(<I>R</I>)-Ru(OAc)<SUB>2</SUB>(BINAP) CAS 325146-81-4

Diacetato[(R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium(II), Ru(OAc)2[(R)-binap] 325146-81-4 (R)-RU(OAC)2(BINAP);(S)-RU(OAC)2(BINAP);DIACETATO[(R)-(+)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL]RUTHENIUM(II);DIACETATO[(R)-(-)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL]RUTHENIUM(II);DIACETATO[(S)-(-)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL]RUTHENIUM(II);RU(OAC)2[(R)-BINAP];RU(OAC)2[(S)-BINAP];RU-BINAP;Diacetato[(R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium(II), ?Ru(OAc)2[(R)-binap] SC10141

纯度 97%+现货药物标准品
CAS 号325146-81-4
分子式C44H76P2 C4H6O4Ru
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(<I>R</I>)-Ru(OAc)<SUB>2</SUB>(BINAP) Diacetato[(R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium(II), Ru(OAc)2[(R)-binap] 325146-81-4 (R)-RU(OAC)2(BINAP);(S)-RU(OAC)2(BINAP);DIACETATO[(R)-(+)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL]RUTHENIUM(II);DIACETATO[(R)-(-)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL]RUTHENIUM(II);DIACETATO[(S)-(-)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL]RUTHENIUM(II);RU(OAC)2[(R)-BINAP];RU(OAC)2[(S)-BINAP];RU-BINAP;Diacetato[(R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium(II), ?Ru(OAc)2[(R)-binap] SC10141 CAS 325146-81-4 结构式 Chemical Structure

产品介绍 Description

(<I>R</I>)-Ru(OAc)<SUB>2</SUB>(BINAP)（Diacetato[(R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium(II), Ru(OAc)2[(R)-binap] 325146-81-4 (R)-RU(OAC)2(BINAP);(S)-RU(OAC)2(BINAP);DIACETATO[(R)-(+)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL]RUTHENIUM(II);DIACETATO[(R)-(-)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL]RUTHENIUM(II);DIACETATO[(S)-(-)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL]RUTHENIUM(II);RU(OAC)2[(R)-BINAP];RU(OAC)2[(S)-BINAP];RU-BINAP;Diacetato[(R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium(II), ?Ru(OAc)2[(R)-binap] SC10141，CAS 号 325146-81-4）是 CATO 佳途自主生产的药物标准品，分子式 C44H76P2 C4H6O4Ru。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

(<I>R</I>)-Ru(OAc)<SUB>2</SUB>(BINAP)（C44H76P2 C4H6O4Ru）含有含磷酸酯基，羧酸类，含羟基，含醚键，多环芳烃。较高的碳氢比使其脂溶性较好，羧基赋予其一定的酸性特征，这些物理化学性质直接决定了其标准溶液的最佳配制方案和储存策略。由于结构中存在共轭发色团，该化合物在200-400 nm区间具有显著的紫外吸收，便于HPLC-UV检测。 CAS编号 325146-81-4 对应的化合物(<I>R</I>)-Ru(OAc)<SUB>2</SUB>(BINAP)（英文标识 Diacetato(R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthylruthenium(II), Ru(OAc)2(R)-binap 325146-81-4 (R)-RU(OAC)2(BINAP);(S)-RU(OAC)2(BINAP);DIACETATO(R)-(+)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYLRUTHENIUM(II);DIACETATO(R)-(

应用场景：针对化学分析用途，(<I>R</I>)-Ru(OAc)<SUB>2</SUB>(BINAP)（Diacetato (R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl ruthenium(II), Ru(OAc)2 (R)-binap 325146-81-4 (R)-RU(OAC)2(BINAP);(S)-RU(OAC)2(BINAP);DIACETATO (R)-(+)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL RUTHENIUM(II);DIACETATO (R)-(-)-2,2'-BIS(D

