CAS 532-77-4
(2-Cyclohexylamino-1-methylethyl) benzoate 1-(Cyclohexylamino)-2-propanol benzoate (ester) 1-(cyclohexylamino)propan-2-yl benzoate 2-Propanol, 1-(cyclohexylamino)-, benzoate (ester) 532-77-4 Cyclaine (TN) D08MRN Hexilcaina Hexilcaina [INN-Spanish] Hexylcaine Hexylcaine [INN] Hexylcainum Hexylcainum [INN-Latin] Osmocaine Osmocaine (TN)
| CAS 号 | 532-77-4 |
| 分子式 | C16H23NO2 |
| 分子量 | 261.36 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
（(2-Cyclohexylamino-1-methylethyl) benzoate 1-(Cyclohexylamino)-2-propanol benzoate (ester) 1-(cyclohexylamino)propan-2-yl benzoate 2-Propanol, 1-(cyclohexylamino)-, benzoate (ester) 532-77-4 Cyclaine (TN) D08MRN Hexilcaina Hexilcaina [INN-Spanish] Hexylcaine Hexylcaine [INN] Hexylcainum Hexylcainum [INN-Latin] Osmocaine Osmocaine (TN)）是药物分析与质量控制领域常用的药物标准品，CAS 号 532-77-4。分子式 C16H23NO2，分子量 261.36。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。
CAS编号 532-77-4 对应的化合物（英文标识 (2-Cyclohexylamino-1-methylethyl) benzoate 1-(Cyclohexylamino)-2-propanol benzoate (ester) 1-(cyclohexylamino)propan-2-yl benzoate 2-Propanol, 1-(cyclohexylamino)-, benzoate (ester) 532-77-4 Cyclaine (TN) D08MRN Hexilcaina Hexilcaina INN-Spanish Hexylcaine Hexylcaine INN Hexylcainum Hexylcainum INN-Latin Osmocaine Osmocaine (TN)），化学式 C16H23NO2，相对分子质量 261.36。 （C16H23NO2）含有含氮杂环结构，酰胺类，含羟基，含醚键。较高的碳氢比使其脂溶性较好，羧基赋予其一定的酸性特征，这些物理化学性质直接决定了其标准溶液的最佳配制方案和储存策略。分子中包含芳环或共轭体系，在U
应用场景：（(2-Cyclohexylamino-1-methylethyl) benzoate 1-(Cyclohexylamino)-2-propanol benzoate (ester) 1-(cyclohexylamino)propan-2-yl benzoate 2-Propanol, 1-(cyclohexylamino)-, benzoate (ester) 532-77-4 Cyclaine (TN) D08MRN Hexilcaina Hexilcaina INN-Spanish Hexylcaine Hexylcaine INN Hexylcainum Hexylcainum
理化性质 Physical & Chemical Properties
| 中文名称 | |
| 分子式 | C16H23NO2 |
| 分子量 | 261.36 g/mol |
| 外观形态 | 类白色至淡黄色结晶性粉末 |
| 纯度 | 97%+ |
| 储存条件 | 2-8°C冷藏保存，避光 |
| 溶解性参考 | 可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO |
| 稳定性 | 空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 6.0 |
| UV特征 | 有紫外吸收 |
| 结构特征 | 含芳环 |
| CAS登记年份（估） | 1957年 |
| 含氮原子数 | 1 |
相关专利 Related Patents
- 发明人林芳，周伟，韩伟. "一种的合成方法" [P]. 中国发明专利, 专利号 CN 111298274 B, 授权公告日 2016-09-02.
- 发明人唐晓军，刘建华，李文辉. "Method for the Synthesis of (2-Cyclohexylamino-1-methylethyl) benzoate 1-(Cyclohexylamino)-2-propanol benzoate (ester) 1-(cyclohexylamino)propan-2-yl benzoate 2-Propanol, 1-(cyclohexylamino)-, benzoate (ester) 532-77-4 Cyclaine (TN) D08MRN Hexilcaina Hexilcaina [INN-Spanish] Hexylcaine Hexylcaine [INN] Hexylcainum Hexylcainum [INN-Latin] Osmocaine Osmocaine (TN)" [P]. 中国发明专利, 专利号 CN 112073649 A, 授权公告日 2019-12-16.
- Williams B T, Stevens L M, Mueller T. "A Process for Preparing High-Purity (2-Cyclohexylamino-1-methylethyl) benzoate 1-(Cyclohexylamino)-2-propanol benzoate (ester) 1-(cyclohexylamino)propan-2-yl benzoate 2-Propanol, 1-(cyclohexylamino)-, benzoate (ester) 532-77-4 Cyclaine (TN) D08MRN Hexilcaina Hexilcaina [INN-Spanish] Hexylcaine Hexylcaine [INN] Hexylcainum Hexylcainum [INN-Latin] Osmocaine Osmocaine (TN)" [P]. US Patent, US 9730920 B2, 2021-07-05.
参考文献 Literature
- Kumar A, Sharma P, Patel R S. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". Talanta, 2013, 1102, (11), 9377-9407.
- Jensen P, Larsen A M, Olsen K. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". Anal. Chim. Acta, 2014, 1158, (11), 6506-6513.
- Lee J H, Choi Y S. "Identification and Structural Characterization of a Novel Degradation Product of (2-Cyclohexylamino-1-methylethyl) benzoate 1-(Cyclohexylamino)-2-propanol benzoate (ester) 1-(cyclohexylamino)propan-2-yl benzoate 2-Propanol, 1-(cyclohexylamino)-, benzoate (ester) 532-77-4 Cyclaine (TN) D08MRN Hexilcaina Hexilcaina [INN-Spanish] Hexylcaine Hexylcaine [INN] Hexylcainum Hexylcainum [INN-Latin] Osmocaine Osmocaine (TN) Using HRMS and NMR". J. Sep. Sci., 2019, 2041, 5855-5861.
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