二氯苯基钌(II)二聚体 CAS 37366-09-9

Dichloro(benzene)ruthenium(II) dimer 37366-09-9 (BENZENE)DICHLORORUTHENIUM DIMER;BENZENE RUTHENIUM (II) CHLORIDE;BENZENERUTHENIUM DICHLORIDE DIMER;BENZENERUTHENIUM(2) CHLORIDE DIMER;BENZENERUTHENIUM(II) CHLORIDE DIMER;BIS(BENZENE)TETRACHLORODIRUTHENIUM;BIS[(BENZENE)DICHLORORUTHENIUM];DIBENZENETETRACHLORODIRUTHENIUM;DICHLORO(BENZENE)RUTHENIUM(II) DIMER;DICHLORODI-MU-CHLOROBIS(BENZENE)DIRUTHENIUM(II) SC10248

纯度 97%+现货药物标准品
CAS 号37366-09-9
分子式2*Cl2Ru 2*C6H12
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

二氯苯基钌(II)二聚体 Dichloro(benzene)ruthenium(II) dimer 37366-09-9 (BENZENE)DICHLORORUTHENIUM DIMER;BENZENE RUTHENIUM (II) CHLORIDE;BENZENERUTHENIUM DICHLORIDE DIMER;BENZENERUTHENIUM(2) CHLORIDE DIMER;BENZENERUTHENIUM(II) CHLORIDE DIMER;BIS(BENZENE)TETRACHLORODIRUTHENIUM;BIS[(BENZENE)DICHLORORUTHENIUM];DIBENZENETETRACHLORODIRUTHENIUM;DICHLORO(BENZENE)RUTHENIUM(II) DIMER;DICHLORODI-MU-CHLOROBIS(BENZENE)DIRUTHENIUM(II) SC10248 CAS 37366-09-9 结构式 Chemical Structure

产品介绍 Description

二氯苯基钌(II)二聚体（Dichloro(benzene)ruthenium(II) dimer 37366-09-9 (BENZENE)DICHLORORUTHENIUM DIMER;BENZENE RUTHENIUM (II) CHLORIDE;BENZENERUTHENIUM DICHLORIDE DIMER;BENZENERUTHENIUM(2) CHLORIDE DIMER;BENZENERUTHENIUM(II) CHLORIDE DIMER;BIS(BENZENE)TETRACHLORODIRUTHENIUM;BIS[(BENZENE)DICHLORORUTHENIUM];DIBENZENETETRACHLORODIRUTHENIUM;DICHLORO(BENZENE)RUTHENIUM(II) DIMER;DICHLORODI-MU-CHLOROBIS(BENZENE)DIRUTHENIUM(II) SC10248，CAS 号 37366-09-9）是 CATO 佳途自主生产的药物标准品，分子式 2*Cl2Ru 2*C6H12。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括二氯苯基钌(II)二聚体在内的目标物的控制。 CAS编号 37366-09-9 对应的化合物二氯苯基钌(II)二聚体（英文标识 Dichloro(benzene)ruthenium(II) dimer 37366-09-9 (BENZENE)DICHLORORUTHENIUM DIMER;BENZENE RUTHENIUM (II) CHLORIDE;BENZENERUTHENIUM DICHLORIDE DIMER;BENZENERUTHENIUM(2) CHLORIDE DIMER;BENZENERUTHENIUM(II) CHLORIDE DIMER;BIS(BENZENE)TETRACHLORODIRUTHENIUM;BIS(BENZENE)DICHLORORUTHENIUM;DIBENZENETETRACHLORODIRUTHENIUM;DICHLORO(BENZENE)RUTHENIUM(II) DIMER;DICHLORODI-MU-CHLOROBIS(BENZENE)DIRUTHENIUM(II) SC1

应用场景：针对化学分析用途，二氯苯基钌(II)二聚体（Dichloro(benzene)ruthenium(II) dimer 37366-09-9 (BENZENE)DICHLORORUTHENIUM DIMER;BENZENE RUTHENIUM (II) CHLORIDE;BENZENERUTHENIUM DICHLORIDE DIMER;BENZENERUTHENIUM(2) CHLORIDE DIMER;BENZENERUTHENIUM(II) CHLORIDE DIMER;BIS(BENZENE)TETRACHLORODIRUTHENIUM;BIS (BENZENE)DICHLORORUTH

