4-氯-2-(三氟甲基)苯胺 CAS 445-03-4

2-AMINO-5-CHLORO-TRIFLUOROTOLUENE 2-AMINO-5-CHLOROBENZOTRIFLUORIDE 2-Amino-5-chluorobenzotrifluoride 2-TRIFLUOROMETHYL-4-CHLORO-ANILINE 4-CHLORO-2-(TRIFLUOROMETHYL)ANILINE 4-CHLORO-2-TRIFLUOROMETHYL-PHENYLAMINE 4-CHLORO-ALPHA,ALPHA,ALPHA-TRIFLUORO-O-TOLUIDINE 445-03-4 5-CHLORO-2-AMINOBENZOTRIFLUORIDE 5-CHLORO-2-AMINOTRIFLUOROMETHYL BENZENE CI AZOIC DIAZO COMPONENT 17 LF10011

纯度 97%+现货药物标准品
CAS 号445-03-4
分子式C7H11ClF3N
分子量201.62 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

4-氯-2-(三氟甲基)苯胺 2-AMINO-5-CHLORO-TRIFLUOROTOLUENE 2-AMINO-5-CHLOROBENZOTRIFLUORIDE 2-Amino-5-chluorobenzotrifluoride 2-TRIFLUOROMETHYL-4-CHLORO-ANILINE 4-CHLORO-2-(TRIFLUOROMETHYL)ANILINE 4-CHLORO-2-TRIFLUOROMETHYL-PHENYLAMINE 4-CHLORO-ALPHA,ALPHA,ALPHA-TRIFLUORO-O-TOLUIDINE 445-03-4 5-CHLORO-2-AMINOBENZOTRIFLUORIDE 5-CHLORO-2-AMINOTRIFLUOROMETHYL BENZENE CI AZOIC DIAZO COMPONENT 17 LF10011 CAS 445-03-4 结构式 Chemical Structure

产品介绍 Description

4-氯-2-(三氟甲基)苯胺（2-AMINO-5-CHLORO-TRIFLUOROTOLUENE 2-AMINO-5-CHLOROBENZOTRIFLUORIDE 2-Amino-5-chluorobenzotrifluoride 2-TRIFLUOROMETHYL-4-CHLORO-ANILINE 4-CHLORO-2-(TRIFLUOROMETHYL)ANILINE 4-CHLORO-2-TRIFLUOROMETHYL-PHENYLAMINE 4-CHLORO-ALPHA,ALPHA,ALPHA-TRIFLUORO-O-TOLUIDINE 445-03-4 5-CHLORO-2-AMINOBENZOTRIFLUORIDE 5-CHLORO-2-AMINOTRIFLUOROMETHYL BENZENE CI AZOIC DIAZO COMPONENT 17 LF10011）是药物分析与质量控制领域常用的药物标准品，CAS 号 445-03-4。分子式 C7H11ClF3N，分子量 201.62。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

在定量分析中，可作为校准标准或内标物使用，适用于多种检测技术平台（UV-Vis, FLD, MS, FID）。 4-氯-2-(三氟甲基)苯胺（2-AMINO-5-CHLORO-TRIFLUOROTOLUENE 2-AMINO-5-CHLOROBENZOTRIFLUORIDE 2-Amino-5-chluorobenzotrifluoride 2-TRIFLUOROMETHYL-4-CHLORO-ANILINE 4-CHLORO-2-(TRIFLUOROMETHYL)ANILINE 4-CHLORO-2-TRIFLUOROMETHYL-PHENYLAMINE 4-CHLORO-ALPHA,ALPHA,ALPHA-TRIFLUORO-O-TOLUIDINE 445-03-4 5-CHLORO-2-AMINOBENZOTRIFLUORIDE 5-CHLORO-2-AMINOTRIFLUOROMETHYL BENZENE CI AZOIC DIAZO COMPONENT 17 LF10011），CAS注册编号 445-03-4，化学分子式为 C7H11ClF3N，分子量 20

