CAS 2889-31-8
(+/-)-2-Hydroxyglutaric acid 2,3-Dideoxypentaric acid 2-Hydroxyglutarate 2-Hydroxyglutaric acid 2-Hydroxypentanedioic acid 2889-31-8 DL-2-Hydroxyglutaric Glutaric acid, 2-hydroxy- Glutaric acid, 2-hydroxy- (6CI,7CI,8CI) Pentanedioic acid, 2-hydroxy- Pentanedioic acid, 2-hydroxy- (9CI) alpha-Hydroxyglutarate alpha-Hydroxyglutaric acid
| CAS 号 | 2889-31-8 |
| 分子式 | C5H8O5 |
| 分子量 | 148.11 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
（(+/-)-2-Hydroxyglutaric acid 2,3-Dideoxypentaric acid 2-Hydroxyglutarate 2-Hydroxyglutaric acid 2-Hydroxypentanedioic acid 2889-31-8 DL-2-Hydroxyglutaric Glutaric acid, 2-hydroxy- Glutaric acid, 2-hydroxy- (6CI,7CI,8CI) Pentanedioic acid, 2-hydroxy- Pentanedioic acid, 2-hydroxy- (9CI) alpha-Hydroxyglutarate alpha-Hydroxyglutaric acid）是药物分析与质量控制领域常用的药物标准品，CAS 号 2889-31-8。分子式 C5H8O5，分子量 148.11。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。
在定量分析中，可作为校准标准或内标物使用，适用于多种检测技术平台（UV-Vis, FLD, MS, FID）。 化学式为 C5H8O5 的（(+/-)-2-Hydroxyglutaric acid 2,3-Dideoxypentaric acid 2-Hydroxyglutarate 2-Hydroxyglutaric acid 2-Hydroxypentanedioic acid 2889-31-8 DL-2-Hydroxyglutaric Glutaric acid, 2-hydroxy- Glutaric acid, 2-hydroxy- (6CI,7CI,8CI) Pentanedioic acid, 2-hydroxy- Pentanedioic acid, 2-hydroxy- (9CI) alpha-Hydroxyglutarate alpha-Hydroxyglutaric acid），其CAS登记号是 2889-31-8，分子量为 148.11 g/mol。 （C5H8O5）含有糖类衍生物。具有较强的吸湿性，羧基赋予其一定的酸性特征，这些物理化学性
应用场景：（(+/-)-2-Hydroxyglutaric acid 2,3-Dideoxypentaric acid 2-Hydroxyglutarate 2-Hydroxyglutaric acid 2-Hydroxypentanedioic acid 2889-31-8 DL-2-Hydroxyglutaric Glutaric acid, 2-hydroxy- Glutaric acid, 2-hydroxy- (6CI,7CI,8CI) Pentanedioic acid, 2-hydroxy- Pentanedioic acid, 2-hydroxy- (9CI) alpha-Hydroxy
理化性质 Physical & Chemical Properties
| 中文名称 | |
| 分子式 | C5H8O5 |
| 分子量 | 148.11 g/mol |
| 外观形态 | 白色至类白色液体 |
| 纯度 | 97%+ |
| 储存条件 | 2-8°C冷藏保存，密封防潮 |
| 溶解性参考 | 可溶于甲醇、乙醇、DMSO、水 |
| 稳定性 | 具有吸湿性，开封后应立即密封 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 2.0 |
| CAS登记年份（估） | 1957年 |
相关专利 Related Patents
- Johansson L, Schröder R, Rossi M. "一种的合成方法" [P]. European Patent, EP 3813386 A1, 2019-03-02.
- Klinger H, Lee S K, Stevens L M. "Method for the Synthesis of (+/-)-2-Hydroxyglutaric acid 2,3-Dideoxypentaric acid 2-Hydroxyglutarate 2-Hydroxyglutaric acid 2-Hydroxypentanedioic acid 2889-31-8 DL-2-Hydroxyglutaric Glutaric acid, 2-hydroxy- Glutaric acid, 2-hydroxy- (6CI,7CI,8CI) Pentanedioic acid, 2-hydroxy- Pentanedioic acid, 2-hydroxy- (9CI) alpha-Hydroxyglutarate alpha-Hydroxyglutaric acid" [P]. US Patent, US 11037275 B2, 2017-05-24.
- 发明人冯建国，孙丽萍，李文辉. "A Process for Preparing High-Purity (+/-)-2-Hydroxyglutaric acid 2,3-Dideoxypentaric acid 2-Hydroxyglutarate 2-Hydroxyglutaric acid 2-Hydroxypentanedioic acid 2889-31-8 DL-2-Hydroxyglutaric Glutaric acid, 2-hydroxy- Glutaric acid, 2-hydroxy- (6CI,7CI,8CI) Pentanedioic acid, 2-hydroxy- Pentanedioic acid, 2-hydroxy- (9CI) alpha-Hydroxyglutarate alpha-Hydroxyglutaric acid" [P]. 中国发明专利, 专利号 CN 116098272 B, 授权公告日 2020-05-05.
参考文献 Literature
- Smith J A, Johnson M B. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". Rapid Commun. Mass Spectrom., 2014, 1249, (7), 769-785.
- Zhou X P, Huang L, Wu G. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". J. Pharm. Biomed. Anal., 2015, 113, 7409-7432.
- Chen X Y, Liu M, Zhao W Q. "Identification and Structural Characterization of a Novel Degradation Product of (+/-)-2-Hydroxyglutaric acid 2,3-Dideoxypentaric acid 2-Hydroxyglutarate 2-Hydroxyglutaric acid 2-Hydroxypentanedioic acid 2889-31-8 DL-2-Hydroxyglutaric Glutaric acid, 2-hydroxy- Glutaric acid, 2-hydroxy- (6CI,7CI,8CI) Pentanedioic acid, 2-hydroxy- Pentanedioic acid, 2-hydroxy- (9CI) alpha-Hydroxyglutarate alpha-Hydroxyglutaric acid Using HRMS and NMR". Anal. Chem., 2020, 2000, (1), 4657-4672.
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