三氟乙酸银 CAS 2966-50-9

Trifluoroacetic acid, silver salt Silver mono(trifluoroacetate) Silver perfluoroacetate Silver trifluoroacetate Silver(1+) 2,2,2-trifluoroacetate Silver(1+) trifluoroacetate Silver(I) trifluoroacetate Siver(I) trifluoroacetate Trifluoroacetic acid silver(1+) salt 2966-50-9

纯度 97%+现货药物标准品
CAS 号2966-50-9
分子式C2AgF3O2
分子量220.88 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

三氟乙酸银 Trifluoroacetic acid, silver salt Silver mono(trifluoroacetate) Silver perfluoroacetate Silver trifluoroacetate Silver(1+) 2,2,2-trifluoroacetate Silver(1+) trifluoroacetate Silver(I) trifluoroacetate Siver(I) trifluoroacetate Trifluoroacetic acid silver(1+) salt 2966-50-9 CAS 2966-50-9 结构式 Chemical Structure

产品介绍 Description

三氟乙酸银（Trifluoroacetic acid, silver salt Silver mono(trifluoroacetate) Silver perfluoroacetate Silver trifluoroacetate Silver(1+) 2,2,2-trifluoroacetate Silver(1+) trifluoroacetate Silver(I) trifluoroacetate Siver(I) trifluoroacetate Trifluoroacetic acid silver(1+) salt 2966-50-9，CAS 号 2966-50-9）是 CATO 佳途自主生产的药物标准品，分子式 C2AgF3O2，分子量 220.88。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

三氟乙酸银的产生途径与其化学式中羧酸类，含羟基，含醚键，含氟取代密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 化学式为 C2AgF3O2 的三氟乙酸银（Trifluoroacetic acid, silver salt Silver mono(trifluoroacetate) Silver perfluoroacetate Silver trifluoroacetate Silver(1+) 2,2,2-trifluoroacetate Silver(1+) trifluoroacetate Silver(I) trifluoroacetate Siver(I) trifluoroacetate Trifluoroacetic acid silver(1+) salt 2966-50-9），其CAS登记号是 2966-50-9，分子量为 220.88 g/mol。 依据分子式为 C2AgF3O2 的三氟乙酸银结构特征，其分子内含羧酸类，含羟基，含醚键，含氟取代，这意味着该化合物在红外光谱中会呈现特征性的官能团伸缩振动信号。分子量 220.88 g/mol

应用场景：三氟乙酸银（Trifluoroacetic acid, silver salt Silver mono(trifluoroacetate) Silver perfluoroacetate Silver trifluoroacetate Silver(1+) 2,2,2-trifluoroacetate Silver(1+) trifluoroacetate Silver(I) trifluoroacetate Siver(I) trifluoroacetate Trifluoroacetic acid silver(1+) salt 2966-50-9）作为药物标准品，在化学分析分析领域承担着

理化性质 Physical & Chemical Properties

中文名称三氟乙酸银
分子式C2AgF3O2
分子量220.88 g/mol
外观形态白色至类白色结晶性粉末。（具有轻微卤代物特征气味，挥发性较低）
纯度97%+
储存条件室温保存，密闭保存防止挥发
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性在推荐条件下性质稳定
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）1.5
CAS登记年份（估）1957年
卤素含量F取代

相关专利 Related Patents

  1. 发明人孙丽萍，徐明华，钱学锋. "一种三氟乙酸银的合成方法" [P]. 中国发明专利, 专利号 CN 108384415 B, 授权公告日 2022-09-20.
  2. 发明人郭海燕，胡光，王建平. "Method for the Synthesis of Trifluoroacetic acid, silver salt Silver mono(trifluoroacetate) Silver perfluoroacetate Silver trifluoroacetate Silver(1+) 2,2,2-trifluoroacetate Silver(1+) trifluoroacetate Silver(I) trifluoroacetate Siver(I) trifluoroacetate Trifluoroacetic acid silver(1+) salt 2966-50-9" [P]. 中国发明专利, 专利号 CN 116844574 A, 授权公告日 2015-05-14.

参考文献 Literature

  1. O'Brien K, Kennedy M L. "Development and Validation of an LC-MS/MS Method for the Determination of 三氟乙酸银 in Pharmaceutical Formulations". Molecules, 2014, 805, 3488-3492.
  2. Kim S H, Park J Y. "A Stability-Indicating HPLC Method for the Separation and Quantification of 三氟乙酸银 as an Impurity". J. Nat. Prod., 2025, 1287, (6), 4298-4309.
  3. Wang L, Li J, Zhang H. "Identification and Structural Characterization of a Novel Degradation Product of Trifluoroacetic acid, silver salt Silver mono(trifluoroacetate) Silver perfluoroacetate Silver trifluoroacetate Silver(1+) 2,2,2-trifluoroacetate Silver(1+) trifluoroacetate Silver(I) trifluoroacetate Siver(I) trifluoroacetate Trifluoroacetic acid silver(1+) salt 2966-50-9 Using HRMS and NMR". Anal. Chim. Acta, 2018, 517, (1), 3215-3237.
  4. Lee J H, Choi Y S. "Forced Degradation Studies to Evaluate 三氟乙酸银 Profile in Drug Substances According to ICH Guidelines". Chemosphere, 2019, 2234, (5), 2439-2467.

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