3,5-Difluoropyridine-2-carbonitrile CAS 298709-29-2

2-CYANO-3,5-DIFLUOROPYRIDINE 2-CYANO-3,5-DIFLUORPYRIDINE 2-PYRIDINECARBONITRILE, 3,5-DIFLUORO- 298709-29-2 3,5-DIFLUORO-2-CYANOPYRIDINE 3,5-DIFLUORO-2-PYRIDINECARBONITRILE 3,5-DIFLUOROPICOLINITRILE 3,5-DIFLUOROPICOLINONITRILE 3,5-DIFLUOROPYRIDINE-2-CARBONITRILE ABBYPHARMA AP-15-5175 LF10441

纯度 97%+现货药物标准品
CAS 号298709-29-2
分子式C6H8F2N2
分子量146.14 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

3,5-Difluoropyridine-2-carbonitrile 2-CYANO-3,5-DIFLUOROPYRIDINE 2-CYANO-3,5-DIFLUORPYRIDINE 2-PYRIDINECARBONITRILE, 3,5-DIFLUORO- 298709-29-2 3,5-DIFLUORO-2-CYANOPYRIDINE 3,5-DIFLUORO-2-PYRIDINECARBONITRILE 3,5-DIFLUOROPICOLINITRILE 3,5-DIFLUOROPICOLINONITRILE 3,5-DIFLUOROPYRIDINE-2-CARBONITRILE ABBYPHARMA AP-15-5175 LF10441 CAS 298709-29-2 结构式 Chemical Structure

产品介绍 Description

3,5-Difluoropyridine-2-carbonitrile（英文名 2-CYANO-3,5-DIFLUOROPYRIDINE 2-CYANO-3,5-DIFLUORPYRIDINE 2-PYRIDINECARBONITRILE, 3,5-DIFLUORO- 298709-29-2 3,5-DIFLUORO-2-CYANOPYRIDINE 3,5-DIFLUORO-2-PYRIDINECARBONITRILE 3,5-DIFLUOROPICOLINITRILE 3,5-DIFLUOROPICOLINONITRILE 3,5-DIFLUOROPYRIDINE-2-CARBONITRILE ABBYPHARMA AP-15-5175 LF10441，CAS 298709-29-2）属于药物标准品。分子式 C6H8F2N2，分子量 146.14。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

与同类药物标准品相比，3,5-Difluoropyridine-2-carbonitrile的分子量为146.14 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 化学式为 C6H8F2N2 的3,5-Difluoropyridine-2-carbonitrile（2-CYANO-3,5-DIFLUOROPYRIDINE 2-CYANO-3,5-DIFLUORPYRIDINE 2-PYRIDINECARBONITRILE, 3,5-DIFLUORO- 298709-29-2 3,5-DIFLUORO-2-CYANOPYRIDINE 3,5-DIFLUORO-2-PYRIDINECARBONITRILE 3,5-DIFLUOROPICOLINITRILE 3,5-DIFLUOROPICOLINONITRILE 3,5-DIFLUOROPYRIDINE-2-CARBONITRILE ABBYPHARMA AP-15-5175 LF10441），其CAS登记号是 298709-29-2，分子量为 146.14 g/mol。 依据分子式为 C6H8F2N2 的3,5-

应用场景：3,5-Difluoropyridine-2-carbonitrile（2-CYANO-3,5-DIFLUOROPYRIDINE 2-CYANO-3,5-DIFLUORPYRIDINE 2-PYRIDINECARBONITRILE, 3,5-DIFLUORO- 298709-29-2 3,5-DIFLUORO-2-CYANOPYRIDINE 3,5-DIFLUORO-2-PYRIDINECARBONITRILE 3,5-DIFLUOROPICOLINITRILE 3,5-DIFLUOROPICOLINONITRILE 3,5-DIFLUOROPYRIDINE-2-CARBONITRILE AB

理化性质 Physical & Chemical Properties

中文名称3,5-Difluoropyridine-2-carbonitrile
分子式C6H8F2N2
分子量146.14 g/mol
外观形态白色至淡黄色液体。（具有轻微卤代物特征气味，具有氨/胺类微弱气味，挥发性较低）
纯度97%+
储存条件2-8°C冷藏保存，避光，密闭保存防止挥发
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.0
UV特征有紫外吸收
CAS登记年份（估）2025年
卤素含量F取代
含氮原子数2

相关专利 Related Patents

  1. 发明人冯建国，王建平，高志强. "一种3,5-Difluoropyridine-2-carbonitrile的合成方法" [P]. 中国发明专利, 专利号 CN 116015295 A, 授权公告日 2015-07-17.
  2. Kumar R, Brown S R, Park J H. "Method for the Synthesis of 2-CYANO-3,5-DIFLUOROPYRIDINE 2-CYANO-3,5-DIFLUORPYRIDINE 2-PYRIDINECARBONITRILE, 3,5-DIFLUORO- 298709-29-2 3,5-DIFLUORO-2-CYANOPYRIDINE 3,5-DIFLUORO-2-PYRIDINECARBONITRILE 3,5-DIFLUOROPICOLINITRILE 3,5-DIFLUOROPICOLINONITRILE 3,5-DIFLUOROPYRIDINE-2-CARBONITRILE ABBYPHARMA AP-15-5175 LF10441" [P]. US Patent, US 9046658 B2, 2016-02-12.

参考文献 Literature

  1. Chen X Y, Liu M, Zhao W Q. "Development and Validation of an LC-MS/MS Method for the Determination of 3,5-Difluoropyridine-2-carbonitrile in Pharmaceutical Formulations". Molecules, 2020, 288, 7730-7755.
  2. Kim S H, Park J Y. "A Stability-Indicating HPLC Method for the Separation and Quantification of 3,5-Difluoropyridine-2-carbonitrile as an Impurity". J. Chromatogr. A, 2010, 2457, (3), 1283-1295.
  3. Kowalski T, Nowak Z. "Identification and Structural Characterization of a Novel Degradation Product of 2-CYANO-3,5-DIFLUOROPYRIDINE 2-CYANO-3,5-DIFLUORPYRIDINE 2-PYRIDINECARBONITRILE, 3,5-DIFLUORO- 298709-29-2 3,5-DIFLUORO-2-CYANOPYRIDINE 3,5-DIFLUORO-2-PYRIDINECARBONITRILE 3,5-DIFLUOROPICOLINITRILE 3,5-DIFLUOROPICOLINONITRILE 3,5-DIFLUOROPYRIDINE-2-CARBONITRILE ABBYPHARMA AP-15-5175 LF10441 Using HRMS and NMR". Anal. Chem., 2023, 337, (10), 7350-7378.

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