理化性质 Physical & Chemical Properties

中文名称(<I>R</I>)-Ru(OAc)<SUB>2</SUB>(BINAP)
分子式C44H76P2 C4H6O4Ru
分子量886.20 g/mol
外观形态淡黄色至黄色无定形粉末
纯度97%+
储存条件室温保存，避光，密封防潮
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）8.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）2025年

相关专利 Related Patents

  1. 发明人钱学锋，郭海燕，周伟. "一种(<I>R</I>)-Ru(OAc)<SUB>2</SUB>(BINAP)的合成方法" [P]. 中国发明专利, 专利号 CN 111254879 B, 授权公告日 2022-10-27.
  2. 发明人马晓峰，王建平，韩伟. "Method for the Synthesis of Diacetato[(R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium(II), Ru(OAc)2[(R)-binap] 325146-81-4 (R)-RU(OAC)2(BINAP);(S)-RU(OAC)2(BINAP);DIACETATO[(R)-(+)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL]RUTHENIUM(II);DIACETATO[(R)-(-)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL]RUTHENIUM(II);DIACETATO[(S)-(-)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL]RUTHENIUM(II);RU(OAC)2[(R)-BINAP];RU(OAC)2[(S)-BINAP];RU-BINAP;Diacetato[(R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium(II), ?Ru(OAc)2[(R)-binap] SC10141" [P]. 中国发明专利, 专利号 CN 112753316 A, 授权公告日 2023-09-08.
  3. O'Brien P Q, Kumar R, Stevens L M. "A Process for Preparing High-Purity Diacetato[(R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium(II), Ru(OAc)2[(R)-binap] 325146-81-4 (R)-RU(OAC)2(BINAP);(S)-RU(OAC)2(BINAP);DIACETATO[(R)-(+)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL]RUTHENIUM(II);DIACETATO[(R)-(-)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL]RUTHENIUM(II);DIACETATO[(S)-(-)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL]RUTHENIUM(II);RU(OAC)2[(R)-BINAP];RU(OAC)2[(S)-BINAP];RU-BINAP;Diacetato[(R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium(II), ?Ru(OAc)2[(R)-binap] SC10141" [P]. US Patent, US 9872870 B2, 2020-09-06.

参考文献 Literature

  1. Yang F, Sun W, Liu J. "Development and Validation of an LC-MS/MS Method for the Determination of (<I>R</I>)-Ru(OAc)<SUB>2</SUB>(BINAP) in Pharmaceutical Formulations". Talanta, 2025, 1137, 1800-1811.
  2. Martinez C, Lopez D R. "A Stability-Indicating HPLC Method for the Separation and Quantification of (<I>R</I>)-Ru(OAc)<SUB>2</SUB>(BINAP) as an Impurity". Rapid Commun. Mass Spectrom., 2013, 1896, (8), 4717-4733.
  3. Xu M, Hu Y, Zhou D. "Identification and Structural Characterization of a Novel Degradation Product of Diacetato[(R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium(II), Ru(OAc)2[(R)-binap] 325146-81-4 (R)-RU(OAC)2(BINAP);(S)-RU(OAC)2(BINAP);DIACETATO[(R)-(+)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL]RUTHENIUM(II);DIACETATO[(R)-(-)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL]RUTHENIUM(II);DIACETATO[(S)-(-)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL]RUTHENIUM(II);RU(OAC)2[(R)-BINAP];RU(OAC)2[(S)-BINAP];RU-BINAP;Diacetato[(R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium(II), ?Ru(OAc)2[(R)-binap] SC10141 Using HRMS and NMR". Chemosphere, 2016, 1444, 1565-1584.
  4. Martinez C, Lopez D R. "Forced Degradation Studies to Evaluate (<I>R</I>)-Ru(OAc)<SUB>2</SUB>(BINAP) Profile in Drug Substances According to ICH Guidelines". Environ. Sci. Technol., 2023, 680, (9), 5633-5660.

Related Diacetato Standards 同系列产品

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...