4-（二氰亚甲基）-2-甲基-6-（4-二甲氨基苯乙烯基）-4 <I> H </I>-吡喃 CAS 51325-91-8

51325-91-8 4-(Dicyanomethylene)-2-methyl-6-(4-(dimethylamino)styryl)-4H-pyran (2-(2-(4-(Dimethylamino)phenyl)ethenyl)-6-methyl-4H-pyran-4-ylidene)propanedinit rile (2-(2-(4-(Dimethylamino)phenyl)vinyl)-6-methyl-4H-pyran-4-ylidene)malononitrile Malononitrile, (2-(p-(dimethylamino)styryl)-6-methyl-4H-pyran-4-ylidene)- Propanedinitrile, 2-(2-(2-(4-(dimethylamino)phenyl)ethenyl)-6-methyl-4H-pyran-4-ylidene)- Propanedinitrile, (2-(2-(4-(dimethylamino)phenyl)ethenyl)-6-methyl-4H-pyran-4-ylidene)- CCRIS 4973 (2-(2-(4-(Dimethylamino)phenyl)ethenyl)-6-methyl-4H-pyran-4-ylidene)propanedinitrile (2-(p-(Dimethylamino)styryl)-6-methyl-4H-pyran-4-ylidene)malononitrile EINECS 257-137-6

纯度 97%+现货药物标准品
CAS 号51325-91-8
分子式C19H23N3O
分子量309.41 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

4-（二氰亚甲基）-2-甲基-6-（4-二甲氨基苯乙烯基）-4 <I> H </I>-吡喃 51325-91-8 4-(Dicyanomethylene)-2-methyl-6-(4-(dimethylamino)styryl)-4H-pyran (2-(2-(4-(Dimethylamino)phenyl)ethenyl)-6-methyl-4H-pyran-4-ylidene)propanedinit rile (2-(2-(4-(Dimethylamino)phenyl)vinyl)-6-methyl-4H-pyran-4-ylidene)malononitrile Malononitrile, (2-(p-(dimethylamino)styryl)-6-methyl-4H-pyran-4-ylidene)- Propanedinitrile, 2-(2-(2-(4-(dimethylamino)phenyl)ethenyl)-6-methyl-4H-pyran-4-ylidene)- Propanedinitrile, (2-(2-(4-(dimethylamino)phenyl)ethenyl)-6-methyl-4H-pyran-4-ylidene)- CCRIS 4973 (2-(2-(4-(Dimethylamino)phenyl)ethenyl)-6-methyl-4H-pyran-4-ylidene)propanedinitrile (2-(p-(Dimethylamino)styryl)-6-methyl-4H-pyran-4-ylidene)malononitrile EINECS 257-137-6 CAS 51325-91-8 结构式 Chemical Structure

产品介绍 Description

4-（二氰亚甲基）-2-甲基-6-（4-二甲氨基苯乙烯基）-4 <I> H </I>-吡喃（英文名 51325-91-8 4-(Dicyanomethylene)-2-methyl-6-(4-(dimethylamino)styryl)-4H-pyran (2-(2-(4-(Dimethylamino)phenyl)ethenyl)-6-methyl-4H-pyran-4-ylidene)propanedinit rile (2-(2-(4-(Dimethylamino)phenyl)vinyl)-6-methyl-4H-pyran-4-ylidene)malononitrile Malononitrile, (2-(p-(dimethylamino)styryl)-6-methyl-4H-pyran-4-ylidene)- Propanedinitrile, 2-(2-(2-(4-(dimethylamino)phenyl)ethenyl)-6-methyl-4H-pyran-4-ylidene)- Propanedinitrile, (2-(2-(4-(dimethylamino)phenyl)ethenyl)-6-methyl-4H-pyran-4-ylidene)- CCRIS 4973 (2-(2-(4-(Dimethylamino)phenyl)ethenyl)-6-methyl-4H-pyran-4-ylidene)propanedinitrile (2-(p-(Dimethylamino)styryl)-6-methyl-4H-pyran-4-ylidene)malononitrile EINECS 257-137-6，CAS 51325-91-8）属于药物标准品。分子式 C19H23N3O，分子量 309.41。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

化学式为 C19H23N3O 的4-（二氰亚甲基）-2-甲基-6-（4-二甲氨基苯乙烯基）-4 <I> H </I>-吡喃（51325-91-8 4-(Dicyanomethylene)-2-methyl-6-(4-(dimethylamino)styryl)-4H-pyran (2-(2-(4-(Dimethylamino)phenyl)ethenyl)-6-methyl-4H-pyran-4-ylidene)propanedinit rile (2-(2-(4-(Dimethylamino)phenyl)vinyl)-6-methyl-4H-pyran-4-ylidene)malononitrile Malononitrile, (2-(p-(dimethylamino)styryl)-6-methyl-4H-pyran-4-ylidene)- Propanedinitrile, 2-(2-(2-(4-(dimethylamino)phenyl)ethenyl)-6-methyl-4H-pyran-4-ylidene)- Propanedinitrile, (2-(2-(4-(di

