CP724714 CAS 383432-38-0

383432-38-0 I05QZ0S4V3 CP-724714 UNII-I05QZ0S4V3 2-Methoxy-N-((2E)-3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propen-1-yl)acetamide Acetamide, 2-methoxy-N-(3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propen-1-yl)- CP-724,714

纯度 97%+现货药物标准品
CAS 号383432-38-0
分子式C27H27N5O3
分子量469.53 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

CP724714 383432-38-0 I05QZ0S4V3 CP-724714 UNII-I05QZ0S4V3 2-Methoxy-N-((2E)-3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propen-1-yl)acetamide Acetamide, 2-methoxy-N-(3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propen-1-yl)- CP-724,714 CAS 383432-38-0 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品CP724714（383432-38-0 I05QZ0S4V3 CP-724714 UNII-I05QZ0S4V3 2-Methoxy-N-((2E)-3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propen-1-yl)acetamide Acetamide, 2-methoxy-N-(3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propen-1-yl)- CP-724,714，CAS 383432-38-0），分子式 C27H27N5O3，分子量 469.53。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

作为认证标准物质（CRM），CP724714满足CNAS-CL04（ISO/IEC 17025）对标准物质的计量溯源性要求。批间一致性通过控制图（Control Chart）进行持续监控，保证不同批次间量值的一致性。 CAS编号 383432-38-0 对应的化合物CP724714（英文标识 383432-38-0 I05QZ0S4V3 CP-724714 UNII-I05QZ0S4V3 2-Methoxy-N-((2E)-3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propen-1-yl)acetamide Acetamide, 2-methoxy-N-(3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propen-1-yl)- CP-724,714），化学式 C27H27N5O3，相对分子质量 469.53。 依据分子式为 C27H27N5O3 的C

应用场景：针对化学分析用途，CP724714（383432-38-0 I05QZ0S4V3 CP-724714 UNII-I05QZ0S4V3 2-Methoxy-N-((2E)-3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propen-1-yl)acetamide Acetamide, 2-methoxy-N-(3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propen-1-yl)- C

理化性质 Physical & Chemical Properties

中文名称CP724714
分子式C27H27N5O3
分子量469.53 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）17.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）2025年
含氮原子数5

相关专利 Related Patents

  1. 发明人刘建华，黄志刚，唐晓军. "一种CP724714的合成方法" [P]. 中国发明专利, 专利号 CN 116375848 B, 授权公告日 2016-11-22.
  2. 发明人郭海燕，郑宇鹏，赵玉洁. "Method for the Synthesis of 383432-38-0 I05QZ0S4V3 CP-724714 UNII-I05QZ0S4V3 2-Methoxy-N-((2E)-3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propen-1-yl)acetamide Acetamide, 2-methoxy-N-(3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propen-1-yl)- CP-724,714" [P]. 中国发明专利, 专利号 CN 117260812 A, 授权公告日 2019-07-24.

参考文献 Literature

  1. Zhang Y, Li Q, Chen T. "Development and Validation of an LC-MS/MS Method for the Determination of CP724714 in Pharmaceutical Formulations". J. Agric. Food Chem., 2013, 640, 5397-5424.
  2. Zhou X P, Huang L, Wu G. "A Stability-Indicating HPLC Method for the Separation and Quantification of CP724714 as an Impurity". Sci. Total Environ., 2020, 1115, (2), 8641-8666.
  3. Mueller T, Schmidt R K. "Identification and Structural Characterization of a Novel Degradation Product of 383432-38-0 I05QZ0S4V3 CP-724714 UNII-I05QZ0S4V3 2-Methoxy-N-((2E)-3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propen-1-yl)acetamide Acetamide, 2-methoxy-N-(3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propen-1-yl)- CP-724,714 Using HRMS and NMR". J. Chromatogr. A, 2022, 406, 3775-3788.
  4. Fischer P, Wagner E. "Forced Degradation Studies to Evaluate CP724714 Profile in Drug Substances According to ICH Guidelines". Anal. Methods, 2015, 488, (10), 6313-6341.

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