4,4′-亚甲基二(<I>N</I>,<I>N</I>-二缩水甘油基苯胺) CAS 28768-32-3

28768-32-3 2I8ZB2RX2U Tetraglycidyl-4,4'-methylene dianiline 4,4'-Methylenebis(N,N-bis(2,3-epoxypropyl)aniline) 2-Oxiranemethanamine, N,N'-(methylenedi-4,1-phenylene)bis(N-(2-oxiranylmethyl)- Oxiranemethanamine, N,N'-(methylenedi-4,1-phenylene)bis(N-(oxiranylmethyl)- EINECS 249-204-3 4,4'-Methylenebis(diglycidyl aniline) UNII-2I8ZB2RX2U EC 249-204-3

纯度 97%+现货药物标准品
CAS 号28768-32-3
分子式C25H42N2O4
分子量434.61 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

4,4′-亚甲基二(<I>N</I>,<I>N</I>-二缩水甘油基苯胺) 28768-32-3 2I8ZB2RX2U Tetraglycidyl-4,4'-methylene dianiline 4,4'-Methylenebis(N,N-bis(2,3-epoxypropyl)aniline) 2-Oxiranemethanamine, N,N'-(methylenedi-4,1-phenylene)bis(N-(2-oxiranylmethyl)- Oxiranemethanamine, N,N'-(methylenedi-4,1-phenylene)bis(N-(oxiranylmethyl)- EINECS 249-204-3 4,4'-Methylenebis(diglycidyl aniline) UNII-2I8ZB2RX2U EC 249-204-3 CAS 28768-32-3 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的4,4′-亚甲基二(<I>N</I>,<I>N</I>-二缩水甘油基苯胺)（28768-32-3 2I8ZB2RX2U Tetraglycidyl-4,4'-methylene dianiline 4,4'-Methylenebis(N,N-bis(2,3-epoxypropyl)aniline) 2-Oxiranemethanamine, N,N'-(methylenedi-4,1-phenylene)bis(N-(2-oxiranylmethyl)- Oxiranemethanamine, N,N'-(methylenedi-4,1-phenylene)bis(N-(oxiranylmethyl)- EINECS 249-204-3 4,4'-Methylenebis(diglycidyl aniline) UNII-2I8ZB2RX2U EC 249-204-3）为药物标准品，CAS 登记号 28768-32-3，分子式 C25H42N2O4，分子量 434.61。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

与同类药物标准品相比，4,4′-亚甲基二(<I>N</I>,<I>N</I>-二缩水甘油基苯胺)的分子量为434.61 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 化学式为 C25H42N2O4 的4,4′-亚甲基二(<I>N</I>,<I>N</I>-二缩水甘油基苯胺)（28768-32-3 2I8ZB2RX2U Tetraglycidyl-4,4'-methylene dianiline 4,4'-Methylenebis(N,N-bis(2,3-epoxypropyl)aniline) 2-Oxiranemethanamine, N,N'-(methylenedi-4,1-phenylene)bis(N-(2-oxiranylmethyl)- Oxiranemethanamine, N,N'-(methylenedi-4,1-phenylene)bis(N-(oxiranylmethyl)- EINECS 249-204-3 4,4'-Methylenebis(diglycidyl aniline) UNII-2I8ZB2RX2U EC 249-204

应用场景：4,4′-亚甲基二(<I>N</I>,<I>N</I>-二缩水甘油基苯胺)（28768-32-3 2I8ZB2RX2U Tetraglycidyl-4,4'-methylene dianiline 4,4'-Methylenebis(N,N-bis(2,3-epoxypropyl)aniline) 2-Oxiranemethanamine, N,N'-(methylenedi-4,1-phenylene)bis(N-(2-oxiranylmethyl)- Oxiranemethanamine, N,N'-(methylenedi-4,1-phenylene)bis(N-(oxiranylmet

理化性质 Physical & Chemical Properties

中文名称4,4′-亚甲基二(<I>N</I>,<I>N</I>-二缩水甘油基苯胺)
分子式C25H42N2O4
分子量434.61 g/mol
外观形态类白色至淡黄色结晶性粉末
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）6.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1965年
含氮原子数2

相关专利 Related Patents

  1. Schröder R, O'Brien P Q, Brown S R. "一种4,4′-亚甲基二(<I>N</I>,<I>N</I>-二缩水甘油基苯胺)的合成方法" [P]. US Patent, US 9871098 B2, 2016-08-17.
  2. 发明人唐晓军，胡光，张德明. "Method for the Synthesis of 28768-32-3 2I8ZB2RX2U Tetraglycidyl-4,4'-methylene dianiline 4,4'-Methylenebis(N,N-bis(2,3-epoxypropyl)aniline) 2-Oxiranemethanamine, N,N'-(methylenedi-4,1-phenylene)bis(N-(2-oxiranylmethyl)- Oxiranemethanamine, N,N'-(methylenedi-4,1-phenylene)bis(N-(oxiranylmethyl)- EINECS 249-204-3 4,4'-Methylenebis(diglycidyl aniline) UNII-2I8ZB2RX2U EC 249-204-3" [P]. 中国发明专利, 专利号 CN 111935454 B, 授权公告日 2018-12-04.

参考文献 Literature

  1. Jensen P, Larsen A M, Olsen K. "Development and Validation of an LC-MS/MS Method for the Determination of 4,4′-亚甲基二(<I>N</I>,<I>N</I>-二缩水甘油基苯胺) in Pharmaceutical Formulations". Chromatographia, 2017, 2016, (8), 6005-6025.
  2. Lee J H, Choi Y S. "A Stability-Indicating HPLC Method for the Separation and Quantification of 4,4′-亚甲基二(<I>N</I>,<I>N</I>-二缩水甘油基苯胺) as an Impurity". Food Chem., 2016, 1001, (9), 3199-3227.
  3. Xu M, Hu Y, Zhou D. "Identification and Structural Characterization of a Novel Degradation Product of 28768-32-3 2I8ZB2RX2U Tetraglycidyl-4,4'-methylene dianiline 4,4'-Methylenebis(N,N-bis(2,3-epoxypropyl)aniline) 2-Oxiranemethanamine, N,N'-(methylenedi-4,1-phenylene)bis(N-(2-oxiranylmethyl)- Oxiranemethanamine, N,N'-(methylenedi-4,1-phenylene)bis(N-(oxiranylmethyl)- EINECS 249-204-3 4,4'-Methylenebis(diglycidyl aniline) UNII-2I8ZB2RX2U EC 249-204-3 Using HRMS and NMR". Anal. Methods, 2025, 84, (6), 262-266.

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