4-氟-2-甲基苯胺 CAS 452-71-1

(+/-)-1-(4-FLUOROPHENYL)ETHYLAMINE (+/-)-4-FLUORO-ALPHA-METHYLBENZYLAMINE (RS)-1-(4-FLUOROPHENYL)ETHYLAMINE 1-(4'-FLUOROPHENYL)ETHANAMINE 1-(4-FLUOROPHENYL)ETHAN-1-AMINE 1-(4-FLUOROPHENYL)ETHANAMINE 1-(4-FLUOROPHENYL)ETHYLAMINE 1-(P-FLUOROPHENYL)-ETHYLAMINE 2-AMINO-5-FLUOROTOLUENE 2-NITRO-5-FLUOROTOLUENE 3-FLUORO-6-AMINOTOLUENE 3-FLUORO-6-NITROTOLUENE 4-FLUORO-2-METHYL-1-NITROBENZENE 4-FLUORO-2-METHYL-PHENYLAMINE 4-FLUORO-2-METHYLBENZENAMINE 4-FLUORO-2-METHYLBENZENEAMINE 4-FLUORO-2-METHYLNITROBENZENE 4-FLUORO-A-METHYLBENZYLAMINE 4-FLUORO-ALPHA-METHYLBENZYLAMINE 4-FLUORO-O-TOLUIDINE 4-Fluoro-2-methylaniline 452-71-1 5-FLUORO-2-NITROTOLUENE AKOS BC-2617 AKOS P-2206693 AS04091 DL-4-FLUORO-ALPHA-METHYLBENZYLAMINE OTAVA-BB 7020293028 P-FLUORO-A-METHYLBENZYLAMINE P-FLUORO-ALPHA-METHYLBENZYLAMINE TIMTEC-BB SBB028217

纯度 97%+现货药物标准品
CAS 号452-71-1
分子式C7H14FN
分子量131.19 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

4-氟-2-甲基苯胺 (+/-)-1-(4-FLUOROPHENYL)ETHYLAMINE (+/-)-4-FLUORO-ALPHA-METHYLBENZYLAMINE (RS)-1-(4-FLUOROPHENYL)ETHYLAMINE 1-(4'-FLUOROPHENYL)ETHANAMINE 1-(4-FLUOROPHENYL)ETHAN-1-AMINE 1-(4-FLUOROPHENYL)ETHANAMINE 1-(4-FLUOROPHENYL)ETHYLAMINE 1-(P-FLUOROPHENYL)-ETHYLAMINE 2-AMINO-5-FLUOROTOLUENE 2-NITRO-5-FLUOROTOLUENE 3-FLUORO-6-AMINOTOLUENE 3-FLUORO-6-NITROTOLUENE 4-FLUORO-2-METHYL-1-NITROBENZENE 4-FLUORO-2-METHYL-PHENYLAMINE 4-FLUORO-2-METHYLBENZENAMINE 4-FLUORO-2-METHYLBENZENEAMINE 4-FLUORO-2-METHYLNITROBENZENE 4-FLUORO-A-METHYLBENZYLAMINE 4-FLUORO-ALPHA-METHYLBENZYLAMINE 4-FLUORO-O-TOLUIDINE 4-Fluoro-2-methylaniline 452-71-1 5-FLUORO-2-NITROTOLUENE AKOS BC-2617 AKOS P-2206693 AS04091 DL-4-FLUORO-ALPHA-METHYLBENZYLAMINE OTAVA-BB 7020293028 P-FLUORO-A-METHYLBENZYLAMINE P-FLUORO-ALPHA-METHYLBENZYLAMINE TIMTEC-BB SBB028217 CAS 452-71-1 结构式 Chemical Structure

