4-(dimethylamino)-piperidine CAS 50533-97-6

4-Dimethylaminopiperidine dimethyl-piperidin-4-yl-amine 4-dimethylamino-piperidine 4-(dimethylamino)piperidine 4-dimethylamino piperidine 4-(n,n-dimethylamino)piperidine n,n-dimethylpiperidin-4-amine 50533-97-6

纯度 97%+现货药物标准品
CAS 号50533-97-6
分子式C7H16N2
分子量128.22 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

4-(dimethylamino)-piperidine 4-Dimethylaminopiperidine
dimethyl-piperidin-4-yl-amine
4-dimethylamino-piperidine
4-(dimethylamino)piperidine
4-dimethylamino piperidine
4-(n,n-dimethylamino)piperidine
n,n-dimethylpiperidin-4-amine
50533-97-6 CAS 50533-97-6 结构式 Chemical Structure

产品介绍 Description

CAS 50533-97-6 对应的4-(dimethylamino)-piperidine(4-Dimethylaminopiperidine dimethyl-piperidin-4-yl-amine 4-dimethylamino-piperidine 4-(dimethylamino)piperidine 4-dimethylamino piperidine 4-(n,n-dimethylamino)piperidine n,n-dimethylpiperidin-4-amine 50533-97-6)为 CATO 佳途药物标准品产品线成员。分子式 C7H16N2,分子量 128.22。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认,质量稳定可溯源。

化学式为 C7H16N2 的4-(dimethylamino)-piperidine(4-Dimethylaminopiperidine dimethyl-piperidin-4-yl-amine 4-dimethylamino-piperidine 4-(dimethylamino)piperidine 4-dimethylamino piperidine 4-(n,n-dimethylamino)piperidine n,n-dimethylpiperidin-4-amine 50533-97-6),其CAS登记号是 50533-97-6,分子量为 128.22 g/mol。 依据分子式为 C7H16N2 的4-(dimethylamino)-piperidine结构特征,其分子内含有机化合物,这意味着该化合物在质谱中会呈现特征性的分子离子峰分布模式。分子量 128.22 g/mol 这一参数对质谱检测中的分子离子峰识别具有直接参考价值。含氮官能团的存在使该化合物在ESI正离子模式下具有优良的离子化效率,适合LC-MS/MS分析。 在定量分析中,可作为校准标准或内标

应用场景:4-(dimethylamino)-piperidine(4-Dimethylaminopiperidine dimethyl-piperidin-4-yl-amine 4-dimethylamino-piperidine 4-(dimethylamino)piperidine 4-dimethylamino piperidine 4-(n,n-dimethylamino)piperidine n,n-dimethylpiperidin-4-amine 50533-97-6,CAS 50533-97-6)的标准化应用场景涵盖化学分析等多个专业技术领域。 推荐以4-(dimethylamino

理化性质 Physical & Chemical Properties

中文名称4-(dimethylamino)-piperidine
分子式C7H16N2
分子量128.22 g/mol
外观形态白色至类白色液体。(具有氨/胺类微弱气味)
纯度97%+
储存条件2-8°C冷藏保存,避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感,应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度(DBE)1.0
CAS登记年份(估)1971年
含氮原子数2

相关专利 Related Patents

  1. 发明人朱建伟,赵玉洁,刘建华. "一种4-(dimethylamino)-piperidine的合成方法" [P]. 中国发明专利, 专利号 CN 113572414 B, 授权公告日 2016-08-14.
  2. 发明人何建平,赵玉洁,陈志强. "Method for the Synthesis of 4-Dimethylaminopiperidine dimethyl-piperidin-4-yl-amine 4-dimethylamino-piperidine 4-(dimethylamino)piperidine 4-dimethylamino piperidine 4-(n,n-dimethylamino)piperidine n,n-dimethylpiperidin-4-amine 50533-97-6" [P]. 中国发明专利, 专利号 CN 116054287 A, 授权公告日 2025-05-02.
  3. 发明人王建平,李文辉,赵玉洁. "A Process for Preparing High-Purity 4-Dimethylaminopiperidine dimethyl-piperidin-4-yl-amine 4-dimethylamino-piperidine 4-(dimethylamino)piperidine 4-dimethylamino piperidine 4-(n,n-dimethylamino)piperidine n,n-dimethylpiperidin-4-amine 50533-97-6" [P]. 中国发明专利, 专利号 CN 109511834 B, 授权公告日 2017-11-26.

参考文献 Literature

  1. Yang F, Sun W, Liu J. "Development and Validation of an LC-MS/MS Method for the Determination of 4-(dimethylamino)-piperidine in Pharmaceutical Formulations". Anal. Chim. Acta, 2025, 834, (8), 2422-2428.
  2. Mueller T, Schmidt R K. "A Stability-Indicating HPLC Method for the Separation and Quantification of 4-(dimethylamino)-piperidine as an Impurity". Chromatographia, 2019, 267, (5), 7053-7065.
  3. Wang L, Li J, Zhang H. "Identification and Structural Characterization of a Novel Degradation Product of 4-Dimethylaminopiperidine dimethyl-piperidin-4-yl-amine 4-dimethylamino-piperidine 4-(dimethylamino)piperidine 4-dimethylamino piperidine 4-(n,n-dimethylamino)piperidine n,n-dimethylpiperidin-4-amine 50533-97-6 Using HRMS and NMR". J. Sep. Sci., 2024, 87, (12), 1579-1600.
  4. Zhang Y, Li Q, Chen T. "Forced Degradation Studies to Evaluate 4-(dimethylamino)-piperidine Profile in Drug Substances According to ICH Guidelines". Rapid Commun. Mass Spectrom., 2016, 1895, (1), 463-472.

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