D-ribo-Phytosphingosine-1-Phosphate CAS 383908-62-1

(2S, 3S, 4R)-2-amino-1,3,4-octadecanetriol-1-phosphate 383908-62-1 4-hydroxysphinganine-1-phosphate (Saccharomyces Cerevisiae) D-ribo-Phytosphingosine-1-Phosphate Phytosphingosine 2S, 3S, 4R-1-Phosphate (Saccharomyces Cerevisiae)

纯度 97%+现货药物标准品
CAS 号383908-62-1
分子式C18H40NO6P
分子量397.49 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

D-ribo-Phytosphingosine-1-Phosphate (2S, 3S, 4R)-2-amino-1,3,4-octadecanetriol-1-phosphate 383908-62-1 4-hydroxysphinganine-1-phosphate (Saccharomyces Cerevisiae) D-ribo-Phytosphingosine-1-Phosphate Phytosphingosine 2S, 3S, 4R-1-Phosphate (Saccharomyces Cerevisiae) CAS 383908-62-1 结构式 Chemical Structure

产品介绍 Description

D-ribo-Phytosphingosine-1-Phosphate（(2S, 3S, 4R)-2-amino-1,3,4-octadecanetriol-1-phosphate 383908-62-1 4-hydroxysphinganine-1-phosphate (Saccharomyces Cerevisiae) D-ribo-Phytosphingosine-1-Phosphate Phytosphingosine 2S, 3S, 4R-1-Phosphate (Saccharomyces Cerevisiae)）是药物分析与质量控制领域常用的药物标准品，CAS 号 383908-62-1。分子式 C18H40NO6P，分子量 397.49。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

推荐用于分析方法开发与验证，产品提供完整COA证书，确保ISO 17034标准的量值溯源要求。适用于GLP实验室的日常分析。 D-ribo-Phytosphingosine-1-Phosphate（(2S, 3S, 4R)-2-amino-1,3,4-octadecanetriol-1-phosphate 383908-62-1 4-hydroxysphinganine-1-phosphate (Saccharomyces Cerevisiae) D-ribo-Phytosphingosine-1-Phosphate Phytosphingosine 2S, 3S, 4R-1-Phosphate (Saccharomyces Cerevisiae)），CAS注册编号 383908-62-1，化学分子式为 C18H40NO6P，分子量 397.49 g/mol。 受分子结构中酰胺类，含磷酸酯基，羧酸类，含羟基，含醚键的影响，D-ribo-Phytosphingosine-1-Phosphate表现为白色至类白色结晶性粉末。其固体形态的物理化学属性——包括397.49

应用场景：从实际应用出发，D-ribo-Phytosphingosine-1-Phosphate（CAS 383908-62-1）在化学分析中作为关键的基准对照物质。 推荐以D-ribo-Phytosphingosine-1-Phosphate配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈（1:1）为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用甲醇/乙腈（1:1）配制，于2-8°C冷藏保存，避光，密封防潮条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜

理化性质 Physical & Chemical Properties

中文名称D-ribo-Phytosphingosine-1-Phosphate
分子式C18H40NO6P
分子量397.49 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）-0.5
CAS登记年份（估）2025年
含氮原子数1

相关专利 Related Patents

  1. Johnson M A, Klinger H, Brown S R. "一种D-ribo-Phytosphingosine-1-Phosphate的合成方法" [P]. US Patent, US 10086268 B2, 2022-06-26.
  2. 发明人郑宇鹏，周伟，马晓峰. "Method for the Synthesis of (2S, 3S, 4R)-2-amino-1,3,4-octadecanetriol-1-phosphate 383908-62-1 4-hydroxysphinganine-1-phosphate (Saccharomyces Cerevisiae) D-ribo-Phytosphingosine-1-Phosphate Phytosphingosine 2S, 3S, 4R-1-Phosphate (Saccharomyces Cerevisiae)" [P]. 中国发明专利, 专利号 CN 108397034 A, 授权公告日 2023-10-22.
  3. 发明人李文辉，钱学锋，陈志强. "A Process for Preparing High-Purity (2S, 3S, 4R)-2-amino-1,3,4-octadecanetriol-1-phosphate 383908-62-1 4-hydroxysphinganine-1-phosphate (Saccharomyces Cerevisiae) D-ribo-Phytosphingosine-1-Phosphate Phytosphingosine 2S, 3S, 4R-1-Phosphate (Saccharomyces Cerevisiae)" [P]. 中国发明专利, 专利号 CN 117673112 A, 授权公告日 2023-07-15.

参考文献 Literature

  1. Wang L, Li J, Zhang H. "Development and Validation of an LC-MS/MS Method for the Determination of D-ribo-Phytosphingosine-1-Phosphate in Pharmaceutical Formulations". Food Chem., 2017, 2037, (10), 1136-1147.
  2. Wang L, Li J, Zhang H. "A Stability-Indicating HPLC Method for the Separation and Quantification of D-ribo-Phytosphingosine-1-Phosphate as an Impurity". Sci. Total Environ., 2010, 341, (6), 4536-4566.
  3. Chen X Y, Liu M, Zhao W Q. "Identification and Structural Characterization of a Novel Degradation Product of (2S, 3S, 4R)-2-amino-1,3,4-octadecanetriol-1-phosphate 383908-62-1 4-hydroxysphinganine-1-phosphate (Saccharomyces Cerevisiae) D-ribo-Phytosphingosine-1-Phosphate Phytosphingosine 2S, 3S, 4R-1-Phosphate (Saccharomyces Cerevisiae) Using HRMS and NMR". Chemosphere, 2019, 949, (2), 2792-2795.
  4. Zhang Y, Li Q, Chen T. "Forced Degradation Studies to Evaluate D-ribo-Phytosphingosine-1-Phosphate Profile in Drug Substances According to ICH Guidelines". Molecules, 2018, 1994, (4), 8033-8049.

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