双酚乙氧基化物 CAS 32492-61-8

32492-61-8 Poly(oxy-1,2-ethanediyl), alpha,alpha'-((1-methylethylidene)di-4,1-phenylene)bis(omega-hydroxy- 4,4'-Isopropylidenediphenol, ethoxylated 2,2-Bis(4-hydroxyphenyl)propane ethylene oxide adduct Argopol KA BA 10 BA 3 BA 4 BAP 2 Bisol 2E Bisol 4EN Bisphenol A bis(polyethylene glycol) ether Bisphenol A polyethylene glycol ether (1:2) Bisphenol A - ethylene oxide adduct BPE 20F D 24 (polyoxyalkylene) DA 350 DA 350F Dianol 220 Dianol 2211 Dianol 265 DK Flex BPE 2P Ethoxylated Biphenol A G 1672 Macol 206E Macol 206EM Macol 98 Macol RD 202E Newcol 1900 Newcol BA 10 Newcol BA 4 Syn Fac 8008 Newcol BA 2 Newpol BPE 100 Newpol BPE 180 Newpol BPE 20NK Newpol BPE 40 Nissan Uniol Ba 10 Nissan Uniol BA 8 Nissan Uniol DA 1000 Nissan Uniol DA 350 Nissan Uniol DA 350F Nissan Uniol DA 400 Nissan Uniol DA 400F Nissan Uniol DA 700 Nissan Uniol DB 360 Photonol 7025 PM 8701L Polyethylene glycol ether with 4,4'-isopropylidenediphenol Polyethylene glycol ether with bisphenol A (2:1) Polyoxyethylene(2,2)-2-2-bis(4-hydroxyphenyl)propane Polyethylene glycol, diether with bisphenol A (2:1) EC 500-082-2 Polyethylene glycol, ether with Bisphenol A (2:1)

纯度 97%+现货药物标准品
CAS 号32492-61-8
分子式C15H28O2 C2H6O2
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

双酚乙氧基化物 32492-61-8 Poly(oxy-1,2-ethanediyl), alpha,alpha'-((1-methylethylidene)di-4,1-phenylene)bis(omega-hydroxy- 4,4'-Isopropylidenediphenol, ethoxylated 2,2-Bis(4-hydroxyphenyl)propane ethylene oxide adduct Argopol KA BA 10 BA 3 BA 4 BAP 2 Bisol 2E Bisol 4EN Bisphenol A bis(polyethylene glycol) ether Bisphenol A polyethylene glycol ether (1:2) Bisphenol A - ethylene oxide adduct BPE 20F D 24 (polyoxyalkylene) DA 350 DA 350F Dianol 220 Dianol 2211 Dianol 265 DK Flex BPE 2P Ethoxylated Biphenol A G 1672 Macol 206E Macol 206EM Macol 98 Macol RD 202E Newcol 1900 Newcol BA 10 Newcol BA 4 Syn Fac 8008 Newcol BA 2 Newpol BPE 100 Newpol BPE 180 Newpol BPE 20NK Newpol BPE 40 Nissan Uniol Ba 10 Nissan Uniol BA 8 Nissan Uniol DA 1000 Nissan Uniol DA 350 Nissan Uniol DA 350F Nissan Uniol DA 400 Nissan Uniol DA 400F Nissan Uniol DA 700 Nissan Uniol DB 360 Photonol 7025 PM 8701L Polyethylene glycol ether with 4,4'-isopropylidenediphenol Polyethylene glycol ether with bisphenol A (2:1) Polyoxyethylene(2,2)-2-2-bis(4-hydroxyphenyl)propane Polyethylene glycol, diether with bisphenol A (2:1) EC 500-082-2 Polyethylene glycol, ether with Bisphenol A (2:1) CAS 32492-61-8 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的双酚乙氧基化物（32492-61-8 Poly(oxy-1,2-ethanediyl), alpha,alpha'-((1-methylethylidene)di-4,1-phenylene)bis(omega-hydroxy- 4,4'-Isopropylidenediphenol, ethoxylated 2,2-Bis(4-hydroxyphenyl)propane ethylene oxide adduct Argopol KA BA 10 BA 3 BA 4 BAP 2 Bisol 2E Bisol 4EN Bisphenol A bis(polyethylene glycol) ether Bisphenol A polyethylene glycol ether (1:2) Bisphenol A - ethylene oxide adduct BPE 20F D 24 (polyoxyalkylene) DA 350 DA 350F Dianol 220 Dianol 2211 Dianol 265 DK Flex BPE 2P Ethoxylated Biphenol A G 1672 Macol 206E Macol 206EM Macol 98 Macol RD 202E Newcol 1900 Newcol BA 10 Newcol BA 4 Syn Fac 8008 Newcol BA 2 Newpol BPE 100 Newpol BPE 180 Newpol BPE 20NK Newpol BPE 40 Nissan Uniol Ba 10 Nissan Uniol BA 8 Nissan Uniol DA 1000 Nissan Uniol DA 350 Nissan Uniol DA 350F Nissan Uniol DA 400 Nissan Uniol DA 400F Nissan Uniol DA 700 Nissan Uniol DB 360 Photonol 7025 PM 8701L Polyethylene glycol ether with 4,4'-isopropylidenediphenol Polyethylene glycol ether with bisphenol A (2:1) Polyoxyethylene(2,2)-2-2-bis(4-hydroxyphenyl)propane Polyethylene glycol, diether with bisphenol A (2:1) EC 500-082-2 Polyethylene glycol, ether with Bisphenol A (2:1)）为药物标准品，CAS 登记号 32492-61-8，分子式 C15H28O2 C2H6O2。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

