Sphinganine-1-Phosphate (d20:0) CAS 436846-91-2

436846-91-2 D-erythro-sphinganine-1-phosphate (C20 base) Sphinganine-1-Phosphate (d20:0) dihydro-D-erythro-sphingosine-1-phosphate (C20 base) sphinganine-1-phosphate (C20 base)

纯度 97%+现货药物标准品
CAS 号436846-91-2
分子式C20H44NO5P
分子量409.54 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

Sphinganine-1-Phosphate (d20:0) 436846-91-2 D-erythro-sphinganine-1-phosphate (C20 base) Sphinganine-1-Phosphate (d20:0) dihydro-D-erythro-sphingosine-1-phosphate (C20 base) sphinganine-1-phosphate (C20 base) CAS 436846-91-2 结构式 Chemical Structure

产品介绍 Description

Sphinganine-1-Phosphate (d20:0)（英文名 436846-91-2 D-erythro-sphinganine-1-phosphate (C20 base) Sphinganine-1-Phosphate (d20:0) dihydro-D-erythro-sphingosine-1-phosphate (C20 base) sphinganine-1-phosphate (C20 base)，CAS 436846-91-2）属于药物标准品。分子式 C20H44NO5P，分子量 409.54。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

与同类药物标准品相比，Sphinganine-1-Phosphate (d20:0)的分子量为409.54 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 化学式为 C20H44NO5P 的Sphinganine-1-Phosphate (d20:0)（436846-91-2 D-erythro-sphinganine-1-phosphate (C20 base) Sphinganine-1-Phosphate (d20:0) dihydro-D-erythro-sphingosine-1-phosphate (C20 base) sphinganine-1-phosphate (C20 base)），其CAS登记号是 436846-91-2，分子量为 409.54 g/mol。 依据分子式为 C20H44NO5P 的Sphinganine-1-Phosphate (d20:0)结构特征，其分子内含酰胺类，含磷酸酯基，羧酸类，含羟基，含醚键，这意味着该化合物在红外光谱中会呈现特征性的官能团伸缩振动信号。分子量 409.54 g/mol 这一参数对质谱检测中的分

应用场景：Sphinganine-1-Phosphate (d20:0)（436846-91-2 D-erythro-sphinganine-1-phosphate (C20 base) Sphinganine-1-Phosphate (d20:0) dihydro-D-erythro-sphingosine-1-phosphate (C20 base) sphinganine-1-phosphate (C20 base)）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐以Sphinganine-1-Phosphate (d20:0)配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建

理化性质 Physical & Chemical Properties

中文名称Sphinganine-1-Phosphate (d20:0)
分子式C20H44NO5P
分子量409.54 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件室温保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）-0.5
CAS登记年份（估）2025年
含氮原子数1

相关专利 Related Patents

  1. 发明人赵玉洁，何建平，王建平. "一种Sphinganine-1-Phosphate (d20:0)的合成方法" [P]. 中国发明专利, 专利号 CN 116602326 B, 授权公告日 2019-09-27.
  2. Thompson G K, Roberts E F, Park J H. "Method for the Synthesis of 436846-91-2 D-erythro-sphinganine-1-phosphate (C20 base) Sphinganine-1-Phosphate (d20:0) dihydro-D-erythro-sphingosine-1-phosphate (C20 base) sphinganine-1-phosphate (C20 base)" [P]. US Patent, US 10106583 B2, 2019-02-03.

参考文献 Literature

  1. O'Brien K, Kennedy M L. "Development and Validation of an LC-MS/MS Method for the Determination of Sphinganine-1-Phosphate (d20:0) in Pharmaceutical Formulations". J. Pharm. Biomed. Anal., 2016, 1825, (10), 5397-5417.
  2. Jensen P, Larsen A M, Olsen K. "A Stability-Indicating HPLC Method for the Separation and Quantification of Sphinganine-1-Phosphate (d20:0) as an Impurity". Food Chem., 2018, 757, 6569-6593.
  3. Garcia M, Rodriguez P. "Identification and Structural Characterization of a Novel Degradation Product of 436846-91-2 D-erythro-sphinganine-1-phosphate (C20 base) Sphinganine-1-Phosphate (d20:0) dihydro-D-erythro-sphingosine-1-phosphate (C20 base) sphinganine-1-phosphate (C20 base) Using HRMS and NMR". J. Agric. Food Chem., 2012, 2369, 2944-2974.
  4. Garcia M, Rodriguez P. "Forced Degradation Studies to Evaluate Sphinganine-1-Phosphate (d20:0) Profile in Drug Substances According to ICH Guidelines". Biomed. Chromatogr., 2016, 1238, (2), 4060-4070.

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