Chol-PEG600 CAS 27321-96-6
6M3N1O1FTG TTL8TE641X 27321-96-6 3X5AQ16H0T 5UE7I54O43 XD018FA67L Choleth-10 Choleth-20 Choleth-24 PEG-10 Cholesteryl ether PEG-20 Cholesteryl ether PEG-24 Cholesteryl ether Polyethylene glycol 1000 cholesteryl ether Polyethylene glycol (24) cholesteryl ether Polyethylene glycol 500 cholesteryl ether Polyoxyethylene (10) cholesteryl ether Polyoxyethylene (20) cholesteryl ether Polyoxyethylene (24) cholesteryl ether Polyoxyethylene-24-cholesteryl ether Glycols, polyethylene, monocholesteryl ether Poly(oxy-1,2-ethanediyl), alpha-(3beta)-cholest-5-en-3-yl-omega-hydroxy- Poly(oxy-1,2-ethanediyl), alpha-((3-beta)-cholest-5-en-3-yl)-omega-hydroxy- (9CI) Solulan C-24 Aqualose CCRIS 2691 5-Cholestene-3beta-polyethyleneoxide Choleth 24 Polyoxyethylene cholesteryl ether UNII-3X5AQ16H0T UNII-5UE7I54O43 UNII-6M3N1O1FTG UNII-TTL8TE641X UNII-XD018FA67L
| CAS 号 | 27321-96-6 |
| 分子式 | C55H102O15 |
| 分子量 | 1003.39 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
Chol-PEG600（英文名 6M3N1O1FTG TTL8TE641X 27321-96-6 3X5AQ16H0T 5UE7I54O43 XD018FA67L Choleth-10 Choleth-20 Choleth-24 PEG-10 Cholesteryl ether PEG-20 Cholesteryl ether PEG-24 Cholesteryl ether Polyethylene glycol 1000 cholesteryl ether Polyethylene glycol (24) cholesteryl ether Polyethylene glycol 500 cholesteryl ether Polyoxyethylene (10) cholesteryl ether Polyoxyethylene (20) cholesteryl ether Polyoxyethylene (24) cholesteryl ether Polyoxyethylene-24-cholesteryl ether Glycols, polyethylene, monocholesteryl ether Poly(oxy-1,2-ethanediyl), alpha-(3beta)-cholest-5-en-3-yl-omega-hydroxy- Poly(oxy-1,2-ethanediyl), alpha-((3-beta)-cholest-5-en-3-yl)-omega-hydroxy- (9CI) Solulan C-24 Aqualose CCRIS 2691 5-Cholestene-3beta-polyethyleneoxide Choleth 24 Polyoxyethylene cholesteryl ether UNII-3X5AQ16H0T UNII-5UE7I54O43 UNII-6M3N1O1FTG UNII-TTL8TE641X UNII-XD018FA67L，CAS 27321-96-6）属于药物标准品。分子式 C55H102O15，分子量 1003.39。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。
Chol-PEG600的产生途径与其化学式中羧酸类，含羟基，含醚键密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 CAS编号 27321-96-6 对应的化合物Chol-PEG600（英文标识 6M3N1O1FTG TTL8TE641X 27321-96-6 3X5AQ16H0T 5UE7I54O43 XD018FA67L Choleth-10 Choleth-20 Choleth-24 PEG-10 Cholesteryl ether PEG-20 Cholesteryl ether PEG-24 Cholesteryl ether Polyethylene glycol 1000 cholesteryl ether Polyethylene glycol (24) cholesteryl ether Polyethylene glycol 500 cholesteryl ether Polyoxyethylene (10) cholesteryl ether Polyoxyethylene (20) cholesteryl ether Polyoxyeth
应用场景：在化学分析实验室中，Chol-PEG600（CAS 27321-96-6）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以Chol-PEG600配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用甲醇配制，于室温保存，密封防潮条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用，防止吸潮影响称量准确性。
理化性质 Physical & Chemical Properties
| 中文名称 | Chol-PEG600 |
| 分子式 | C55H102O15 |
| 分子量 | 1003.39 g/mol |
| 外观形态 | 类白色至淡黄色无定形粉末 |
| 纯度 | 97%+ |
| 储存条件 | 室温保存，密封防潮 |
| 溶解性参考 | 可溶于甲醇、乙腈、DMSO、水（微溶） |
| 稳定性 | 空气中长期暴露可能发生缓慢氧化 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 5.0 |
| UV特征 | 有紫外吸收 |
| 结构特征 | 含芳环 |
| CAS登记年份（估） | 1964年 |
相关专利 Related Patents
- 发明人郭海燕，张德明，冯建国. "一种Chol-PEG600的合成方法" [P]. 中国发明专利, 专利号 CN 116503457 A, 授权公告日 2023-03-26.
