氯氮卓 盐酸盐 CAS 438-41-5

MFM6K1XWDK 438-41-5 Chlordiazepoxide hydrochloride [USAN:USP:BAN:JAN] Librax 3H-1,4-Benzodiazepin-2-amine, 7-chloro-N-methyl-5-phenyl-, 4-oxide, monohydrochloride 3H-1,4-Benzodiazepine, 7-chloro-2-methylamino-5-phenyl-, 4-oxide, monohydrochloride Chlordiazepoxide hydrochloride Ansiacal Benzodiapin Calmoden Cebrum Chlordiazachel Chlordiazepoksid Chlordiazepoxide monohydrochloride Chlorodiazepoxide hydrochloride 7-Chloro-2-(methylamino)-5-phenyl-3H-1,4-benzodiazepine 4-oxide monohydrochloride Clopoxide chloride Diazachel (Obs.) Droxol hydrochloride EINECS 207-117-8 Equibral Labican Lentotran J-Liberty Libritabs hydrochloride Librium Librium hydrochloride Methaminodiazepoxide hydrochloride Murcil Napoton hydrochloride Novosed NSC 115748 A-Poxide Protensin Psichial Reliberan Retcol Risachief hydrochloride Ro 5-0690 Seren vita Sophiamin Tensinyl Timosin Trakipeal Viansin Contol Lygen Chlordiazepoxide HCl UNII-MFM6K1XWDK sk-Lygen DEA No. 2744

纯度 97%+现货药物标准品
CAS 号438-41-5
分子式C16H26ClN3O HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

氯氮卓 盐酸盐 MFM6K1XWDK 438-41-5 Chlordiazepoxide hydrochloride [USAN:USP:BAN:JAN] Librax 3H-1,4-Benzodiazepin-2-amine, 7-chloro-N-methyl-5-phenyl-, 4-oxide, monohydrochloride 3H-1,4-Benzodiazepine, 7-chloro-2-methylamino-5-phenyl-, 4-oxide, monohydrochloride Chlordiazepoxide hydrochloride Ansiacal Benzodiapin Calmoden Cebrum Chlordiazachel Chlordiazepoksid Chlordiazepoxide monohydrochloride Chlorodiazepoxide hydrochloride 7-Chloro-2-(methylamino)-5-phenyl-3H-1,4-benzodiazepine 4-oxide monohydrochloride Clopoxide chloride Diazachel (Obs.) Droxol hydrochloride EINECS 207-117-8 Equibral Labican Lentotran J-Liberty Libritabs hydrochloride Librium Librium hydrochloride Methaminodiazepoxide hydrochloride Murcil Napoton hydrochloride Novosed NSC 115748 A-Poxide Protensin Psichial Reliberan Retcol Risachief hydrochloride Ro 5-0690 Seren vita Sophiamin Tensinyl Timosin Trakipeal Viansin Contol Lygen Chlordiazepoxide HCl UNII-MFM6K1XWDK sk-Lygen DEA No. 2744 CAS 438-41-5 结构式 Chemical Structure

产品介绍 Description

氯氮卓 盐酸盐（MFM6K1XWDK 438-41-5 Chlordiazepoxide hydrochloride [USAN:USP:BAN:JAN] Librax 3H-1,4-Benzodiazepin-2-amine, 7-chloro-N-methyl-5-phenyl-, 4-oxide, monohydrochloride 3H-1,4-Benzodiazepine, 7-chloro-2-methylamino-5-phenyl-, 4-oxide, monohydrochloride Chlordiazepoxide hydrochloride Ansiacal Benzodiapin Calmoden Cebrum Chlordiazachel Chlordiazepoksid Chlordiazepoxide monohydrochloride Chlorodiazepoxide hydrochloride 7-Chloro-2-(methylamino)-5-phenyl-3H-1,4-benzodiazepine 4-oxide monohydrochloride Clopoxide chloride Diazachel (Obs.) Droxol hydrochloride EINECS 207-117-8 Equibral Labican Lentotran J-Liberty Libritabs hydrochloride Librium Librium hydrochloride Methaminodiazepoxide hydrochloride Murcil Napoton hydrochloride Novosed NSC 115748 A-Poxide Protensin Psichial Reliberan Retcol Risachief hydrochloride Ro 5-0690 Seren vita Sophiamin Tensinyl Timosin Trakipeal Viansin Contol Lygen Chlordiazepoxide HCl UNII-MFM6K1XWDK sk-Lygen DEA No. 2744）是药物分析与质量控制领域常用的药物标准品，CAS 号 438-41-5。分子式 C16H26ClN3O HCl。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

氯氮卓 盐酸盐（分子式 C16H26ClN3O HCl）的化学结构中包含含氮杂环结构，酰胺类，含羟基，含醚键，含氯取代。在反相色谱体系中，其保留行为主要受其较高的疏水性（logP）影响，这为HPLC-UV/DAD或LC-MS方法的建立提供了重要依据。较高的碳氢原子比赋予该化合物良好的脂溶性，可使用正己烷或乙酸乙酯等非极性溶剂进行液-液萃取前处理。 CAS编号 438-41-5 对应的化合物氯氮卓 盐酸盐（英文标识 MFM6K1XWDK 438-41-5 Chlordiazepoxide hydrochloride USAN:USP:BAN:JAN Librax 3H-1,4-Benzodiazepin-2-amine, 7-chloro-N-methyl-5-phenyl-, 4-oxide, monohydrochloride 3H-1,4-Benzodiazepine, 7-chloro-2-methylamino-5-phenyl-, 4-oxide, monohydrochloride Chlordiazepoxide hydrochloride Ansiacal Ben

