三氟甲磺酸锂 CAS 33454-82-9

33454-82-9 1C966KV50I Lithium triflate Lithium trifluoromethanesulphonate Methanesulfonic acid, 1,1,1-trifluoro-, lithium salt (1:1) Methanesulfonic acid, trifluoro-, lithium salt EINECS 251-528-5 Li triflate Lithium trifluoromethanesulfonate NSC 175813 Trifluoromethanesulfonic acid, lithium salt UNII-1C966KV50I

纯度 97%+现货药物标准品
CAS 号33454-82-9
分子式CF3O3S Li
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

三氟甲磺酸锂 33454-82-9 1C966KV50I Lithium triflate Lithium trifluoromethanesulphonate Methanesulfonic acid, 1,1,1-trifluoro-, lithium salt (1:1) Methanesulfonic acid, trifluoro-, lithium salt EINECS 251-528-5 Li triflate Lithium trifluoromethanesulfonate NSC 175813 Trifluoromethanesulfonic acid, lithium salt UNII-1C966KV50I CAS 33454-82-9 结构式 Chemical Structure

产品介绍 Description

三氟甲磺酸锂（33454-82-9 1C966KV50I Lithium triflate Lithium trifluoromethanesulphonate Methanesulfonic acid, 1,1,1-trifluoro-, lithium salt (1:1) Methanesulfonic acid, trifluoro-, lithium salt EINECS 251-528-5 Li triflate Lithium trifluoromethanesulfonate NSC 175813 Trifluoromethanesulfonic acid, lithium salt UNII-1C966KV50I，CAS 号 33454-82-9）是 CATO 佳途自主生产的药物标准品，分子式 CF3O3S Li。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

推荐用于分析方法开发与验证，产品提供完整COA证书，确保ISO 17034标准的量值溯源要求。适用于GLP实验室的日常分析。 CAS编号 33454-82-9 对应的化合物三氟甲磺酸锂（英文标识 33454-82-9 1C966KV50I Lithium triflate Lithium trifluoromethanesulphonate Methanesulfonic acid, 1,1,1-trifluoro-, lithium salt (1:1) Methanesulfonic acid, trifluoro-, lithium salt EINECS 251-528-5 Li triflate Lithium trifluoromethanesulfonate NSC 175813 Trifluoromethanesulfonic acid, lithium salt UNII-1C966KV50I），化学式 CF3O3S Li，相对分子质量 156.00。 三氟甲磺酸锂（分子式 CF3O3S Li）的化学结构中包含含砜基，含氟取代。在反相色谱体系中，其

应用场景：三氟甲磺酸锂（33454-82-9 1C966KV50I Lithium triflate Lithium trifluoromethanesulphonate Methanesulfonic acid, 1,1,1-trifluoro-, lithium salt (1:1) Methanesulfonic acid, trifluoro-, lithium salt EINECS 251-528-5 Li triflate Lithium trifluoromethanesulfonate NSC 175813 Trifluoromethanesulfonic acid, lithium

理化性质 Physical & Chemical Properties

中文名称三氟甲磺酸锂
分子式CF3O3S Li
分子量156.00 g/mol
外观形态白色至类白色结晶性粉末。（具有轻微卤代物特征气味，含硫化合物特征性气味，挥发性较低）
纯度97%+
储存条件2-8°C冷藏保存，密封防潮，密闭保存防止挥发
溶解性参考可溶于甲醇、乙醇、DMSO、水
稳定性具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）0.5
CAS登记年份（估）1966年
卤素含量F取代
含硫原子数1

相关专利 Related Patents

  1. Klinger H, Brown S R, Park J H. "一种三氟甲磺酸锂的合成方法" [P]. US Patent, US 11213646 B2, 2023-01-16.
  2. 发明人张德明，沈红梅，赵玉洁. "Method for the Synthesis of 33454-82-9 1C966KV50I Lithium triflate Lithium trifluoromethanesulphonate Methanesulfonic acid, 1,1,1-trifluoro-, lithium salt (1:1) Methanesulfonic acid, trifluoro-, lithium salt EINECS 251-528-5 Li triflate Lithium trifluoromethanesulfonate NSC 175813 Trifluoromethanesulfonic acid, lithium salt UNII-1C966KV50I" [P]. 中国发明专利, 专利号 CN 109357608 A, 授权公告日 2016-02-11.
  3. 发明人周伟，唐晓军，徐明华. "A Process for Preparing High-Purity 33454-82-9 1C966KV50I Lithium triflate Lithium trifluoromethanesulphonate Methanesulfonic acid, 1,1,1-trifluoro-, lithium salt (1:1) Methanesulfonic acid, trifluoro-, lithium salt EINECS 251-528-5 Li triflate Lithium trifluoromethanesulfonate NSC 175813 Trifluoromethanesulfonic acid, lithium salt UNII-1C966KV50I" [P]. 中国发明专利, 专利号 CN 117432473 B, 授权公告日 2020-07-18.

参考文献 Literature

  1. Hughes D, Roberts J, Thomas A. "Development and Validation of an LC-MS/MS Method for the Determination of 三氟甲磺酸锂 in Pharmaceutical Formulations". Chromatographia, 2019, 463, 3153-3170.
  2. Lee J H, Choi Y S. "A Stability-Indicating HPLC Method for the Separation and Quantification of 三氟甲磺酸锂 as an Impurity". Anal. Chem., 2010, 2048, (12), 7835-7838.
  3. Fischer P, Wagner E. "Identification and Structural Characterization of a Novel Degradation Product of 33454-82-9 1C966KV50I Lithium triflate Lithium trifluoromethanesulphonate Methanesulfonic acid, 1,1,1-trifluoro-, lithium salt (1:1) Methanesulfonic acid, trifluoro-, lithium salt EINECS 251-528-5 Li triflate Lithium trifluoromethanesulfonate NSC 175813 Trifluoromethanesulfonic acid, lithium salt UNII-1C966KV50I Using HRMS and NMR". Food Chem., 2017, 449, (7), 902-929.
  4. Zhou X P, Huang L, Wu G. "Forced Degradation Studies to Evaluate 三氟甲磺酸锂 Profile in Drug Substances According to ICH Guidelines". Anal. Chim. Acta, 2017, 363, (7), 8110-8138.

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