CAS 53067-82-6

(8S,9S,10R,11R,13S,14S)-13-ethyl-11-hydroxy-1,6,7,8,9,10,11,12,13,14, (8S,9S,10R,11R,13S,14S)-13-ethyl-11-hydroxy-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-3H-cyclopenta[a]phenanthrene-3,17(2H)-dione 15,16-dodecahydro-3H-cyclopenta[a]phenanthrene-3,17(2H)-dione 53067-82-6

纯度 97%+现货药物标准品
CAS 号53067-82-6
分子式C19H26O3
分子量302.41 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(8S,9S,10R,11R,13S,14S)-13-ethyl-11-hydroxy-1,6,7,8,9,10,11,12,13,14, (8S,9S,10R,11R,13S,14S)-13-ethyl-11-hydroxy-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-3H-cyclopenta[a]phenanthrene-3,17(2H)-dione 15,16-dodecahydro-3H-cyclopenta[a]phenanthrene-3,17(2H)-dione 53067-82-6 CAS 53067-82-6 结构式 Chemical Structure

产品介绍 Description

（英文名 (8S,9S,10R,11R,13S,14S)-13-ethyl-11-hydroxy-1,6,7,8,9,10,11,12,13,14, (8S,9S,10R,11R,13S,14S)-13-ethyl-11-hydroxy-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-3H-cyclopenta[a]phenanthrene-3,17(2H)-dione 15,16-dodecahydro-3H-cyclopenta[a]phenanthrene-3,17(2H)-dione 53067-82-6，CAS 53067-82-6）属于药物标准品。分子式 C19H26O3，分子量 302.41。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

（(8S,9S,10R,11R,13S,14S)-13-ethyl-11-hydroxy-1,6,7,8,9,10,11,12,13,14, (8S,9S,10R,11R,13S,14S)-13-ethyl-11-hydroxy-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-3H-cyclopentaaphenanthrene-3,17(2H)-dione 15,16-dodecahydro-3H-cyclopentaaphenanthrene-3,17(2H)-dione 53067-82-6），CAS注册编号 53067-82-6，化学分子式为 C19H26O3，分子量 302.41 g/mol。 从化学结构特征来看，的分子骨架中包含甾体骨架，含羟基，含醚键。该化合物的不饱和度为7.0，表明结构中存在约7个环或双键等价单元。分子量为302.41 g/mol，属于较高分子量化合物。较高的碳氢原子比赋予该化合物良好的脂溶性，可使用正己烷或乙酸乙酯等非极性溶剂进行液-液萃取前处理。 在定量分析中，可作为校准标准或内标物使

应用场景：（(8S,9S,10R,11R,13S,14S)-13-ethyl-11-hydroxy-1,6,7,8,9,10,11,12,13,14, (8S,9S,10R,11R,13S,14S)-13-ethyl-11-hydroxy-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-3H-cyclopenta a phenanthrene-3,17(2H)-dione 15,16-dodecahydro-3H-cyclopenta a phenanthrene-3,17(2H)-dione 53067-82-6，CAS 53067-82-6）的标准化应用场景涵盖

理化性质 Physical & Chemical Properties

中文名称
分子式C19H26O3
分子量302.41 g/mol
外观形态类白色至淡黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）7.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1972年

相关专利 Related Patents

  1. 发明人马晓峰，张德明，孙丽萍. "一种的合成方法" [P]. 中国发明专利, 专利号 CN 113137280 B, 授权公告日 2022-07-18.
  2. Brown S R, Johnson M A, Davis P L. "Method for the Synthesis of (8S,9S,10R,11R,13S,14S)-13-ethyl-11-hydroxy-1,6,7,8,9,10,11,12,13,14, (8S,9S,10R,11R,13S,14S)-13-ethyl-11-hydroxy-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-3H-cyclopenta[a]phenanthrene-3,17(2H)-dione 15,16-dodecahydro-3H-cyclopenta[a]phenanthrene-3,17(2H)-dione 53067-82-6" [P]. US Patent, US 11505953 B2, 2016-01-27.

参考文献 Literature

  1. Xu M, Hu Y, Zhou D. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". Anal. Chim. Acta, 2021, 1550, (11), 9427-9451.
  2. Kumar A, Sharma P, Patel R S. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". Rapid Commun. Mass Spectrom., 2020, 107, (11), 6681-6708.
  3. Xu M, Hu Y, Zhou D. "Identification and Structural Characterization of a Novel Degradation Product of (8S,9S,10R,11R,13S,14S)-13-ethyl-11-hydroxy-1,6,7,8,9,10,11,12,13,14, (8S,9S,10R,11R,13S,14S)-13-ethyl-11-hydroxy-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-3H-cyclopenta[a]phenanthrene-3,17(2H)-dione 15,16-dodecahydro-3H-cyclopenta[a]phenanthrene-3,17(2H)-dione 53067-82-6 Using HRMS and NMR". Anal. Methods, 2025, 1243, 8-34.

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