三羟甲丙烷三聚丙二醇醚(氨基封端) CAS 39423-51-3

39423-51-3 Poly(oxy(methyl-1,2-ethanediyl)), alpha-hydro-omega-(2-aminomethylethoxy)-, ether with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol (3:1) Propylidynetrimethanol, propoxylated, reaction products with Ammonia Trimethylolpropane poly(oxypropylene)triamine EC 500-105-6

纯度 97%+现货药物标准品
CAS 号39423-51-3
分子式C6H14O3 C3H8O2 C3H9NO
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

三羟甲丙烷三聚丙二醇醚(氨基封端) 39423-51-3 Poly(oxy(methyl-1,2-ethanediyl)), alpha-hydro-omega-(2-aminomethylethoxy)-, ether with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol (3:1) Propylidynetrimethanol, propoxylated, reaction products with Ammonia Trimethylolpropane poly(oxypropylene)triamine EC 500-105-6 CAS 39423-51-3 结构式 Chemical Structure

产品介绍 Description

三羟甲丙烷三聚丙二醇醚(氨基封端)（英文名 39423-51-3 Poly(oxy(methyl-1,2-ethanediyl)), alpha-hydro-omega-(2-aminomethylethoxy)-, ether with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol (3:1) Propylidynetrimethanol, propoxylated, reaction products with Ammonia Trimethylolpropane poly(oxypropylene)triamine EC 500-105-6，CAS 39423-51-3）属于药物标准品。分子式 C6H14O3 C3H8O2 C3H9NO。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

化学式为 C6H14O3 C3H8O2 C3H9NO 的三羟甲丙烷三聚丙二醇醚(氨基封端)（39423-51-3 Poly(oxy(methyl-1,2-ethanediyl)), alpha-hydro-omega-(2-aminomethylethoxy)-, ether with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol (3:1) Propylidynetrimethanol, propoxylated, reaction products with Ammonia Trimethylolpropane poly(oxypropylene)triamine EC 500-105-6），其CAS登记号是 39423-51-3，分子量为 285.38 g/mol。 三羟甲丙烷三聚丙二醇醚(氨基封端)（分子式 C6H14O3 C3H8O2 C3H9NO）的化学结构中包含氨基酸衍生物，酰胺类，含羟基，含醚键。在反相色谱体系中，其保留行为主要受含氮官能团的质子化状态影响，这为HPLC-UV/DAD或LC-MS方法的建立提供了重要依据。分子中的氮

应用场景：三羟甲丙烷三聚丙二醇醚(氨基封端)（39423-51-3 Poly(oxy(methyl-1,2-ethanediyl)), alpha-hydro-omega-(2-aminomethylethoxy)-, ether with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol (3:1) Propylidynetrimethanol, propoxylated, reaction products with Ammonia Trimethylolpropane poly(oxypropylene)triamine EC 500-105-6，CAS 3942

理化性质 Physical & Chemical Properties

中文名称三羟甲丙烷三聚丙二醇醚(氨基封端)
分子式C6H14O3 C3H8O2 C3H9NO
分子量285.38 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）-2.0
CAS登记年份（估）1968年
含氮原子数1

相关专利 Related Patents

  1. 发明人朱建伟，杨光，沈红梅. "一种三羟甲丙烷三聚丙二醇醚(氨基封端)的合成方法" [P]. 中国发明专利, 专利号 CN 114275823 A, 授权公告日 2020-11-10.
  2. 发明人刘建华，唐晓军，罗永刚. "Method for the Synthesis of 39423-51-3 Poly(oxy(methyl-1,2-ethanediyl)), alpha-hydro-omega-(2-aminomethylethoxy)-, ether with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol (3:1) Propylidynetrimethanol, propoxylated, reaction products with Ammonia Trimethylolpropane poly(oxypropylene)triamine EC 500-105-6" [P]. 中国发明专利, 专利号 CN 117723279 B, 授权公告日 2018-05-20.

参考文献 Literature

  1. Hughes D, Roberts J, Thomas A. "Development and Validation of an LC-MS/MS Method for the Determination of 三羟甲丙烷三聚丙二醇醚(氨基封端) in Pharmaceutical Formulations". J. Sep. Sci., 2018, 1901, 39-59.
  2. Mueller T, Schmidt R K. "A Stability-Indicating HPLC Method for the Separation and Quantification of 三羟甲丙烷三聚丙二醇醚(氨基封端) as an Impurity". J. Chromatogr. A, 2019, 2226, 8319-8336.
  3. Fischer P, Wagner E. "Identification and Structural Characterization of a Novel Degradation Product of 39423-51-3 Poly(oxy(methyl-1,2-ethanediyl)), alpha-hydro-omega-(2-aminomethylethoxy)-, ether with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol (3:1) Propylidynetrimethanol, propoxylated, reaction products with Ammonia Trimethylolpropane poly(oxypropylene)triamine EC 500-105-6 Using HRMS and NMR". Biomed. Chromatogr., 2018, 1042, (6), 5050-5062.

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