydro-3-deoxygluconate 2-keto-3-deoxygluconate-6-P 3-deoxy-D-erythro-hex-2-ulosonic acid 6-phosphate 3-deoxy-D-erythro-hex-2-ulosonate-6-phosphate KDPG

纯度 97%+现货药物标准品
CAS 号27244-54-8
分子式C6H8O9P
分子量255.10 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

3-脱氧-2-酮-6-磷酸葡萄糖酸 锂盐 2-dehydro-3-deoxy-D-gluconate 6-phosphate 27244-54-8 2-keto-3-deoxy-6-phospho-D-gluconate 2-dehydro-3-deoxy-6-phospho-D-gluconate 2-keto-3-deoxy-6-phospho-gluconate 6-phospho-2-dehydro-3-deoxy-D-gluconate 2-keto-3-deoxy-6-phosphogluconate 2-keto-3-deoxy-6-P-gluconate 6-p-2-k-3-deo-gluconate 6-phospho-2-keto-3-deoxygluconate 6-phospho-2-dehydro-3-deoxygluconate 2-keto-3-deoxygluconate-6-P 3-deoxy-D-erythro-hex-2-ulosonic acid 6-phosphate 3-deoxy-D-erythro-hex-2-ulosonate-6-phosphate KDPG CAS 27244-54-8 结构式 Chemical Structure

产品介绍 Description

CAS 27244-54-8 对应的3-脱氧-2-酮-6-磷酸葡萄糖酸 锂盐（2-dehydro-3-deoxy-D-gluconate 6-phosphate 27244-54-8 2-keto-3-deoxy-6-phospho-D-gluconate 2-dehydro-3-deoxy-6-phospho-D-gluconate 2-keto-3-deoxy-6-phospho-gluconate 6-phospho-2-dehydro-3-deoxy-D-gluconate 2-keto-3-deoxy-6-phosphogluconate 2-keto-3-deoxy-6-P-gluconate 6-p-2-k-3-deo-gluconate 6-phospho-2-keto-3-deoxygluconate 6-phospho-2-dehydro-3-deoxygluconate 2-keto-3-deoxygluconate-6-P 3-deoxy-D-erythro-hex-2-ulosonic acid 6-phosphate 3-deoxy-D-erythro-hex-2-ulosonate-6-phosphate KDPG）为 CATO 佳途药物标准品产品线成员。分子式 C6H8O9P，分子量 255.10。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

受分子结构中糖类衍生物，含磷酸酯基的影响，3-脱氧-2-酮-6-磷酸葡萄糖酸 锂盐表现为白色至类白色结晶性粉末。其固体形态的物理化学属性——包括255.10 g/mol的分子量——对于选择合适的样品前处理方法和分析技术具有指导意义。分子中包含芳环或共轭体系，在UV-Vis光谱中具有特征性吸收带，适用于紫外或二极管阵列检测器（DAD）的定量分析。 3-脱氧-2-酮-6-磷酸葡萄糖酸 锂盐（2-dehydro-3-deoxy-D-gluconate 6-phosphate 27244-54-8 2-keto-3-deoxy-6-phospho-D-gluconate 2-dehydro-3-deoxy-6-phospho-D-gluconate 2-keto-3-deoxy-6-phospho-gluconate 6-phospho-2-dehydro-3-deoxy-D-gluconate 2-keto-3-deoxy-6-phosphogluconate 2-keto-3-deoxy-6-P-gluconate 6-p-2-k-3-deo-gluconate 6-phospho-2-

应用场景：3-脱氧-2-酮-6-磷酸葡萄糖酸 锂盐（2-dehydro-3-deoxy-D-gluconate 6-phosphate 27244-54-8 2-keto-3-deoxy-6-phospho-D-gluconate 2-dehydro-3-deoxy-6-phospho-D-gluconate 2-keto-3-deoxy-6-phospho-gluconate 6-phospho-2-dehydro-3-deoxy-D-gluconate 2-keto-3-deoxy-6-phosphogluconate 2-keto-3-deoxy-6-P-gluconate 6-p-2-k-3-d

理化性质 Physical & Chemical Properties

中文名称3-脱氧-2-酮-6-磷酸葡萄糖酸 锂盐
分子式C6H8O9P
分子量255.10 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件阴凉处（≤25°C）保存，密封防潮
溶解性参考可溶于甲醇、乙醇、DMSO、水
稳定性空气中长期暴露可能发生缓慢氧化；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.0
UV特征有紫外吸收
CAS登记年份（估）1964年

相关专利 Related Patents

  1. Lefèvre J P, Martínez F, Schröder R. "一种3-脱氧-2-酮-6-磷酸葡萄糖酸 锂盐的合成方法" [P]. European Patent, EP 3924006 A1, 2015-05-15.
  2. 发明人高志强，周伟，冯建国. "Method for the Synthesis of 2-dehydro-3-deoxy-D-gluconate 6-phosphate 27244-54-8 2-keto-3-deoxy-6-phospho-D-gluconate 2-dehydro-3-deoxy-6-phospho-D-gluconate 2-keto-3-deoxy-6-phospho-gluconate 6-phospho-2-dehydro-3-deoxy-D-gluconate 2-keto-3-deoxy-6-phosphogluconate 2-keto-3-deoxy-6-P-gluconate 6-p-2-k-3-deo-gluconate 6-phospho-2-keto-3-deoxygluconate 6-phospho-2-dehydro-3-deoxygluconate 2-keto-3-deoxygluconate-6-P 3-deoxy-D-erythro-hex-2-ulosonic acid 6-phosphate 3-deoxy-D-erythro-hex-2-ulosonate-6-phosphate KDPG" [P]. 中国发明专利, 专利号 CN 109301848 A, 授权公告日 2021-08-25.

参考文献 Literature

  1. Zhang Y, Li Q, Chen T. "Development and Validation of an LC-MS/MS Method for the Determination of 3-脱氧-2-酮-6-磷酸葡萄糖酸 锂盐 in Pharmaceutical Formulations". Sci. Total Environ., 2018, 1974, (9), 7248-7266.
  2. Yamamoto K, Tanaka H, Suzuki T. "A Stability-Indicating HPLC Method for the Separation and Quantification of 3-脱氧-2-酮-6-磷酸葡萄糖酸 锂盐 as an Impurity". J. Sep. Sci., 2018, 1571, (7), 9740-9768.
  3. Wang L, Li J, Zhang H. "Identification and Structural Characterization of a Novel Degradation Product of 2-dehydro-3-deoxy-D-gluconate 6-phosphate 27244-54-8 2-keto-3-deoxy-6-phospho-D-gluconate 2-dehydro-3-deoxy-6-phospho-D-gluconate 2-keto-3-deoxy-6-phospho-gluconate 6-phospho-2-dehydro-3-deoxy-D-gluconate 2-keto-3-deoxy-6-phosphogluconate 2-keto-3-deoxy-6-P-gluconate 6-p-2-k-3-deo-gluconate 6-phospho-2-keto-3-deoxygluconate 6-phospho-2-dehydro-3-deoxygluconate 2-keto-3-deoxygluconate-6-P 3-deoxy-D-erythro-hex-2-ulosonic acid 6-phosphate 3-deoxy-D-erythro-hex-2-ulosonate-6-phosphate KDPG Using HRMS and NMR". J. Chromatogr. A, 2019, 512, (9), 4865-4874.

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