在质量保证方面，双酚乙氧基化物的生产和定值严格遵循ISO 17034:2016（认证标准物质生产者）的要求。纯度定值采用质量平衡法和定量核磁共振（qNMR）等多种正交方法进行交叉验证，扩展不确定度报告为95%置信水平（k=2）。每个批次的均匀性和稳定性均经过独立的统计评估。 化学式为 C15H28O2 C2H6O2 的双酚乙氧基化物（32492-61-8 Poly(oxy-1,2-ethanediyl), alpha,alpha'-((1-methylethylidene)di-4,1-phenylene)bis(omega-hydroxy- 4,4'-Isopropylidenediphenol, ethoxylated 2,2-Bis(4-hydroxyphenyl)propane ethylene oxide adduct Argopol KA BA 10 BA 3 BA 4 BAP 2 Bisol 2E Bisol 4EN Bisphenol A bis(polyethylene glycol) ether Bisphenol A polyethyle

应用场景：从实际应用出发，双酚乙氧基化物（CAS 32492-61-8）在化学分析中作为关键的基准对照物质。 推荐以双酚乙氧基化物配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用乙腈为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用乙腈配制，于室温保存，密封防潮条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用，防止吸潮影响称量准确性。

理化性质 Physical & Chemical Properties

中文名称双酚乙氧基化物
分子式C15H28O2 C2H6O2
分子量302.45 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件室温保存，密封防潮
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO
稳定性在推荐条件下性质稳定
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）1.0
CAS登记年份（估）1966年

相关专利 Related Patents

  1. 发明人林芳，孙丽萍，郭海燕. "一种双酚乙氧基化物的合成方法" [P]. 中国发明专利, 专利号 CN 111181013 A, 授权公告日 2017-07-11.
  2. 发明人沈红梅，张德明，罗永刚. "Method for the Synthesis of 32492-61-8 Poly(oxy-1,2-ethanediyl), alpha,alpha'-((1-methylethylidene)di-4,1-phenylene)bis(omega-hydroxy- 4,4'-Isopropylidenediphenol, ethoxylated 2,2-Bis(4-hydroxyphenyl)propane ethylene oxide adduct Argopol KA BA 10 BA 3 BA 4 BAP 2 Bisol 2E Bisol 4EN Bisphenol A bis(polyethylene glycol) ether Bisphenol A polyethylene glycol ether (1:2) Bisphenol A - ethylene oxide adduct BPE 20F D 24 (polyoxyalkylene) DA 350 DA 350F Dianol 220 Dianol 2211 Dianol 265 DK Flex BPE 2P Ethoxylated Biphenol A G 1672 Macol 206E Macol 206EM Macol 98 Macol RD 202E Newcol 1900 Newcol BA 10 Newcol BA 4 Syn Fac 8008 Newcol BA 2 Newpol BPE 100 Newpol BPE 180 Newpol BPE 20NK Newpol BPE 40 Nissan Uniol Ba 10 Nissan Uniol BA 8 Nissan Uniol DA 1000 Nissan Uniol DA 350 Nissan Uniol DA 350F Nissan Uniol DA 400 Nissan Uniol DA 400F Nissan Uniol DA 700 Nissan Uniol DB 360 Photonol 7025 PM 8701L Polyethylene glycol ether with 4,4'-isopropylidenediphenol Polyethylene glycol ether with bisphenol A (2:1) Polyoxyethylene(2,2)-2-2-bis(4-hydroxyphenyl)propane Polyethylene glycol, diether with bisphenol A (2:1) EC 500-082-2 Polyethylene glycol, ether with Bisphenol A (2:1)" [P]. 中国发明专利, 专利号 CN 116504407 B, 授权公告日 2016-04-15.
  3. 发明人唐晓军，周伟，高志强. "A Process for Preparing High-Purity 32492-61-8 Poly(oxy-1,2-ethanediyl), alpha,alpha'-((1-methylethylidene)di-4,1-phenylene)bis(omega-hydroxy- 4,4'-Isopropylidenediphenol, ethoxylated 2,2-Bis(4-hydroxyphenyl)propane ethylene oxide adduct Argopol KA BA 10 BA 3 BA 4 BAP 2 Bisol 2E Bisol 4EN Bisphenol A bis(polyethylene glycol) ether Bisphenol A polyethylene glycol ether (1:2) Bisphenol A - ethylene oxide adduct BPE 20F D 24 (polyoxyalkylene) DA 350 DA 350F Dianol 220 Dianol 2211 Dianol 265 DK Flex BPE 2P Ethoxylated Biphenol A G 1672 Macol 206E Macol 206EM Macol 98 Macol RD 202E Newcol 1900 Newcol BA 10 Newcol BA 4 Syn Fac 8008 Newcol BA 2 Newpol BPE 100 Newpol BPE 180 Newpol BPE 20NK Newpol BPE 40 Nissan Uniol Ba 10 Nissan Uniol BA 8 Nissan Uniol DA 1000 Nissan Uniol DA 350 Nissan Uniol DA 350F Nissan Uniol DA 400 Nissan Uniol DA 400F Nissan Uniol DA 700 Nissan Uniol DB 360 Photonol 7025 PM 8701L Polyethylene glycol ether with 4,4'-isopropylidenediphenol Polyethylene glycol ether with bisphenol A (2:1) Polyoxyethylene(2,2)-2-2-bis(4-hydroxyphenyl)propane Polyethylene glycol, diether with bisphenol A (2:1) EC 500-082-2 Polyethylene glycol, ether with Bisphenol A (2:1)" [P]. 中国发明专利, 专利号 CN 109225491 A, 授权公告日 2025-01-14.