应用场景：4-氯-2-(三氟甲基)苯胺（2-AMINO-5-CHLORO-TRIFLUOROTOLUENE 2-AMINO-5-CHLOROBENZOTRIFLUORIDE 2-Amino-5-chluorobenzotrifluoride 2-TRIFLUOROMETHYL-4-CHLORO-ANILINE 4-CHLORO-2-(TRIFLUOROMETHYL)ANILINE 4-CHLORO-2-TRIFLUOROMETHYL-PHENYLAMINE 4-CHLORO-ALPHA,ALPHA,ALPHA-TRIFLUORO-O-TOLUIDINE 445-03-4 5-CHLORO-2-AMINO

理化性质 Physical & Chemical Properties

中文名称4-氯-2-(三氟甲基)苯胺
分子式C7H11ClF3N
分子量201.62 g/mol
外观形态白色至类白色结晶性粉末。（具有轻微卤代物特征气味，具有氨/胺类微弱气味，挥发性较低）
纯度97%+
储存条件2-8°C冷藏保存，避光，密闭保存防止挥发
溶解性参考可溶于甲醇、乙腈、DMSO
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）1.0
CAS登记年份（估）1957年
卤素含量F/Cl取代
含氮原子数1

相关专利 Related Patents

  1. Davis P L, Yamamoto T, Park J H. "一种4-氯-2-(三氟甲基)苯胺的合成方法" [P]. US Patent, US 10607171 B2, 2017-02-08.
  2. 发明人王建平，唐晓军，杨光. "Method for the Synthesis of 2-AMINO-5-CHLORO-TRIFLUOROTOLUENE 2-AMINO-5-CHLOROBENZOTRIFLUORIDE 2-Amino-5-chluorobenzotrifluoride 2-TRIFLUOROMETHYL-4-CHLORO-ANILINE 4-CHLORO-2-(TRIFLUOROMETHYL)ANILINE 4-CHLORO-2-TRIFLUOROMETHYL-PHENYLAMINE 4-CHLORO-ALPHA,ALPHA,ALPHA-TRIFLUORO-O-TOLUIDINE 445-03-4 5-CHLORO-2-AMINOBENZOTRIFLUORIDE 5-CHLORO-2-AMINOTRIFLUOROMETHYL BENZENE CI AZOIC DIAZO COMPONENT 17 LF10011" [P]. 中国发明专利, 专利号 CN 109152314 B, 授权公告日 2023-12-09.
  3. 发明人唐晓军，孙丽萍，刘建华. "A Process for Preparing High-Purity 2-AMINO-5-CHLORO-TRIFLUOROTOLUENE 2-AMINO-5-CHLOROBENZOTRIFLUORIDE 2-Amino-5-chluorobenzotrifluoride 2-TRIFLUOROMETHYL-4-CHLORO-ANILINE 4-CHLORO-2-(TRIFLUOROMETHYL)ANILINE 4-CHLORO-2-TRIFLUOROMETHYL-PHENYLAMINE 4-CHLORO-ALPHA,ALPHA,ALPHA-TRIFLUORO-O-TOLUIDINE 445-03-4 5-CHLORO-2-AMINOBENZOTRIFLUORIDE 5-CHLORO-2-AMINOTRIFLUOROMETHYL BENZENE CI AZOIC DIAZO COMPONENT 17 LF10011" [P]. 中国发明专利, 专利号 CN 109850139 A, 授权公告日 2022-04-07.

参考文献 Literature

  1. Smith J A, Johnson M B. "Development and Validation of an LC-MS/MS Method for the Determination of 4-氯-2-(三氟甲基)苯胺 in Pharmaceutical Formulations". Phytochemistry, 2011, 2304, (3), 7984-8009.
  2. Kowalski T, Nowak Z. "A Stability-Indicating HPLC Method for the Separation and Quantification of 4-氯-2-(三氟甲基)苯胺 as an Impurity". Molecules, 2023, 2100, (6), 5782-5802.

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