6-Bromo-3-fluoro-2-methylpyridine CAS 374633-38-2

2-BROMO-5-FLUORO-6-METHYLPYRIDINE 2-BROMO-5-FLUORO-6-PICOLINE 2-Bromo-5-fluoro-6-methyl pyridine 374633-38-2 5-FLUORO-6-METHYL-2-BROMOPYRIDINE 6-BROMO-3-FLUORO-2-METHYLPYRIDINE 6-BROMO-3-FLUORO-2-PICOLINE 6-BROMO-3-FLUOROPICOLINE ABBYPHARMA AP-18-5105 LF10368 PYRIDINE, 6-BROMO-3-FLUORO-2-METHYL-

纯度 97%+现货药物标准品
CAS 号374633-38-2
分子式C6H11BrFN
分子量196.06 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

6-Bromo-3-fluoro-2-methylpyridine 2-BROMO-5-FLUORO-6-METHYLPYRIDINE 2-BROMO-5-FLUORO-6-PICOLINE 2-Bromo-5-fluoro-6-methyl pyridine 374633-38-2 5-FLUORO-6-METHYL-2-BROMOPYRIDINE 6-BROMO-3-FLUORO-2-METHYLPYRIDINE 6-BROMO-3-FLUORO-2-PICOLINE 6-BROMO-3-FLUOROPICOLINE ABBYPHARMA AP-18-5105 LF10368 PYRIDINE, 6-BROMO-3-FLUORO-2-METHYL- CAS 374633-38-2 结构式 Chemical Structure

产品介绍 Description

CAS 374633-38-2 对应的6-Bromo-3-fluoro-2-methylpyridine（2-BROMO-5-FLUORO-6-METHYLPYRIDINE 2-BROMO-5-FLUORO-6-PICOLINE 2-Bromo-5-fluoro-6-methyl pyridine 374633-38-2 5-FLUORO-6-METHYL-2-BROMOPYRIDINE 6-BROMO-3-FLUORO-2-METHYLPYRIDINE 6-BROMO-3-FLUORO-2-PICOLINE 6-BROMO-3-FLUOROPICOLINE ABBYPHARMA AP-18-5105 LF10368 PYRIDINE, 6-BROMO-3-FLUORO-2-METHYL-）为 CATO 佳途药物标准品产品线成员。分子式 C6H11BrFN，分子量 196.06。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括6-Bromo-3-fluoro-2-methylpyridine在内的目标物的控制。 化学式为 C6H11BrFN 的6-Bromo-3-fluoro-2-methylpyridine（2-BROMO-5-FLUORO-6-METHYLPYRIDINE 2-BROMO-5-FLUORO-6-PICOLINE 2-Bromo-5-fluoro-6-methyl pyridine 374633-38-2 5-FLUORO-6-METHYL-2-BROMOPYRIDINE 6-BROMO-3-FLUORO-2-METHYLPYRIDINE 6-BROMO-3-FLUORO-2-PICOLINE 6-BROMO-3-FLUOROPICOLINE ABBYPHARMA AP-18-5105 LF10368 PYRIDINE, 6-BROMO-3-FLUORO-2-METHYL-），其CAS登记号是 374633-38-2，分子量为 196.06 g/mol。 从化学结构特征来看，6-Bromo-3-fluoro-2-methylp

应用场景：6-Bromo-3-fluoro-2-methylpyridine（2-BROMO-5-FLUORO-6-METHYLPYRIDINE 2-BROMO-5-FLUORO-6-PICOLINE 2-Bromo-5-fluoro-6-methyl pyridine 374633-38-2 5-FLUORO-6-METHYL-2-BROMOPYRIDINE 6-BROMO-3-FLUORO-2-METHYLPYRIDINE 6-BROMO-3-FLUORO-2-PICOLINE 6-BROMO-3-FLUOROPICOLINE ABBYPHARMA AP-18-5105 LF10368 PYRIDI

理化性质 Physical & Chemical Properties

中文名称6-Bromo-3-fluoro-2-methylpyridine
分子式C6H11BrFN
分子量196.06 g/mol
外观形态白色至类白色结晶性粉末。（具有轻微卤代物特征气味，具有氨/胺类微弱气味，挥发性较低）
纯度97%+
储存条件2-8°C冷藏保存，避光，密闭保存防止挥发
溶解性参考可溶于甲醇、乙腈、DMSO
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）1.0
CAS登记年份（估）2025年
卤素含量F/Br取代
含氮原子数1

相关专利 Related Patents

  1. Thompson G K, Park J H, Fischer A B. "一种6-Bromo-3-fluoro-2-methylpyridine的合成方法" [P]. US Patent, US 10735498 B2, 2019-10-14.
  2. Williams B T, Yamamoto T, Anderson J P. "Method for the Synthesis of 2-BROMO-5-FLUORO-6-METHYLPYRIDINE 2-BROMO-5-FLUORO-6-PICOLINE 2-Bromo-5-fluoro-6-methyl pyridine 374633-38-2 5-FLUORO-6-METHYL-2-BROMOPYRIDINE 6-BROMO-3-FLUORO-2-METHYLPYRIDINE 6-BROMO-3-FLUORO-2-PICOLINE 6-BROMO-3-FLUOROPICOLINE ABBYPHARMA AP-18-5105 LF10368 PYRIDINE, 6-BROMO-3-FLUORO-2-METHYL-" [P]. US Patent, US 10304314 B2, 2015-03-26.

参考文献 Literature

  1. Garcia M, Rodriguez P. "Development and Validation of an LC-MS/MS Method for the Determination of 6-Bromo-3-fluoro-2-methylpyridine in Pharmaceutical Formulations". Chemosphere, 2012, 1579, 9375-9385.
  2. Smith J A, Johnson M B. "A Stability-Indicating HPLC Method for the Separation and Quantification of 6-Bromo-3-fluoro-2-methylpyridine as an Impurity". Biomed. Chromatogr., 2011, 2251, 7721-7741.

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