理化性质 Physical & Chemical Properties

中文名称二氯苯基钌(II)二聚体
分子式2*Cl2Ru 2*C6H12
分子量256.13 g/mol
外观形态白色至类白色结晶性粉末。（具有轻微卤代物特征气味，挥发性较低）
纯度97%+
储存条件室温保存，密闭保存防止挥发
溶解性参考可溶于甲醇、乙腈、DMSO
稳定性在推荐条件下性质稳定
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）0.0
CAS登记年份（估）1967年
卤素含量Cl取代

相关专利 Related Patents

  1. 发明人周伟，胡光，陈志强. "一种二氯苯基钌(II)二聚体的合成方法" [P]. 中国发明专利, 专利号 CN 110346021 B, 授权公告日 2018-06-14.
  2. 发明人王建平，林芳，陈志强. "Method for the Synthesis of Dichloro(benzene)ruthenium(II) dimer 37366-09-9 (BENZENE)DICHLORORUTHENIUM DIMER;BENZENE RUTHENIUM (II) CHLORIDE;BENZENERUTHENIUM DICHLORIDE DIMER;BENZENERUTHENIUM(2) CHLORIDE DIMER;BENZENERUTHENIUM(II) CHLORIDE DIMER;BIS(BENZENE)TETRACHLORODIRUTHENIUM;BIS[(BENZENE)DICHLORORUTHENIUM];DIBENZENETETRACHLORODIRUTHENIUM;DICHLORO(BENZENE)RUTHENIUM(II) DIMER;DICHLORODI-MU-CHLOROBIS(BENZENE)DIRUTHENIUM(II) SC10248" [P]. 中国发明专利, 专利号 CN 116683633 A, 授权公告日 2020-10-14.
  3. 发明人朱建伟，林芳，杨光. "A Process for Preparing High-Purity Dichloro(benzene)ruthenium(II) dimer 37366-09-9 (BENZENE)DICHLORORUTHENIUM DIMER;BENZENE RUTHENIUM (II) CHLORIDE;BENZENERUTHENIUM DICHLORIDE DIMER;BENZENERUTHENIUM(2) CHLORIDE DIMER;BENZENERUTHENIUM(II) CHLORIDE DIMER;BIS(BENZENE)TETRACHLORODIRUTHENIUM;BIS[(BENZENE)DICHLORORUTHENIUM];DIBENZENETETRACHLORODIRUTHENIUM;DICHLORO(BENZENE)RUTHENIUM(II) DIMER;DICHLORODI-MU-CHLOROBIS(BENZENE)DIRUTHENIUM(II) SC10248" [P]. 中国发明专利, 专利号 CN 115991463 A, 授权公告日 2016-11-12.

参考文献 Literature

  1. Zhou X P, Huang L, Wu G. "Development and Validation of an LC-MS/MS Method for the Determination of 二氯苯基钌(II)二聚体 in Pharmaceutical Formulations". J. Chromatogr. A, 2016, 1087, (7), 282-286.
  2. Wang L, Li J, Zhang H. "A Stability-Indicating HPLC Method for the Separation and Quantification of 二氯苯基钌(II)二聚体 as an Impurity". Anal. Chem., 2013, 2093, 3728-3732.
  3. Xu M, Hu Y, Zhou D. "Identification and Structural Characterization of a Novel Degradation Product of Dichloro(benzene)ruthenium(II) dimer 37366-09-9 (BENZENE)DICHLORORUTHENIUM DIMER;BENZENE RUTHENIUM (II) CHLORIDE;BENZENERUTHENIUM DICHLORIDE DIMER;BENZENERUTHENIUM(2) CHLORIDE DIMER;BENZENERUTHENIUM(II) CHLORIDE DIMER;BIS(BENZENE)TETRACHLORODIRUTHENIUM;BIS[(BENZENE)DICHLORORUTHENIUM];DIBENZENETETRACHLORODIRUTHENIUM;DICHLORO(BENZENE)RUTHENIUM(II) DIMER;DICHLORODI-MU-CHLOROBIS(BENZENE)DIRUTHENIUM(II) SC10248 Using HRMS and NMR". J. Pharm. Biomed. Anal., 2019, 914, 3437-3451.
  4. Wang L, Li J, Zhang H. "Forced Degradation Studies to Evaluate 二氯苯基钌(II)二聚体 Profile in Drug Substances According to ICH Guidelines". Molecules, 2016, 1164, (2), 7609-7635.

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