2,2-Dihydroxyazobenzene [Spectrophotometric and fluorimetric reagent for Al, Mg and other metals] CAS 34379-04-9
2,2-Dihydroxyazobenzene [Spectrophotometric and fluorimetric reagent for Al, Mg and other metals]
纯度 97%+现货药物标准品
CAS 号
34379-04-9
分子式
C12H10N2O2
分子量
214.22 g/mol
分类
药物标准品 / 原料药标准品
库存状态
现货
化学结构式 Structure
产品介绍 Description
本产品为药物标准品2,2-Dihydroxyazobenzene [Spectrophotometric and fluorimetric reagent for Al, Mg and other metals](2,2-Dihydroxyazobenzene [Spectrophotometric and fluorimetric reagent for Al, Mg and other metals],CAS 34379-04-9),分子式 C12H10N2O2,分子量 214.22。纯度 97%+。适用于分析方法开发、方法验证及日常质检,CATO 提供全程冷链与全球配送。
2,2-Dihydroxyazobenzene Spectrophotometric and fluorimetric reagent for Al, Mg and other metals的产生途径与其化学式中氨基酸衍生物,酰胺类,含羟基,含醚键密切相关,该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。
CAS编号 34379-04-9 对应的化合物2,2-Dihydroxyazobenzene Spectrophotometric and fluorimetric reagent for Al, Mg and other metals(英文标识 2,2-Dihydroxyazobenzene Spectrophotometric and fluorimetric reagent for Al, Mg and other metals),化学式 C12H10N2O2,相对分子质量 214.22。
从化学结构特征来看,2,2-Dihydroxyazobenzene Spectrophotometric and fluorimetric reagent fo
应用场景:从实际应用出发,2,2-Dihydroxyazobenzene Spectrophotometric and fluorimetric reagent for Al, Mg and other metals (CAS 34379-04-9)在化学分析中作为关键的基准对照物质。 推荐以2,2-Dihydroxyazobenzene Spectrophotometric and fluorimetric reagent for Al, Mg and other metals 配制标准系列工作溶液,用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈(1:1)为溶剂配制储备溶液,根据检测灵敏度
理化性质 Physical & Chemical Properties
中文名称
2,2-Dihydroxyazobenzene [Spectrophotometric and fluorimetric reagent for Al, Mg and other metals]
分子式
C12H10N2O2
分子量
214.22 g/mol
外观形态
淡黄色至黄色结晶性粉末
纯度
97%+
储存条件
2-8°C冷藏保存,避光,密封防潮
溶解性参考
可溶于DMSO、DMF、甲醇
稳定性
空气中长期暴露可能发生缓慢氧化;对光敏感,应避免强光直射;具有吸湿性,开封后应立即密封
化合物类型
药物标准品
子类
原料药标准品
不饱和度(DBE)
9.0
UV特征
有紫外吸收
结构特征
含芳环
CAS登记年份(估)
1966年
含氮原子数
2
相关专利 Related Patents
发明人赵玉洁,王建平,杨光. "一种2,2-Dihydroxyazobenzene [Spectrophotometric and fluorimetric reagent for Al, Mg and other metals]的合成方法" [P]. 中国发明专利, 专利号 CN 116734036 B, 授权公告日 2023-06-26.
发明人朱建伟,李文辉,王建平. "Method for the Synthesis of 2,2-Dihydroxyazobenzene [Spectrophotometric and fluorimetric reagent for Al, Mg and other metals]" [P]. 中国发明专利, 专利号 CN 109579906 A, 授权公告日 2023-08-12.
Roberts E F, Park J H, Mueller T. "A Process for Preparing High-Purity 2,2-Dihydroxyazobenzene [Spectrophotometric and fluorimetric reagent for Al, Mg and other metals]" [P]. US Patent, US 11946966 B2, 2022-06-06.
参考文献 Literature
Garcia M, Rodriguez P. "Development and Validation of an LC-MS/MS Method for the Determination of 2,2-Dihydroxyazobenzene [Spectrophotometric and fluorimetric reagent for Al, Mg and other metals] in Pharmaceutical Formulations". Anal. Chem., 2021, 225, (12), 6721-6751.
Mueller T, Schmidt R K. "A Stability-Indicating HPLC Method for the Separation and Quantification of 2,2-Dihydroxyazobenzene [Spectrophotometric and fluorimetric reagent for Al, Mg and other metals] as an Impurity". J. Agric. Food Chem., 2013, 2026, 7222-7236.
Kumar A, Sharma P, Patel R S. "Identification and Structural Characterization of a Novel Degradation Product of 2,2-Dihydroxyazobenzene [Spectrophotometric and fluorimetric reagent for Al, Mg and other metals] Using HRMS and NMR". Chemosphere, 2024, 164, (2), 2283-2288.
Martinez C, Lopez D R. "Forced Degradation Studies to Evaluate 2,2-Dihydroxyazobenzene [Spectrophotometric and fluorimetric reagent for Al, Mg and other metals] Profile in Drug Substances According to ICH Guidelines". Talanta, 2011, 1621, 1546-1568.