应用场景：针对化学分析用途，氯氮卓 盐酸盐（MFM6K1XWDK 438-41-5 Chlordiazepoxide hydrochloride USAN:USP:BAN:JAN Librax 3H-1,4-Benzodiazepin-2-amine, 7-chloro-N-methyl-5-phenyl-, 4-oxide, monohydrochloride 3H-1,4-Benzodiazepine, 7-chloro-2-methylamino-5-phenyl-, 4-oxide, monohydrochloride Chlordiazepoxide hydrochloride Ansia

理化性质 Physical & Chemical Properties

中文名称氯氮卓 盐酸盐
分子式C16H26ClN3O HCl
分子量348.31 g/mol
外观形态类白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味，挥发性较低）
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）4.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1957年
卤素含量Cl取代
含氮原子数3

相关专利 Related Patents

  1. 发明人徐明华，罗永刚，郑宇鹏. "一种氯氮卓 盐酸盐的合成方法" [P]. 中国发明专利, 专利号 CN 110289933 B, 授权公告日 2016-01-03.
  2. Anderson J P, Lee S K, Brown S R. "Method for the Synthesis of MFM6K1XWDK 438-41-5 Chlordiazepoxide hydrochloride [USAN:USP:BAN:JAN] Librax 3H-1,4-Benzodiazepin-2-amine, 7-chloro-N-methyl-5-phenyl-, 4-oxide, monohydrochloride 3H-1,4-Benzodiazepine, 7-chloro-2-methylamino-5-phenyl-, 4-oxide, monohydrochloride Chlordiazepoxide hydrochloride Ansiacal Benzodiapin Calmoden Cebrum Chlordiazachel Chlordiazepoksid Chlordiazepoxide monohydrochloride Chlorodiazepoxide hydrochloride 7-Chloro-2-(methylamino)-5-phenyl-3H-1,4-benzodiazepine 4-oxide monohydrochloride Clopoxide chloride Diazachel (Obs.) Droxol hydrochloride EINECS 207-117-8 Equibral Labican Lentotran J-Liberty Libritabs hydrochloride Librium Librium hydrochloride Methaminodiazepoxide hydrochloride Murcil Napoton hydrochloride Novosed NSC 115748 A-Poxide Protensin Psichial Reliberan Retcol Risachief hydrochloride Ro 5-0690 Seren vita Sophiamin Tensinyl Timosin Trakipeal Viansin Contol Lygen Chlordiazepoxide HCl UNII-MFM6K1XWDK sk-Lygen DEA No. 2744" [P]. US Patent, US 11373353 B2, 2025-12-02.
  3. 发明人郑宇鹏，陈志强，周伟. "A Process for Preparing High-Purity MFM6K1XWDK 438-41-5 Chlordiazepoxide hydrochloride [USAN:USP:BAN:JAN] Librax 3H-1,4-Benzodiazepin-2-amine, 7-chloro-N-methyl-5-phenyl-, 4-oxide, monohydrochloride 3H-1,4-Benzodiazepine, 7-chloro-2-methylamino-5-phenyl-, 4-oxide, monohydrochloride Chlordiazepoxide hydrochloride Ansiacal Benzodiapin Calmoden Cebrum Chlordiazachel Chlordiazepoksid Chlordiazepoxide monohydrochloride Chlorodiazepoxide hydrochloride 7-Chloro-2-(methylamino)-5-phenyl-3H-1,4-benzodiazepine 4-oxide monohydrochloride Clopoxide chloride Diazachel (Obs.) Droxol hydrochloride EINECS 207-117-8 Equibral Labican Lentotran J-Liberty Libritabs hydrochloride Librium Librium hydrochloride Methaminodiazepoxide hydrochloride Murcil Napoton hydrochloride Novosed NSC 115748 A-Poxide Protensin Psichial Reliberan Retcol Risachief hydrochloride Ro 5-0690 Seren vita Sophiamin Tensinyl Timosin Trakipeal Viansin Contol Lygen Chlordiazepoxide HCl UNII-MFM6K1XWDK sk-Lygen DEA No. 2744" [P]. 中国发明专利, 专利号 CN 109069040 A, 授权公告日 2016-12-21.

参考文献 Literature

  1. Chen X Y, Liu M, Zhao W Q. "Development and Validation of an LC-MS/MS Method for the Determination of 氯氮卓 盐酸盐 in Pharmaceutical Formulations". Chemosphere, 2012, 437, 6710-6715.
  2. Hughes D, Roberts J, Thomas A. "A Stability-Indicating HPLC Method for the Separation and Quantification of 氯氮卓 盐酸盐 as an Impurity". Molecules, 2018, 2231, 937-955.

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