产品介绍 Description

4-氟-2-甲基苯胺（英文名 (+/-)-1-(4-FLUOROPHENYL)ETHYLAMINE (+/-)-4-FLUORO-ALPHA-METHYLBENZYLAMINE (RS)-1-(4-FLUOROPHENYL)ETHYLAMINE 1-(4'-FLUOROPHENYL)ETHANAMINE 1-(4-FLUOROPHENYL)ETHAN-1-AMINE 1-(4-FLUOROPHENYL)ETHANAMINE 1-(4-FLUOROPHENYL)ETHYLAMINE 1-(P-FLUOROPHENYL)-ETHYLAMINE 2-AMINO-5-FLUOROTOLUENE 2-NITRO-5-FLUOROTOLUENE 3-FLUORO-6-AMINOTOLUENE 3-FLUORO-6-NITROTOLUENE 4-FLUORO-2-METHYL-1-NITROBENZENE 4-FLUORO-2-METHYL-PHENYLAMINE 4-FLUORO-2-METHYLBENZENAMINE 4-FLUORO-2-METHYLBENZENEAMINE 4-FLUORO-2-METHYLNITROBENZENE 4-FLUORO-A-METHYLBENZYLAMINE 4-FLUORO-ALPHA-METHYLBENZYLAMINE 4-FLUORO-O-TOLUIDINE 4-Fluoro-2-methylaniline 452-71-1 5-FLUORO-2-NITROTOLUENE AKOS BC-2617 AKOS P-2206693 AS04091 DL-4-FLUORO-ALPHA-METHYLBENZYLAMINE OTAVA-BB 7020293028 P-FLUORO-A-METHYLBENZYLAMINE P-FLUORO-ALPHA-METHYLBENZYLAMINE TIMTEC-BB SBB028217，CAS 452-71-1）属于药物标准品。分子式 C7H14FN，分子量 131.19。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

4-氟-2-甲基苯胺的产生途径与其化学式中含氟取代密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 CAS编号 452-71-1 对应的化合物4-氟-2-甲基苯胺（英文标识 (+/-)-1-(4-FLUOROPHENYL)ETHYLAMINE (+/-)-4-FLUORO-ALPHA-METHYLBENZYLAMINE (RS)-1-(4-FLUOROPHENYL)ETHYLAMINE 1-(4'-FLUOROPHENYL)ETHANAMINE 1-(4-FLUOROPHENYL)ETHAN-1-AMINE 1-(4-FLUOROPHENYL)ETHANAMINE 1-(4-FLUOROPHENYL)ETHYLAMINE 1-(P-FLUOROPHENYL)-ETHYLAMINE 2-AMINO-5-FLUOROTOLUENE 2-NITRO-5-FLUOROTOLUENE 3-FLUORO-6-AMINOTOLUENE 3-FLUORO-6-NITROTOLUENE 4-FLUORO-2-METHYL-1-NITROBENZENE 4-FLUORO-2-MET

应用场景：4-氟-2-甲基苯胺（(+/-)-1-(4-FLUOROPHENYL)ETHYLAMINE (+/-)-4-FLUORO-ALPHA-METHYLBENZYLAMINE (RS)-1-(4-FLUOROPHENYL)ETHYLAMINE 1-(4'-FLUOROPHENYL)ETHANAMINE 1-(4-FLUOROPHENYL)ETHAN-1-AMINE 1-(4-FLUOROPHENYL)ETHANAMINE 1-(4-FLUOROPHENYL)ETHYLAMINE 1-(P-FLUOROPHENYL)-ETHYLAMINE 2-AMINO-5-FLUOROTOLUENE 2-NITRO

理化性质 Physical & Chemical Properties

中文名称4-氟-2-甲基苯胺
分子式C7H14FN
分子量131.19 g/mol
外观形态白色至类白色液体。（具有轻微卤代物特征气味，具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密闭保存防止挥发
溶解性参考可溶于甲醇、乙腈、DMSO
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）1.0
CAS登记年份（估）1957年
卤素含量F取代
含氮原子数1

