1-(4-Morpholinyl)-2-propanamine CAS 50998-05-5

1-Methyl-2-morpholin-4-yl-ethylamine 1-(4-morpholinyl)-2-propanamine 1-methyl-2-morpholin-4-ylethylamine 4-(2-aminopropyl)morpholine 1-(morpholin-4-yl)propan-2-amine 1-Morpholinopropan-2-amine 2-Amino-1-morpholinopropane N-(2-Aminopropyl)morpholine [1-Methyl-2-(morpholin-4-yl)ethyl]amine a-Methyl-4-morpholineethanamine 50998-05-5

纯度 97%+现货药物标准品
CAS 号50998-05-5
分子式C7H16N2O
分子量144.21 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

1-(4-Morpholinyl)-2-propanamine 1-Methyl-2-morpholin-4-yl-ethylamine 1-(4-morpholinyl)-2-propanamine 1-methyl-2-morpholin-4-ylethylamine 4-(2-aminopropyl)morpholine 1-(morpholin-4-yl)propan-2-amine 1-Morpholinopropan-2-amine 2-Amino-1-morpholinopropane N-(2-Aminopropyl)morpholine [1-Methyl-2-(morpholin-4-yl)ethyl]amine a-Methyl-4-morpholineethanamine 50998-05-5 CAS 50998-05-5 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品1-(4-Morpholinyl)-2-propanamine（1-Methyl-2-morpholin-4-yl-ethylamine 1-(4-morpholinyl)-2-propanamine 1-methyl-2-morpholin-4-ylethylamine 4-(2-aminopropyl)morpholine 1-(morpholin-4-yl)propan-2-amine 1-Morpholinopropan-2-amine 2-Amino-1-morpholinopropane N-(2-Aminopropyl)morpholine [1-Methyl-2-(morpholin-4-yl)ethyl]amine a-Methyl-4-morpholineethanamine 50998-05-5，CAS 50998-05-5），分子式 C7H16N2O，分子量 144.21。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

本品定值报告包含以下质量控制信息： - 主成分含量：97%+； - 水分/残留溶剂：通过卡尔费休（KF）和热重分析（TGA）测定并校正； - 定值方法：HPLC-DAD面积归一化法、qNMR法、DSC法等正交验证； - 不确定度：扩展不确定度（k=2）包含测量重复性、均匀性和稳定性分量。 化学式为 C7H16N2O 的1-(4-Morpholinyl)-2-propanamine（1-Methyl-2-morpholin-4-yl-ethylamine 1-(4-morpholinyl)-2-propanamine 1-methyl-2-morpholin-4-ylethylamine 4-(2-aminopropyl)morpholine 1-(morpholin-4-yl)propan-2-amine 1-Morpholinopropan-2-amine 2-Amino-1-morpholinopropane N-(2-Aminopropyl)morpholine 1-Methyl-2-(morpholin-4-yl)ethylamine a-

应用场景：1-(4-Morpholinyl)-2-propanamine（1-Methyl-2-morpholin-4-yl-ethylamine 1-(4-morpholinyl)-2-propanamine 1-methyl-2-morpholin-4-ylethylamine 4-(2-aminopropyl)morpholine 1-(morpholin-4-yl)propan-2-amine 1-Morpholinopropan-2-amine 2-Amino-1-morpholinopropane N-(2-Aminopropyl)morpholine 1-Methyl-2-(morpho

理化性质 Physical & Chemical Properties

中文名称1-(4-Morpholinyl)-2-propanamine
分子式C7H16N2O
分子量144.21 g/mol
外观形态白色至类白色液体。（具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）1.0
CAS登记年份（估）1971年
含氮原子数2

相关专利 Related Patents

  1. 发明人李文辉，张德明，冯建国. "一种1-(4-Morpholinyl)-2-propanamine的合成方法" [P]. 中国发明专利, 专利号 CN 113285831 B, 授权公告日 2021-12-25.
  2. 发明人何建平，陈志强，高志强. "Method for the Synthesis of 1-Methyl-2-morpholin-4-yl-ethylamine 1-(4-morpholinyl)-2-propanamine 1-methyl-2-morpholin-4-ylethylamine 4-(2-aminopropyl)morpholine 1-(morpholin-4-yl)propan-2-amine 1-Morpholinopropan-2-amine 2-Amino-1-morpholinopropane N-(2-Aminopropyl)morpholine [1-Methyl-2-(morpholin-4-yl)ethyl]amine a-Methyl-4-morpholineethanamine 50998-05-5" [P]. 中国发明专利, 专利号 CN 113598775 A, 授权公告日 2019-03-14.
  3. 发明人胡光，刘建华，黄志刚. "A Process for Preparing High-Purity 1-Methyl-2-morpholin-4-yl-ethylamine 1-(4-morpholinyl)-2-propanamine 1-methyl-2-morpholin-4-ylethylamine 4-(2-aminopropyl)morpholine 1-(morpholin-4-yl)propan-2-amine 1-Morpholinopropan-2-amine 2-Amino-1-morpholinopropane N-(2-Aminopropyl)morpholine [1-Methyl-2-(morpholin-4-yl)ethyl]amine a-Methyl-4-morpholineethanamine 50998-05-5" [P]. 中国发明专利, 专利号 CN 111851749 B, 授权公告日 2021-03-27.

参考文献 Literature

  1. Chen X Y, Liu M, Zhao W Q. "Development and Validation of an LC-MS/MS Method for the Determination of 1-(4-Morpholinyl)-2-propanamine in Pharmaceutical Formulations". Molecules, 2013, 990, (4), 505-514.
  2. Mueller T, Schmidt R K. "A Stability-Indicating HPLC Method for the Separation and Quantification of 1-(4-Morpholinyl)-2-propanamine as an Impurity". Anal. Chim. Acta, 2013, 305, (10), 4759-4769.
  3. Kim S H, Park J Y. "Identification and Structural Characterization of a Novel Degradation Product of 1-Methyl-2-morpholin-4-yl-ethylamine 1-(4-morpholinyl)-2-propanamine 1-methyl-2-morpholin-4-ylethylamine 4-(2-aminopropyl)morpholine 1-(morpholin-4-yl)propan-2-amine 1-Morpholinopropan-2-amine 2-Amino-1-morpholinopropane N-(2-Aminopropyl)morpholine [1-Methyl-2-(morpholin-4-yl)ethyl]amine a-Methyl-4-morpholineethanamine 50998-05-5 Using HRMS and NMR". Food Chem., 2018, 1431, (5), 4737-4755.
  4. Kim S H, Park J Y. "Forced Degradation Studies to Evaluate 1-(4-Morpholinyl)-2-propanamine Profile in Drug Substances According to ICH Guidelines". Chromatographia, 2017, 973, (1), 4273-4284.

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