(2,4-Dimethyl-phenyl)-(4-methyl-4,5-dihydro-thiazol-2-yl)-amine CAS 519150-58-4

(2,4-Dimethyl-phenyl)-(4-methyl-4,5-dihydro-thiazol-2-yl)-amine

纯度 97%+现货药物标准品
CAS 号519150-58-4
分子式C12H16N2S
分子量220.33 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(2,4-Dimethyl-phenyl)-(4-methyl-4,5-dihydro-thiazol-2-yl)-amine (2,4-Dimethyl-phenyl)-(4-methyl-4,5-dihydro-thiazol-2-yl)-amine CAS 519150-58-4 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的(2,4-Dimethyl-phenyl)-(4-methyl-4,5-dihydro-thiazol-2-yl)-amine（(2,4-Dimethyl-phenyl)-(4-methyl-4,5-dihydro-thiazol-2-yl)-amine）为药物标准品，CAS 登记号 519150-58-4，分子式 C12H16N2S，分子量 220.33。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

与同类药物标准品相比，(2,4-Dimethyl-phenyl)-(4-methyl-4,5-dihydro-thiazol-2-yl)-amine的分子量为220.33 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 CAS编号 519150-58-4 对应的化合物(2,4-Dimethyl-phenyl)-(4-methyl-4,5-dihydro-thiazol-2-yl)-amine（英文标识 (2,4-Dimethyl-phenyl)-(4-methyl-4,5-dihydro-thiazol-2-yl)-amine），化学式 C12H16N2S，相对分子质量 220.33。 受分子结构中含氮杂环结构，含氰基，含硫有机的影响，(2,4-Dimethyl-phenyl)-(4-methyl-4,5-dihydro-thiazol-2-yl)-amine表现为类白色至淡黄色低熔点固体。（含硫化合物特征性气味）。其固体形态的物理化学属性——包括220.33 g/mol的分子量——对于选择合适的样品前处理方法和分析技术具有指导意义。分子中的氮原子赋予该化合物

应用场景：针对化学分析用途，(2,4-Dimethyl-phenyl)-(4-methyl-4,5-dihydro-thiazol-2-yl)-amine（(2,4-Dimethyl-phenyl)-(4-methyl-4,5-dihydro-thiazol-2-yl)-amine）是具有明确定量溯源的认证级对照品。 推荐以(2,4-Dimethyl-phenyl)-(4-methyl-4,5-dihydro-thiazol-2-yl)-amine配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用乙腈为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品

理化性质 Physical & Chemical Properties

中文名称(2,4-Dimethyl-phenyl)-(4-methyl-4,5-dihydro-thiazol-2-yl)-amine
分子式C12H16N2S
分子量220.33 g/mol
外观形态类白色至淡黄色低熔点固体。（含硫化合物特征性气味）
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）6.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1984年
含氮原子数2
含硫原子数1

相关专利 Related Patents

  1. Sørensen M, Martínez F, Björnsson E. "一种(2,4-Dimethyl-phenyl)-(4-methyl-4,5-dihydro-thiazol-2-yl)-amine的合成方法" [P]. European Patent, EP 3494841 A1, 2022-04-02.
  2. Nowak P, Sørensen M, Mueller T C. "Method for the Synthesis of (2,4-Dimethyl-phenyl)-(4-methyl-4,5-dihydro-thiazol-2-yl)-amine" [P]. European Patent, EP 3650667 A1, 2019-01-07.

参考文献 Literature

  1. Kim S H, Park J Y. "Development and Validation of an LC-MS/MS Method for the Determination of (2,4-Dimethyl-phenyl)-(4-methyl-4,5-dihydro-thiazol-2-yl)-amine in Pharmaceutical Formulations". Sci. Total Environ., 2022, 1053, (5), 7643-7649.
  2. Chen X Y, Liu M, Zhao W Q. "A Stability-Indicating HPLC Method for the Separation and Quantification of (2,4-Dimethyl-phenyl)-(4-methyl-4,5-dihydro-thiazol-2-yl)-amine as an Impurity". J. Chromatogr. A, 2020, 653, 4148-4174.
  3. Yang F, Sun W, Liu J. "Identification and Structural Characterization of a Novel Degradation Product of (2,4-Dimethyl-phenyl)-(4-methyl-4,5-dihydro-thiazol-2-yl)-amine Using HRMS and NMR". Rapid Commun. Mass Spectrom., 2021, 2178, (1), 1091-1118.
  4. Brown R C, Davis S M. "Forced Degradation Studies to Evaluate (2,4-Dimethyl-phenyl)-(4-methyl-4,5-dihydro-thiazol-2-yl)-amine Profile in Drug Substances According to ICH Guidelines". Anal. Chem., 2025, 141, (7), 7858-7887.

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