4-氟苯甲酰肼 CAS 456-06-4

4-FLUORO BENZOYL HYDRAZINE 4-FLUOROBENZENECARBOHYDRAZIDE 4-FLUOROBENZHYDRAZIDE 4-FLUOROBENZOHYDRAZIDE 4-FLUOROBENZOHYDRAZIDE HYDRATE 4-FLUOROBENZOIC ACID HYDRAZIDE 4-FLUOROBENZOIC HYDRAZIDE HYDRATE 4-Fluorobenzoic hydrazide 456-06-4 AKOS B020279 AKOS BBR-002483 AKOS BBS-00004506 ART-CHEM-BB ACB002930 ART-CHEM-BB B020279 AS00306 ASISCHEM R36621 BUTTPARK 35\03-73 OTAVA-BB 7119846924 TIMTEC-BB SBB002375

纯度 97%+现货药物标准品
CAS 号456-06-4
分子式C7H13FN2O
分子量160.19 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

4-氟苯甲酰肼 4-FLUORO BENZOYL HYDRAZINE 4-FLUOROBENZENECARBOHYDRAZIDE 4-FLUOROBENZHYDRAZIDE 4-FLUOROBENZOHYDRAZIDE 4-FLUOROBENZOHYDRAZIDE HYDRATE 4-FLUOROBENZOIC ACID HYDRAZIDE 4-FLUOROBENZOIC HYDRAZIDE HYDRATE 4-Fluorobenzoic hydrazide 456-06-4 AKOS B020279 AKOS BBR-002483 AKOS BBS-00004506 ART-CHEM-BB ACB002930 ART-CHEM-BB B020279 AS00306 ASISCHEM R36621 BUTTPARK 35\03-73 OTAVA-BB 7119846924 TIMTEC-BB SBB002375 CAS 456-06-4 结构式 Chemical Structure

产品介绍 Description

4-氟苯甲酰肼（英文名 4-FLUORO BENZOYL HYDRAZINE 4-FLUOROBENZENECARBOHYDRAZIDE 4-FLUOROBENZHYDRAZIDE 4-FLUOROBENZOHYDRAZIDE 4-FLUOROBENZOHYDRAZIDE HYDRATE 4-FLUOROBENZOIC ACID HYDRAZIDE 4-FLUOROBENZOIC HYDRAZIDE HYDRATE 4-Fluorobenzoic hydrazide 456-06-4 AKOS B020279 AKOS BBR-002483 AKOS BBS-00004506 ART-CHEM-BB ACB002930 ART-CHEM-BB B020279 AS00306 ASISCHEM R36621 BUTTPARK 35\03-73 OTAVA-BB 7119846924 TIMTEC-BB SBB002375，CAS 456-06-4）属于药物标准品。分子式 C7H13FN2O，分子量 160.19。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

与同类药物标准品相比，4-氟苯甲酰肼的分子量为160.19 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 4-氟苯甲酰肼（4-FLUORO BENZOYL HYDRAZINE 4-FLUOROBENZENECARBOHYDRAZIDE 4-FLUOROBENZHYDRAZIDE 4-FLUOROBENZOHYDRAZIDE 4-FLUOROBENZOHYDRAZIDE HYDRATE 4-FLUOROBENZOIC ACID HYDRAZIDE 4-FLUOROBENZOIC HYDRAZIDE HYDRATE 4-Fluorobenzoic hydrazide 456-06-4 AKOS B020279 AKOS BBR-002483 AKOS BBS-00004506 ART-CHEM-BB ACB002930 ART-CHEM-BB B020279 AS00306 ASISCHEM R36621 BUTTPARK 35\03-73 OTAVA-BB 7119846924 TIMTEC-BB SBB002375），CAS注册编号 456-06-4，化学分子

应用场景：针对化学分析用途，4-氟苯甲酰肼（4-FLUORO BENZOYL HYDRAZINE 4-FLUOROBENZENECARBOHYDRAZIDE 4-FLUOROBENZHYDRAZIDE 4-FLUOROBENZOHYDRAZIDE 4-FLUOROBENZOHYDRAZIDE HYDRATE 4-FLUOROBENZOIC ACID HYDRAZIDE 4-FLUOROBENZOIC HYDRAZIDE HYDRATE 4-Fluorobenzoic hydrazide 456-06-4 AKOS B020279 AKOS BBR-002483 AKOS BBS-00004506 ART

理化性质 Physical & Chemical Properties

中文名称4-氟苯甲酰肼
分子式C7H13FN2O
分子量160.19 g/mol
外观形态白色至类白色结晶性粉末。（具有轻微卤代物特征气味，具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密闭保存防止挥发
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.0
CAS登记年份（估）1957年
卤素含量F取代
含氮原子数2

相关专利 Related Patents

  1. 发明人陈志强，何建平，周伟. "一种4-氟苯甲酰肼的合成方法" [P]. 中国发明专利, 专利号 CN 117154865 A, 授权公告日 2022-03-10.
  2. 发明人林芳，朱建伟，周伟. "Method for the Synthesis of 4-FLUORO BENZOYL HYDRAZINE 4-FLUOROBENZENECARBOHYDRAZIDE 4-FLUOROBENZHYDRAZIDE 4-FLUOROBENZOHYDRAZIDE 4-FLUOROBENZOHYDRAZIDE HYDRATE 4-FLUOROBENZOIC ACID HYDRAZIDE 4-FLUOROBENZOIC HYDRAZIDE HYDRATE 4-Fluorobenzoic hydrazide 456-06-4 AKOS B020279 AKOS BBR-002483 AKOS BBS-00004506 ART-CHEM-BB ACB002930 ART-CHEM-BB B020279 AS00306 ASISCHEM R36621 BUTTPARK 35\03-73 OTAVA-BB 7119846924 TIMTEC-BB SBB002375" [P]. 中国发明专利, 专利号 CN 116041623 B, 授权公告日 2017-12-07.

参考文献 Literature

  1. Yamamoto K, Tanaka H, Suzuki T. "Development and Validation of an LC-MS/MS Method for the Determination of 4-氟苯甲酰肼 in Pharmaceutical Formulations". Chromatographia, 2020, 230, (5), 9479-9495.
  2. Hughes D, Roberts J, Thomas A. "A Stability-Indicating HPLC Method for the Separation and Quantification of 4-氟苯甲酰肼 as an Impurity". Rapid Commun. Mass Spectrom., 2015, 1576, 6270-6293.
  3. Fischer P, Wagner E. "Identification and Structural Characterization of a Novel Degradation Product of 4-FLUORO BENZOYL HYDRAZINE 4-FLUOROBENZENECARBOHYDRAZIDE 4-FLUOROBENZHYDRAZIDE 4-FLUOROBENZOHYDRAZIDE 4-FLUOROBENZOHYDRAZIDE HYDRATE 4-FLUOROBENZOIC ACID HYDRAZIDE 4-FLUOROBENZOIC HYDRAZIDE HYDRATE 4-Fluorobenzoic hydrazide 456-06-4 AKOS B020279 AKOS BBR-002483 AKOS BBS-00004506 ART-CHEM-BB ACB002930 ART-CHEM-BB B020279 AS00306 ASISCHEM R36621 BUTTPARK 35\03-73 OTAVA-BB 7119846924 TIMTEC-BB SBB002375 Using HRMS and NMR". Talanta, 2022, 2428, (12), 2585-2605.
  4. Fischer P, Wagner E. "Forced Degradation Studies to Evaluate 4-氟苯甲酰肼 Profile in Drug Substances According to ICH Guidelines". J. Pharm. Biomed. Anal., 2013, 2170, (5), 4884-4898.

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