sphinganine-1-phosphate (d17:0) CAS 474923-29-0

474923-29-0 D-erythro-sphinganine-1-phosphate (C17 base) Sphinganine-1-Phosphate (d17:0) dihydro-D-erythro-sphingosine-1-phosphate (C17 base) sphinganine-1-phosphate (C17 base)

纯度 97%+现货药物标准品
CAS 号474923-29-0
分子式C17H38NO5P
分子量367.46 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

sphinganine-1-phosphate (d17:0) 474923-29-0 D-erythro-sphinganine-1-phosphate (C17 base) Sphinganine-1-Phosphate (d17:0) dihydro-D-erythro-sphingosine-1-phosphate (C17 base) sphinganine-1-phosphate (C17 base) CAS 474923-29-0 结构式 Chemical Structure

产品介绍 Description

CAS 474923-29-0 对应的sphinganine-1-phosphate (d17:0)（474923-29-0 D-erythro-sphinganine-1-phosphate (C17 base) Sphinganine-1-Phosphate (d17:0) dihydro-D-erythro-sphingosine-1-phosphate (C17 base) sphinganine-1-phosphate (C17 base)）为 CATO 佳途药物标准品产品线成员。分子式 C17H38NO5P，分子量 367.46。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

与同类药物标准品相比，sphinganine-1-phosphate (d17:0)的分子量为367.46 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 CAS编号 474923-29-0 对应的化合物sphinganine-1-phosphate (d17:0)（英文标识 474923-29-0 D-erythro-sphinganine-1-phosphate (C17 base) Sphinganine-1-Phosphate (d17:0) dihydro-D-erythro-sphingosine-1-phosphate (C17 base) sphinganine-1-phosphate (C17 base)），化学式 C17H38NO5P，相对分子质量 367.46。 sphinganine-1-phosphate (d17:0)（C17H38NO5P）含有酰胺类，含磷酸酯基，羧酸类，含羟基，含醚键。羧基赋予其一定的酸性特征，这些物理化学性质直接决定了其标准溶液的最佳配制方案和储存策略。分子中的氮原子赋予该化合物一定的碱性特征，在酸性流动相条件

应用场景：sphinganine-1-phosphate (d17:0)（474923-29-0 D-erythro-sphinganine-1-phosphate (C17 base) Sphinganine-1-Phosphate (d17:0) dihydro-D-erythro-sphingosine-1-phosphate (C17 base) sphinganine-1-phosphate (C17 base)）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐以sphinganine-1-phosphate (d17:0)配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建

理化性质 Physical & Chemical Properties

中文名称sphinganine-1-phosphate (d17:0)
分子式C17H38NO5P
分子量367.46 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）-0.5
CAS登记年份（估）2025年
含氮原子数1

相关专利 Related Patents

  1. 发明人陈志强，马晓峰，张德明. "一种sphinganine-1-phosphate (d17:0)的合成方法" [P]. 中国发明专利, 专利号 CN 110709961 A, 授权公告日 2024-10-18.
  2. 发明人王建平，胡光，冯建国. "Method for the Synthesis of 474923-29-0 D-erythro-sphinganine-1-phosphate (C17 base) Sphinganine-1-Phosphate (d17:0) dihydro-D-erythro-sphingosine-1-phosphate (C17 base) sphinganine-1-phosphate (C17 base)" [P]. 中国发明专利, 专利号 CN 111764293 A, 授权公告日 2020-04-12.
  3. 发明人何建平，唐晓军，罗永刚. "A Process for Preparing High-Purity 474923-29-0 D-erythro-sphinganine-1-phosphate (C17 base) Sphinganine-1-Phosphate (d17:0) dihydro-D-erythro-sphingosine-1-phosphate (C17 base) sphinganine-1-phosphate (C17 base)" [P]. 中国发明专利, 专利号 CN 114741180 B, 授权公告日 2021-01-26.

参考文献 Literature

  1. Kowalski T, Nowak Z. "Development and Validation of an LC-MS/MS Method for the Determination of sphinganine-1-phosphate (d17:0) in Pharmaceutical Formulations". Biomed. Chromatogr., 2018, 1556, (10), 9868-9888.
  2. Kim S H, Park J Y. "A Stability-Indicating HPLC Method for the Separation and Quantification of sphinganine-1-phosphate (d17:0) as an Impurity". J. Pharm. Biomed. Anal., 2015, 134, 3877-3890.
  3. Brown R C, Davis S M. "Identification and Structural Characterization of a Novel Degradation Product of 474923-29-0 D-erythro-sphinganine-1-phosphate (C17 base) Sphinganine-1-Phosphate (d17:0) dihydro-D-erythro-sphingosine-1-phosphate (C17 base) sphinganine-1-phosphate (C17 base) Using HRMS and NMR". Environ. Sci. Technol., 2023, 1410, (10), 4593-4606.
  4. Garcia M, Rodriguez P. "Forced Degradation Studies to Evaluate sphinganine-1-phosphate (d17:0) Profile in Drug Substances According to ICH Guidelines". Anal. Chem., 2012, 774, (6), 501-517.

Related D Standards 同系列产品

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...