CX41 CAS 444910-17-2

Dichloro(di--chloro)bis[1,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene]dipalladium(II) 444910-17-2 CX 41;DICHLORO(DI-MU-CHLORO)BIS[1,3-BIS(2,6-DI-I-PROPYLPHENYL)IMIDAZOL-2-YLIDENE]DIPALLADIUM(II);DICHLORO[1,3-BIS(2,6-DIISOPROPYLPHENYL)-1,3-DIHYDRO-2H-IMIDAZOL-2-YLIDENE]PALLADIUM(II) DIMER;DICHLORO[1,3-BIS(2,6-DIISOPROPYLPHENYL)IMIDAZOLE-2-YLIDENE]PALLADIUM(II) DIMER;DICHLORO[1,3-BIS(DIISOPROPYLPHENYL)-2-IMIDAZOLIDINYLIDENE]PALLADIUM(II) DIMER;DICHLORO[1,3-BIS(DIISOPROPYLPHENYL)IMIDAZOLE-2-YLIDENE]PALLADIUM(II)DIMER;UMICORE CX41;[(SIPR)PDCL2]2;Dichloro(di--chloro)bis[1,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene]dipalladium(II) SC10449

纯度 97%+现货药物标准品
CAS 号444910-17-2
分子式2*C27H48Cl2N2Pd
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

CX41 Dichloro(di--chloro)bis[1,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene]dipalladium(II) 444910-17-2 CX 41;DICHLORO(DI-MU-CHLORO)BIS[1,3-BIS(2,6-DI-I-PROPYLPHENYL)IMIDAZOL-2-YLIDENE]DIPALLADIUM(II);DICHLORO[1,3-BIS(2,6-DIISOPROPYLPHENYL)-1,3-DIHYDRO-2H-IMIDAZOL-2-YLIDENE]PALLADIUM(II) DIMER;DICHLORO[1,3-BIS(2,6-DIISOPROPYLPHENYL)IMIDAZOLE-2-YLIDENE]PALLADIUM(II) DIMER;DICHLORO[1,3-BIS(DIISOPROPYLPHENYL)-2-IMIDAZOLIDINYLIDENE]PALLADIUM(II) DIMER;DICHLORO[1,3-BIS(DIISOPROPYLPHENYL)IMIDAZOLE-2-YLIDENE]PALLADIUM(II)DIMER;UMICORE CX41;[(SIPR)PDCL2]2;Dichloro(di--chloro)bis[1,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene]dipalladium(II) SC10449 CAS 444910-17-2 结构式 Chemical Structure

产品介绍 Description

CX41（Dichloro(di--chloro)bis[1,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene]dipalladium(II) 444910-17-2 CX 41;DICHLORO(DI-MU-CHLORO)BIS[1,3-BIS(2,6-DI-I-PROPYLPHENYL)IMIDAZOL-2-YLIDENE]DIPALLADIUM(II);DICHLORO[1,3-BIS(2,6-DIISOPROPYLPHENYL)-1,3-DIHYDRO-2H-IMIDAZOL-2-YLIDENE]PALLADIUM(II) DIMER;DICHLORO[1,3-BIS(2,6-DIISOPROPYLPHENYL)IMIDAZOLE-2-YLIDENE]PALLADIUM(II) DIMER;DICHLORO[1,3-BIS(DIISOPROPYLPHENYL)-2-IMIDAZOLIDINYLIDENE]PALLADIUM(II) DIMER;DICHLORO[1,3-BIS(DIISOPROPYLPHENYL)IMIDAZOLE-2-YLIDENE]PALLADIUM(II)DIMER;UMICORE CX41;[(SIPR)PDCL2]2;Dichloro(di--chloro)bis[1,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene]dipalladium(II) SC10449）是药物分析与质量控制领域常用的药物标准品，CAS 号 444910-17-2。分子式 2*C27H48Cl2N2Pd。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括CX41在内的目标物的控制。 CAS编号 444910-17-2 对应的化合物CX41（英文标识 Dichloro(di--chloro)bis1,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidenedipalladium(II) 444910-17-2 CX 41;DICHLORO(DI-MU-CHLORO)BIS1,3-BIS(2,6-DI-I-PROPYLPHENYL)IMIDAZOL-2-YLIDENEDIPALLADIUM(II);DICHLORO1,3-BIS(2,6-DIISOPROPYLPHENYL)-1,3-DIHYDRO-2H-IMIDAZOL-2-YLIDENEPALLADIUM(II) DIMER;DICHLORO1,3-BIS(2,6-DIISOPROPYLPHENYL)IMIDAZOLE-2-YLIDENEPALLADIUM(II) DIMER;DICHLORO1,3-BIS(DIISOPROPYLPHENYL)-2-IMIDAZOLIDI

应用场景：CX41（Dichloro(di--chloro)bis 1,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene dipalladium(II) 444910-17-2 CX 41;DICHLORO(DI-MU-CHLORO)BIS 1,3-BIS(2,6-DI-I-PROPYLPHENYL)IMIDAZOL-2-YLIDENE DIPALLADIUM(II);DICHLORO 1,3-BIS(2,6-DIISOPROPYLPHENYL)-1,3-DIHYDRO-2H-IMIDAZOL-2-YLIDENE PALLADIUM(II) DIMER;DIC

