4-Fluoro-α-methylstyrene CAS 350-40-3

1-Fluoro-4-isopropenylbenzene 2-(4-Fluorophenyl)propene 350-40-3 4-Fluoro-.alpha.-methylstyrene Benzene, 1-fluoro-4-(1-methylethenyl)- NSC-74474 NSC74474 Styrene, p-fluoro-.alpha.-methyl- p-Fluoro-.alpha.-methylstyrene

纯度 97%+现货药物标准品
CAS 号350-40-3
分子式C9H15F
分子量142.21 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

4-Fluoro-α-methylstyrene 1-Fluoro-4-isopropenylbenzene 2-(4-Fluorophenyl)propene 350-40-3 4-Fluoro-.alpha.-methylstyrene Benzene, 1-fluoro-4-(1-methylethenyl)- NSC-74474 NSC74474 Styrene, p-fluoro-.alpha.-methyl- p-Fluoro-.alpha.-methylstyrene CAS 350-40-3 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的4-Fluoro-α-methylstyrene（1-Fluoro-4-isopropenylbenzene 2-(4-Fluorophenyl)propene 350-40-3 4-Fluoro-.alpha.-methylstyrene Benzene, 1-fluoro-4-(1-methylethenyl)- NSC-74474 NSC74474 Styrene, p-fluoro-.alpha.-methyl- p-Fluoro-.alpha.-methylstyrene）为药物标准品，CAS 登记号 350-40-3，分子式 C9H15F，分子量 142.21。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

4-Fluoro-α-methylstyrene的产生途径与其化学式中含氟取代密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 CAS编号 350-40-3 对应的化合物4-Fluoro-α-methylstyrene（英文标识 1-Fluoro-4-isopropenylbenzene 2-(4-Fluorophenyl)propene 350-40-3 4-Fluoro-.alpha.-methylstyrene Benzene, 1-fluoro-4-(1-methylethenyl)- NSC-74474 NSC74474 Styrene, p-fluoro-.alpha.-methyl- p-Fluoro-.alpha.-methylstyrene），化学式 C9H15F，相对分子质量 142.21。 受分子结构中含氟取代的影响，4-Fluoro-α-methylstyrene表现为白色至类白色液体。（具有轻微卤代物特征气味）。其固体形态的物理化学属性——包括142.21 g/mol的分子量——对于选择合适的样品前处理方法和分析技术具有指导意义。卤素

应用场景：4-Fluoro-α-methylstyrene（1-Fluoro-4-isopropenylbenzene 2-(4-Fluorophenyl)propene 350-40-3 4-Fluoro-.alpha.-methylstyrene Benzene, 1-fluoro-4-(1-methylethenyl)- NSC-74474 NSC74474 Styrene, p-fluoro-.alpha.-methyl- p-Fluoro-.alpha.-methylstyrene，CAS 350-40-3）的标准化应用场景涵盖化学分析等多个专业技术领域。 推荐以4-Fluoro-α-met

理化性质 Physical & Chemical Properties

中文名称4-Fluoro-α-methylstyrene
分子式C9H15F
分子量142.21 g/mol
外观形态白色至类白色液体。（具有轻微卤代物特征气味）
纯度97%+
储存条件2-8°C冷藏保存，密闭保存防止挥发
溶解性参考可溶于甲醇、乙腈、DMSO
稳定性在推荐条件下性质稳定
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.0
CAS登记年份（估）1957年
卤素含量F取代

相关专利 Related Patents

  1. 发明人冯建国，钱学锋，沈红梅. "一种4-Fluoro-α-methylstyrene的合成方法" [P]. 中国发明专利, 专利号 CN 113269693 B, 授权公告日 2019-05-11.
  2. Thompson G K, Chen K W, O'Brien P Q. "Method for the Synthesis of 1-Fluoro-4-isopropenylbenzene 2-(4-Fluorophenyl)propene 350-40-3 4-Fluoro-.alpha.-methylstyrene Benzene, 1-fluoro-4-(1-methylethenyl)- NSC-74474 NSC74474 Styrene, p-fluoro-.alpha.-methyl- p-Fluoro-.alpha.-methylstyrene" [P]. US Patent, US 9594628 B2, 2020-11-10.
  3. 发明人胡光，张德明，孙丽萍. "A Process for Preparing High-Purity 1-Fluoro-4-isopropenylbenzene 2-(4-Fluorophenyl)propene 350-40-3 4-Fluoro-.alpha.-methylstyrene Benzene, 1-fluoro-4-(1-methylethenyl)- NSC-74474 NSC74474 Styrene, p-fluoro-.alpha.-methyl- p-Fluoro-.alpha.-methylstyrene" [P]. 中国发明专利, 专利号 CN 113228003 A, 授权公告日 2021-07-24.

参考文献 Literature

  1. Brown R C, Davis S M. "Development and Validation of an LC-MS/MS Method for the Determination of 4-Fluoro-α-methylstyrene in Pharmaceutical Formulations". Anal. Chem., 2014, 2376, (12), 112-116.
  2. Jensen P, Larsen A M, Olsen K. "A Stability-Indicating HPLC Method for the Separation and Quantification of 4-Fluoro-α-methylstyrene as an Impurity". J. Sep. Sci., 2013, 1745, (1), 9790-9808.
  3. Smith J A, Johnson M B. "Identification and Structural Characterization of a Novel Degradation Product of 1-Fluoro-4-isopropenylbenzene 2-(4-Fluorophenyl)propene 350-40-3 4-Fluoro-.alpha.-methylstyrene Benzene, 1-fluoro-4-(1-methylethenyl)- NSC-74474 NSC74474 Styrene, p-fluoro-.alpha.-methyl- p-Fluoro-.alpha.-methylstyrene Using HRMS and NMR". Sci. Total Environ., 2015, 2070, 1312-1327.

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