参考文献 Literature

  1. Yamamoto K, Tanaka H, Suzuki T. "Development and Validation of an LC-MS/MS Method for the Determination of 双酚乙氧基化物 in Pharmaceutical Formulations". Anal. Chim. Acta, 2012, 428, (8), 4445-4463.
  2. Jensen P, Larsen A M, Olsen K. "A Stability-Indicating HPLC Method for the Separation and Quantification of 双酚乙氧基化物 as an Impurity". Environ. Sci. Technol., 2017, 680, (7), 2993-3023.
  3. Zhou X P, Huang L, Wu G. "Identification and Structural Characterization of a Novel Degradation Product of 32492-61-8 Poly(oxy-1,2-ethanediyl), alpha,alpha'-((1-methylethylidene)di-4,1-phenylene)bis(omega-hydroxy- 4,4'-Isopropylidenediphenol, ethoxylated 2,2-Bis(4-hydroxyphenyl)propane ethylene oxide adduct Argopol KA BA 10 BA 3 BA 4 BAP 2 Bisol 2E Bisol 4EN Bisphenol A bis(polyethylene glycol) ether Bisphenol A polyethylene glycol ether (1:2) Bisphenol A - ethylene oxide adduct BPE 20F D 24 (polyoxyalkylene) DA 350 DA 350F Dianol 220 Dianol 2211 Dianol 265 DK Flex BPE 2P Ethoxylated Biphenol A G 1672 Macol 206E Macol 206EM Macol 98 Macol RD 202E Newcol 1900 Newcol BA 10 Newcol BA 4 Syn Fac 8008 Newcol BA 2 Newpol BPE 100 Newpol BPE 180 Newpol BPE 20NK Newpol BPE 40 Nissan Uniol Ba 10 Nissan Uniol BA 8 Nissan Uniol DA 1000 Nissan Uniol DA 350 Nissan Uniol DA 350F Nissan Uniol DA 400 Nissan Uniol DA 400F Nissan Uniol DA 700 Nissan Uniol DB 360 Photonol 7025 PM 8701L Polyethylene glycol ether with 4,4'-isopropylidenediphenol Polyethylene glycol ether with bisphenol A (2:1) Polyoxyethylene(2,2)-2-2-bis(4-hydroxyphenyl)propane Polyethylene glycol, diether with bisphenol A (2:1) EC 500-082-2 Polyethylene glycol, ether with Bisphenol A (2:1) Using HRMS and NMR". Chromatographia, 2022, 2429, 9368-9386.
  4. Kumar A, Sharma P, Patel R S. "Forced Degradation Studies to Evaluate 双酚乙氧基化物 Profile in Drug Substances According to ICH Guidelines". J. Pharm. Biomed. Anal., 2021, 1612, 6153-6168.

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