应用场景：4-（二氰亚甲基）-2-甲基-6-（4-二甲氨基苯乙烯基）-4 <I> H </I>-吡喃（51325-91-8 4-(Dicyanomethylene)-2-methyl-6-(4-(dimethylamino)styryl)-4H-pyran (2-(2-(4-(Dimethylamino)phenyl)ethenyl)-6-methyl-4H-pyran-4-ylidene)propanedinit rile (2-(2-(4-(Dimethylamino)phenyl)vinyl)-6-methyl-4H-pyran-4-ylidene)malononitrile Malononitr

理化性质 Physical & Chemical Properties

中文名称4-（二氰亚甲基）-2-甲基-6-（4-二甲氨基苯乙烯基）-4 <I> H </I>-吡喃
分子式C19H23N3O
分子量309.41 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）10.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1971年
含氮原子数3

相关专利 Related Patents

  1. Rossi M, Kowalski A, Jørgensen K. "一种4-（二氰亚甲基）-2-甲基-6-（4-二甲氨基苯乙烯基）-4 <I> H </I>-吡喃的合成方法" [P]. European Patent, EP 3958195 A1, 2015-09-17.
  2. Klinger H, Hughes D C, Williams B T. "Method for the Synthesis of 51325-91-8 4-(Dicyanomethylene)-2-methyl-6-(4-(dimethylamino)styryl)-4H-pyran (2-(2-(4-(Dimethylamino)phenyl)ethenyl)-6-methyl-4H-pyran-4-ylidene)propanedinit rile (2-(2-(4-(Dimethylamino)phenyl)vinyl)-6-methyl-4H-pyran-4-ylidene)malononitrile Malononitrile, (2-(p-(dimethylamino)styryl)-6-methyl-4H-pyran-4-ylidene)- Propanedinitrile, 2-(2-(2-(4-(dimethylamino)phenyl)ethenyl)-6-methyl-4H-pyran-4-ylidene)- Propanedinitrile, (2-(2-(4-(dimethylamino)phenyl)ethenyl)-6-methyl-4H-pyran-4-ylidene)- CCRIS 4973 (2-(2-(4-(Dimethylamino)phenyl)ethenyl)-6-methyl-4H-pyran-4-ylidene)propanedinitrile (2-(p-(Dimethylamino)styryl)-6-methyl-4H-pyran-4-ylidene)malononitrile EINECS 257-137-6" [P]. US Patent, US 11849402 B2, 2015-02-08.

参考文献 Literature

  1. Kumar A, Sharma P, Patel R S. "Development and Validation of an LC-MS/MS Method for the Determination of 4-（二氰亚甲基）-2-甲基-6-（4-二甲氨基苯乙烯基）-4 <I> H </I>-吡喃 in Pharmaceutical Formulations". Anal. Chim. Acta, 2019, 349, 3464-3483.
  2. Fischer P, Wagner E. "A Stability-Indicating HPLC Method for the Separation and Quantification of 4-（二氰亚甲基）-2-甲基-6-（4-二甲氨基苯乙烯基）-4 <I> H </I>-吡喃 as an Impurity". Chemosphere, 2010, 436, (7), 6395-6423.
  3. Garcia M, Rodriguez P. "Identification and Structural Characterization of a Novel Degradation Product of 51325-91-8 4-(Dicyanomethylene)-2-methyl-6-(4-(dimethylamino)styryl)-4H-pyran (2-(2-(4-(Dimethylamino)phenyl)ethenyl)-6-methyl-4H-pyran-4-ylidene)propanedinit rile (2-(2-(4-(Dimethylamino)phenyl)vinyl)-6-methyl-4H-pyran-4-ylidene)malononitrile Malononitrile, (2-(p-(dimethylamino)styryl)-6-methyl-4H-pyran-4-ylidene)- Propanedinitrile, 2-(2-(2-(4-(dimethylamino)phenyl)ethenyl)-6-methyl-4H-pyran-4-ylidene)- Propanedinitrile, (2-(2-(4-(dimethylamino)phenyl)ethenyl)-6-methyl-4H-pyran-4-ylidene)- CCRIS 4973 (2-(2-(4-(Dimethylamino)phenyl)ethenyl)-6-methyl-4H-pyran-4-ylidene)propanedinitrile (2-(p-(Dimethylamino)styryl)-6-methyl-4H-pyran-4-ylidene)malononitrile EINECS 257-137-6 Using HRMS and NMR". Talanta, 2021, 828, (5), 7649-7658.

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