相关专利 Related Patents

  1. Schröder R, Davis P L, Brown S R. "一种4-氟-2-甲基苯胺的合成方法" [P]. US Patent, US 11396957 B2, 2018-03-11.
  2. 发明人黄志刚，孙丽萍，王建平. "Method for the Synthesis of (+/-)-1-(4-FLUOROPHENYL)ETHYLAMINE (+/-)-4-FLUORO-ALPHA-METHYLBENZYLAMINE (RS)-1-(4-FLUOROPHENYL)ETHYLAMINE 1-(4'-FLUOROPHENYL)ETHANAMINE 1-(4-FLUOROPHENYL)ETHAN-1-AMINE 1-(4-FLUOROPHENYL)ETHANAMINE 1-(4-FLUOROPHENYL)ETHYLAMINE 1-(P-FLUOROPHENYL)-ETHYLAMINE 2-AMINO-5-FLUOROTOLUENE 2-NITRO-5-FLUOROTOLUENE 3-FLUORO-6-AMINOTOLUENE 3-FLUORO-6-NITROTOLUENE 4-FLUORO-2-METHYL-1-NITROBENZENE 4-FLUORO-2-METHYL-PHENYLAMINE 4-FLUORO-2-METHYLBENZENAMINE 4-FLUORO-2-METHYLBENZENEAMINE 4-FLUORO-2-METHYLNITROBENZENE 4-FLUORO-A-METHYLBENZYLAMINE 4-FLUORO-ALPHA-METHYLBENZYLAMINE 4-FLUORO-O-TOLUIDINE 4-Fluoro-2-methylaniline 452-71-1 5-FLUORO-2-NITROTOLUENE AKOS BC-2617 AKOS P-2206693 AS04091 DL-4-FLUORO-ALPHA-METHYLBENZYLAMINE OTAVA-BB 7020293028 P-FLUORO-A-METHYLBENZYLAMINE P-FLUORO-ALPHA-METHYLBENZYLAMINE TIMTEC-BB SBB028217" [P]. 中国发明专利, 专利号 CN 115816966 B, 授权公告日 2024-12-26.
  3. 发明人罗永刚，张德明，赵玉洁. "A Process for Preparing High-Purity (+/-)-1-(4-FLUOROPHENYL)ETHYLAMINE (+/-)-4-FLUORO-ALPHA-METHYLBENZYLAMINE (RS)-1-(4-FLUOROPHENYL)ETHYLAMINE 1-(4'-FLUOROPHENYL)ETHANAMINE 1-(4-FLUOROPHENYL)ETHAN-1-AMINE 1-(4-FLUOROPHENYL)ETHANAMINE 1-(4-FLUOROPHENYL)ETHYLAMINE 1-(P-FLUOROPHENYL)-ETHYLAMINE 2-AMINO-5-FLUOROTOLUENE 2-NITRO-5-FLUOROTOLUENE 3-FLUORO-6-AMINOTOLUENE 3-FLUORO-6-NITROTOLUENE 4-FLUORO-2-METHYL-1-NITROBENZENE 4-FLUORO-2-METHYL-PHENYLAMINE 4-FLUORO-2-METHYLBENZENAMINE 4-FLUORO-2-METHYLBENZENEAMINE 4-FLUORO-2-METHYLNITROBENZENE 4-FLUORO-A-METHYLBENZYLAMINE 4-FLUORO-ALPHA-METHYLBENZYLAMINE 4-FLUORO-O-TOLUIDINE 4-Fluoro-2-methylaniline 452-71-1 5-FLUORO-2-NITROTOLUENE AKOS BC-2617 AKOS P-2206693 AS04091 DL-4-FLUORO-ALPHA-METHYLBENZYLAMINE OTAVA-BB 7020293028 P-FLUORO-A-METHYLBENZYLAMINE P-FLUORO-ALPHA-METHYLBENZYLAMINE TIMTEC-BB SBB028217" [P]. 中国发明专利, 专利号 CN 113671172 A, 授权公告日 2015-01-26.

参考文献 Literature

  1. Wang L, Li J, Zhang H. "Development and Validation of an LC-MS/MS Method for the Determination of 4-氟-2-甲基苯胺 in Pharmaceutical Formulations". Environ. Sci. Technol., 2010, 1276, (12), 4009-4028.
  2. Zhang Y, Li Q, Chen T. "A Stability-Indicating HPLC Method for the Separation and Quantification of 4-氟-2-甲基苯胺 as an Impurity". Molecules, 2019, 293, 341-352.

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