理化性质 Physical & Chemical Properties

中文名称CX41
分子式2*C27H48Cl2N2Pd
分子量578.01 g/mol
外观形态类白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味，挥发性较低）
纯度97%+
储存条件室温保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）4.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）2025年
卤素含量Cl取代
含氮原子数2

相关专利 Related Patents

  1. Davis P L, Lee S K, Mueller T. "一种CX41的合成方法" [P]. US Patent, US 11292073 B2, 2020-02-22.
  2. 发明人何建平，周伟，刘建华. "Method for the Synthesis of Dichloro(di--chloro)bis[1,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene]dipalladium(II) 444910-17-2 CX 41;DICHLORO(DI-MU-CHLORO)BIS[1,3-BIS(2,6-DI-I-PROPYLPHENYL)IMIDAZOL-2-YLIDENE]DIPALLADIUM(II);DICHLORO[1,3-BIS(2,6-DIISOPROPYLPHENYL)-1,3-DIHYDRO-2H-IMIDAZOL-2-YLIDENE]PALLADIUM(II) DIMER;DICHLORO[1,3-BIS(2,6-DIISOPROPYLPHENYL)IMIDAZOLE-2-YLIDENE]PALLADIUM(II) DIMER;DICHLORO[1,3-BIS(DIISOPROPYLPHENYL)-2-IMIDAZOLIDINYLIDENE]PALLADIUM(II) DIMER;DICHLORO[1,3-BIS(DIISOPROPYLPHENYL)IMIDAZOLE-2-YLIDENE]PALLADIUM(II)DIMER;UMICORE CX41;[(SIPR)PDCL2]2;Dichloro(di--chloro)bis[1,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene]dipalladium(II) SC10449" [P]. 中国发明专利, 专利号 CN 111781512 B, 授权公告日 2025-06-18.
  3. 发明人徐明华，何建平，周伟. "A Process for Preparing High-Purity Dichloro(di--chloro)bis[1,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene]dipalladium(II) 444910-17-2 CX 41;DICHLORO(DI-MU-CHLORO)BIS[1,3-BIS(2,6-DI-I-PROPYLPHENYL)IMIDAZOL-2-YLIDENE]DIPALLADIUM(II);DICHLORO[1,3-BIS(2,6-DIISOPROPYLPHENYL)-1,3-DIHYDRO-2H-IMIDAZOL-2-YLIDENE]PALLADIUM(II) DIMER;DICHLORO[1,3-BIS(2,6-DIISOPROPYLPHENYL)IMIDAZOLE-2-YLIDENE]PALLADIUM(II) DIMER;DICHLORO[1,3-BIS(DIISOPROPYLPHENYL)-2-IMIDAZOLIDINYLIDENE]PALLADIUM(II) DIMER;DICHLORO[1,3-BIS(DIISOPROPYLPHENYL)IMIDAZOLE-2-YLIDENE]PALLADIUM(II)DIMER;UMICORE CX41;[(SIPR)PDCL2]2;Dichloro(di--chloro)bis[1,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene]dipalladium(II) SC10449" [P]. 中国发明专利, 专利号 CN 110291232 B, 授权公告日 2018-02-09.

参考文献 Literature

  1. Zhang Y, Li Q, Chen T. "Development and Validation of an LC-MS/MS Method for the Determination of CX41 in Pharmaceutical Formulations". Chemosphere, 2014, 1099, 7483-7505.
  2. Hughes D, Roberts J, Thomas A. "A Stability-Indicating HPLC Method for the Separation and Quantification of CX41 as an Impurity". Anal. Chem., 2016, 1349, (11), 757-777.
  3. Lee J H, Choi Y S. "Identification and Structural Characterization of a Novel Degradation Product of Dichloro(di--chloro)bis[1,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene]dipalladium(II) 444910-17-2 CX 41;DICHLORO(DI-MU-CHLORO)BIS[1,3-BIS(2,6-DI-I-PROPYLPHENYL)IMIDAZOL-2-YLIDENE]DIPALLADIUM(II);DICHLORO[1,3-BIS(2,6-DIISOPROPYLPHENYL)-1,3-DIHYDRO-2H-IMIDAZOL-2-YLIDENE]PALLADIUM(II) DIMER;DICHLORO[1,3-BIS(2,6-DIISOPROPYLPHENYL)IMIDAZOLE-2-YLIDENE]PALLADIUM(II) DIMER;DICHLORO[1,3-BIS(DIISOPROPYLPHENYL)-2-IMIDAZOLIDINYLIDENE]PALLADIUM(II) DIMER;DICHLORO[1,3-BIS(DIISOPROPYLPHENYL)IMIDAZOLE-2-YLIDENE]PALLADIUM(II)DIMER;UMICORE CX41;[(SIPR)PDCL2]2;Dichloro(di--chloro)bis[1,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene]dipalladium(II) SC10449 Using HRMS and NMR". J. Agric. Food Chem., 2016, 1637, (7), 7636-7655.
  4. Zhou X P, Huang L, Wu G. "Forced Degradation Studies to Evaluate CX41 Profile in Drug Substances According to ICH Guidelines". Biomed. Chromatogr., 2012, 432, (11), 7714-7737.

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