1-(4-氟苯基)乙醇 CAS 403-41-8

1-(4'-Fluorophenyl)-1-hydroxyethane 1-(4-FLUOROPHENYL)-1-ETHANOL 1-(4-FLUOROPHENYL)ETHAN-1-OL 1-(4-FLUOROPHENYL)ETHANOL 1-(P-FLUOROPHENYL)ETHANOL 4-FLUORO-ALPHA-METHYLBENZYL ALCOHOL 4-FLUOROMETHYL-ALPHA-METHYLBENZYL ALCOHOL 4-FLUOROPHENYL METHYL CARBINOL 403-41-8 ALPHA-METHYL-4-FLUOROBENZYL ALCOHOL AS00895 OTAVA-BB 1366693 P-FLUORO-A-METHYLBENZYL ALCOHOL P-FLUORO-ALPHA-METHYLBENZYL ALCOHOL P-FLUOROPHENYLMETHYLCARBINOL

纯度 97%+现货药物标准品

CAS 号	403-41-8
分子式	C8H15FO
分子量	146.20 g/mol
分类	药物标准品 / 原料药标准品
库存状态	现货

化学结构式 Structure

1-(4-氟苯基)乙醇 1-(4'-Fluorophenyl)-1-hydroxyethane
1-(4-FLUOROPHENYL)-1-ETHANOL
1-(4-FLUOROPHENYL)ETHAN-1-OL
1-(4-FLUOROPHENYL)ETHANOL
1-(P-FLUOROPHENYL)ETHANOL
4-FLUORO-ALPHA-METHYLBENZYL ALCOHOL
4-FLUOROMETHYL-ALPHA-METHYLBENZYL ALCOHOL
4-FLUOROPHENYL METHYL CARBINOL
403-41-8
ALPHA-METHYL-4-FLUOROBENZYL ALCOHOL
AS00895
OTAVA-BB 1366693
P-FLUORO-A-METHYLBENZYL ALCOHOL
P-FLUORO-ALPHA-METHYLBENZYL ALCOHOL
P-FLUOROPHENYLMETHYLCARBINOL CAS 403-41-8 结构式 Chemical Structure

产品介绍 Description

1-(4-氟苯基)乙醇（英文名 1-(4'-Fluorophenyl)-1-hydroxyethane 1-(4-FLUOROPHENYL)-1-ETHANOL 1-(4-FLUOROPHENYL)ETHAN-1-OL 1-(4-FLUOROPHENYL)ETHANOL 1-(P-FLUOROPHENYL)ETHANOL 4-FLUORO-ALPHA-METHYLBENZYL ALCOHOL 4-FLUOROMETHYL-ALPHA-METHYLBENZYL ALCOHOL 4-FLUOROPHENYL METHYL CARBINOL 403-41-8 ALPHA-METHYL-4-FLUOROBENZYL ALCOHOL AS00895 OTAVA-BB 1366693 P-FLUORO-A-METHYLBENZYL ALCOHOL P-FLUORO-ALPHA-METHYLBENZYL ALCOHOL P-FLUOROPHENYLMETHYLCARBINOL，CAS 403-41-8）属于药物标准品。分子式 C8H15FO，分子量 146.20。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括1-(4-氟苯基)乙醇在内的目标物的控制。 1-(4-氟苯基)乙醇（1-(4'-Fluorophenyl)-1-hydroxyethane 1-(4-FLUOROPHENYL)-1-ETHANOL 1-(4-FLUOROPHENYL)ETHAN-1-OL 1-(4-FLUOROPHENYL)ETHANOL 1-(P-FLUOROPHENYL)ETHANOL 4-FLUORO-ALPHA-METHYLBENZYL ALCOHOL 4-FLUOROMETHYL-ALPHA-METHYLBENZYL ALCOHOL 4-FLUOROPHENYL METHYL CARBINOL 403-41-8 ALPHA-METHYL-4-FLUOROBENZYL ALCOHOL AS00895 OTAVA-BB 1366693 P-FLUORO-A-METHYLBENZYL ALCOHOL P-FLUORO-ALPHA-METHYLBENZYL ALCOHOL P-FLUOROPHENYLMETHYLCARBINOL），CAS注册编号 403-

应用场景：从实际应用出发，1-(4-氟苯基)乙醇（CAS 403-41-8）在化学分析中作为关键的基准对照物质。推荐以1-(4-氟苯基)乙醇配制标准系列工作溶液，用于建立标准曲线实现外标法定量。建议使用甲醇为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用甲醇配制，于2-8°C冷藏保存，密闭保存防止挥发条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用，防止吸潮影响称量准确性。

理化性质 Physical & Chemical Properties

中文名称	1-(4-氟苯基)乙醇
分子式	C8H15FO
分子量	146.20 g/mol
外观形态	白色至类白色液体。（具有轻微卤代物特征气味）
纯度	97%+
储存条件	2-8°C冷藏保存，密闭保存防止挥发
溶解性参考	可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性	在推荐条件下性质稳定
化合物类型	药物标准品
子类	原料药标准品
不饱和度（DBE）	1.0
CAS登记年份（估）	1957年
卤素含量	F取代

参考文献 Literature

Lee J H, Choi Y S. "Development and Validation of an LC-MS/MS Method for the Determination of 1-(4-氟苯基)乙醇 in Pharmaceutical Formulations". Molecules, 2010, 1455, (11), 8247-8258.
Brown R C, Davis S M. "A Stability-Indicating HPLC Method for the Separation and Quantification of 1-(4-氟苯基)乙醇 as an Impurity". J. Agric. Food Chem., 2019, 1158, (7), 2776-2798.
Yang F, Sun W, Liu J. "Identification and Structural Characterization of a Novel Degradation Product of 1-(4'-Fluorophenyl)-1-hydroxyethane 1-(4-FLUOROPHENYL)-1-ETHANOL 1-(4-FLUOROPHENYL)ETHAN-1-OL 1-(4-FLUOROPHENYL)ETHANOL 1-(P-FLUOROPHENYL)ETHANOL 4-FLUORO-ALPHA-METHYLBENZYL ALCOHOL 4-FLUOROMETHYL-ALPHA-METHYLBENZYL ALCOHOL 4-FLUOROPHENYL METHYL CARBINOL 403-41-8 ALPHA-METHYL-4-FLUOROBENZYL ALCOHOL AS00895 OTAVA-BB 1366693 P-FLUORO-A-METHYLBENZYL ALCOHOL P-FLUORO-ALPHA-METHYLBENZYL ALCOHOL P-FLUOROPHENYLMETHYLCARBINOL Using HRMS and NMR". J. Chromatogr. A, 2013, 2220, (4), 3676-3702.
Kim S H, Park J Y. "Forced Degradation Studies to Evaluate 1-(4-氟苯基)乙醇 Profile in Drug Substances According to ICH Guidelines". Anal. Chem., 2025, 755, 6928-6937.

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