4-硝基苯磷酸盐 双环己铵盐 CAS 52483-84-8

52483-84-8 p-Nitrophenyl dihydrogen phosphate, compound with cyclohexylamine (1:2) Phosphoric acid, mono(4-nitrophenyl) ester, compd. with cyclohexanamine (1:2) EINECS 257-949-0 Phosphoric acid, mono(4-nitrophenyl) ester, cyclohexanamine salt (1:2)

纯度 97%+现货药物标准品
CAS 号52483-84-8
分子式C6H12NO6P 2*C6H13N
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

4-硝基苯磷酸盐 双环己铵盐 52483-84-8
p-Nitrophenyl dihydrogen phosphate, compound with cyclohexylamine (1:2)
Phosphoric acid, mono(4-nitrophenyl) ester, compd. with cyclohexanamine (1:2)
EINECS 257-949-0
Phosphoric acid, mono(4-nitrophenyl) ester, cyclohexanamine salt (1:2) CAS 52483-84-8 结构式 Chemical Structure

产品介绍 Description

CAS 52483-84-8 对应的4-硝基苯磷酸盐 双环己铵盐(52483-84-8 p-Nitrophenyl dihydrogen phosphate, compound with cyclohexylamine (1:2) Phosphoric acid, mono(4-nitrophenyl) ester, compd. with cyclohexanamine (1:2) EINECS 257-949-0 Phosphoric acid, mono(4-nitrophenyl) ester, cyclohexanamine salt (1:2))为 CATO 佳途药物标准品产品线成员。分子式 C6H12NO6P 2*C6H13N。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认,质量稳定可溯源。

4-硝基苯磷酸盐 双环己铵盐(52483-84-8 p-Nitrophenyl dihydrogen phosphate, compound with cyclohexylamine (1:2) Phosphoric acid, mono(4-nitrophenyl) ester, compd. with cyclohexanamine (1:2) EINECS 257-949-0 Phosphoric acid, mono(4-nitrophenyl) ester, cyclohexanamine salt (1:2)),CAS注册编号 52483-84-8,化学分子式为 C6H12NO6P 2C6H13N,分子量 324.31 g/mol。 4-硝基苯磷酸盐 双环己铵盐(C6H12NO6P 2C6H13N)含有酰胺类,含磷酸酯基,羧酸类,含羟基,含醚键。具有较强的吸湿性,羧基赋予其一定的酸性特征,这些物理化学性质直接决定了其标准溶液的最佳配制方案和储存策略。含氮官能团的存在使该化合物在ESI正离子模式下具有优良的离子化效率,适合LC-MS/MS分析。 在定量分析中,可作为

应用场景:针对化学分析用途,4-硝基苯磷酸盐 双环己铵盐(52483-84-8 p-Nitrophenyl dihydrogen phosphate, compound with cyclohexylamine (1:2) Phosphoric acid, mono(4-nitrophenyl) ester, compd. with cyclohexanamine (1:2) EINECS 257-949-0 Phosphoric acid, mono(4-nitrophenyl) ester, cyclohexanamine salt (1:2))是具有明确定量溯源的认证级对照品。 推荐以4-硝基苯

理化性质 Physical & Chemical Properties

中文名称4-硝基苯磷酸盐 双环己铵盐
分子式C6H12NO6P 2*C6H13N
分子量324.31 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存,避光,密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感,应避免强光直射;具有吸湿性,开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度(DBE)1.5
CAS登记年份(估)1971年
含氮原子数2

相关专利 Related Patents

  1. 发明人黄志刚,郑宇鹏,何建平. "一种4-硝基苯磷酸盐 双环己铵盐的合成方法" [P]. 中国发明专利, 专利号 CN 111974229 B, 授权公告日 2020-03-08.
  2. 发明人郭海燕,赵玉洁,王建平. "Method for the Synthesis of 52483-84-8 p-Nitrophenyl dihydrogen phosphate, compound with cyclohexylamine (1:2) Phosphoric acid, mono(4-nitrophenyl) ester, compd. with cyclohexanamine (1:2) EINECS 257-949-0 Phosphoric acid, mono(4-nitrophenyl) ester, cyclohexanamine salt (1:2)" [P]. 中国发明专利, 专利号 CN 112191720 A, 授权公告日 2019-09-07.
  3. 发明人郭海燕,郑宇鹏,何建平. "A Process for Preparing High-Purity 52483-84-8 p-Nitrophenyl dihydrogen phosphate, compound with cyclohexylamine (1:2) Phosphoric acid, mono(4-nitrophenyl) ester, compd. with cyclohexanamine (1:2) EINECS 257-949-0 Phosphoric acid, mono(4-nitrophenyl) ester, cyclohexanamine salt (1:2)" [P]. 中国发明专利, 专利号 CN 110279173 A, 授权公告日 2023-10-26.

参考文献 Literature

  1. Brown R C, Davis S M. "Development and Validation of an LC-MS/MS Method for the Determination of 4-硝基苯磷酸盐 双环己铵盐 in Pharmaceutical Formulations". Phytochemistry, 2013, 1846, 3045-3072.
  2. Fischer P, Wagner E. "A Stability-Indicating HPLC Method for the Separation and Quantification of 4-硝基苯磷酸盐 双环己铵盐 as an Impurity". Environ. Sci. Technol., 2024, 1115, (2), 7824-7828.
  3. O'Brien K, Kennedy M L. "Identification and Structural Characterization of a Novel Degradation Product of 52483-84-8 p-Nitrophenyl dihydrogen phosphate, compound with cyclohexylamine (1:2) Phosphoric acid, mono(4-nitrophenyl) ester, compd. with cyclohexanamine (1:2) EINECS 257-949-0 Phosphoric acid, mono(4-nitrophenyl) ester, cyclohexanamine salt (1:2) Using HRMS and NMR". Biomed. Chromatogr., 2012, 678, (2), 7430-7445.

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