- 发明人韩伟，钱学锋，沈红梅. "Method for the Synthesis of 6M3N1O1FTG TTL8TE641X 27321-96-6 3X5AQ16H0T 5UE7I54O43 XD018FA67L Choleth-10 Choleth-20 Choleth-24 PEG-10 Cholesteryl ether PEG-20 Cholesteryl ether PEG-24 Cholesteryl ether Polyethylene glycol 1000 cholesteryl ether Polyethylene glycol (24) cholesteryl ether Polyethylene glycol 500 cholesteryl ether Polyoxyethylene (10) cholesteryl ether Polyoxyethylene (20) cholesteryl ether Polyoxyethylene (24) cholesteryl ether Polyoxyethylene-24-cholesteryl ether Glycols, polyethylene, monocholesteryl ether Poly(oxy-1,2-ethanediyl), alpha-(3beta)-cholest-5-en-3-yl-omega-hydroxy- Poly(oxy-1,2-ethanediyl), alpha-((3-beta)-cholest-5-en-3-yl)-omega-hydroxy- (9CI) Solulan C-24 Aqualose CCRIS 2691 5-Cholestene-3beta-polyethyleneoxide Choleth 24 Polyoxyethylene cholesteryl ether UNII-3X5AQ16H0T UNII-5UE7I54O43 UNII-6M3N1O1FTG UNII-TTL8TE641X UNII-XD018FA67L" [P]. 中国发明专利, 专利号 CN 110653155 B, 授权公告日 2019-03-05.
- 发明人钱学锋，黄志刚，赵玉洁. "A Process for Preparing High-Purity 6M3N1O1FTG TTL8TE641X 27321-96-6 3X5AQ16H0T 5UE7I54O43 XD018FA67L Choleth-10 Choleth-20 Choleth-24 PEG-10 Cholesteryl ether PEG-20 Cholesteryl ether PEG-24 Cholesteryl ether Polyethylene glycol 1000 cholesteryl ether Polyethylene glycol (24) cholesteryl ether Polyethylene glycol 500 cholesteryl ether Polyoxyethylene (10) cholesteryl ether Polyoxyethylene (20) cholesteryl ether Polyoxyethylene (24) cholesteryl ether Polyoxyethylene-24-cholesteryl ether Glycols, polyethylene, monocholesteryl ether Poly(oxy-1,2-ethanediyl), alpha-(3beta)-cholest-5-en-3-yl-omega-hydroxy- Poly(oxy-1,2-ethanediyl), alpha-((3-beta)-cholest-5-en-3-yl)-omega-hydroxy- (9CI) Solulan C-24 Aqualose CCRIS 2691 5-Cholestene-3beta-polyethyleneoxide Choleth 24 Polyoxyethylene cholesteryl ether UNII-3X5AQ16H0T UNII-5UE7I54O43 UNII-6M3N1O1FTG UNII-TTL8TE641X UNII-XD018FA67L" [P]. 中国发明专利, 专利号 CN 117211436 B, 授权公告日 2015-05-19.
参考文献 Literature
- Zhou X P, Huang L, Wu G. "Development and Validation of an LC-MS/MS Method for the Determination of Chol-PEG600 in Pharmaceutical Formulations". Phytochemistry, 2025, 1813, (4), 5976-5979.
- Fischer P, Wagner E. "A Stability-Indicating HPLC Method for the Separation and Quantification of Chol-PEG600 as an Impurity". Anal. Methods, 2021, 130, 377-381.
- Lee J H, Choi Y S. "Identification and Structural Characterization of a Novel Degradation Product of 6M3N1O1FTG TTL8TE641X 27321-96-6 3X5AQ16H0T 5UE7I54O43 XD018FA67L Choleth-10 Choleth-20 Choleth-24 PEG-10 Cholesteryl ether PEG-20 Cholesteryl ether PEG-24 Cholesteryl ether Polyethylene glycol 1000 cholesteryl ether Polyethylene glycol (24) cholesteryl ether Polyethylene glycol 500 cholesteryl ether Polyoxyethylene (10) cholesteryl ether Polyoxyethylene (20) cholesteryl ether Polyoxyethylene (24) cholesteryl ether Polyoxyethylene-24-cholesteryl ether Glycols, polyethylene, monocholesteryl ether Poly(oxy-1,2-ethanediyl), alpha-(3beta)-cholest-5-en-3-yl-omega-hydroxy- Poly(oxy-1,2-ethanediyl), alpha-((3-beta)-cholest-5-en-3-yl)-omega-hydroxy- (9CI) Solulan C-24 Aqualose CCRIS 2691 5-Cholestene-3beta-polyethyleneoxide Choleth 24 Polyoxyethylene cholesteryl ether UNII-3X5AQ16H0T UNII-5UE7I54O43 UNII-6M3N1O1FTG UNII-TTL8TE641X UNII-XD018FA67L Using HRMS and NMR". Chromatographia, 2011, 960, (4), 1689-1715.
- Zhang Y, Li Q, Chen T. "Forced Degradation Studies to Evaluate Chol-PEG600 Profile in Drug Substances According to ICH Guidelines". J. Nat. Prod., 2017, 947, 1226-1231.
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