(±)-2-乙酰氧基丙酸 CAS 535-17-1

535-17-1 alpha-Acetolactate Lactic acid, acetate (8CI) Propanoic acid, 2-(acetyloxy)- Acetolactate 2-Acetoxypropanoic acid alpha-Acetoxypropionic acid 2-Acetoxypropionic acid Acetyllactic acid O-Acetyllactic acid AI3-03136 NSC 402126

纯度 97%+现货药物标准品
CAS 号535-17-1
分子式C5H8O4
分子量132.11 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(±)-2-乙酰氧基丙酸 535-17-1 alpha-Acetolactate Lactic acid, acetate (8CI) Propanoic acid, 2-(acetyloxy)- Acetolactate 2-Acetoxypropanoic acid alpha-Acetoxypropionic acid 2-Acetoxypropionic acid Acetyllactic acid O-Acetyllactic acid AI3-03136 NSC 402126 CAS 535-17-1 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的(±)-2-乙酰氧基丙酸（535-17-1 alpha-Acetolactate Lactic acid, acetate (8CI) Propanoic acid, 2-(acetyloxy)- Acetolactate 2-Acetoxypropanoic acid alpha-Acetoxypropionic acid 2-Acetoxypropionic acid Acetyllactic acid O-Acetyllactic acid AI3-03136 NSC 402126）为药物标准品，CAS 登记号 535-17-1，分子式 C5H8O4，分子量 132.11。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

推荐用于分析方法开发与验证，产品提供完整COA证书，确保ISO 17034标准的量值溯源要求。适用于GLP实验室的日常分析。 化学式为 C5H8O4 的(±)-2-乙酰氧基丙酸（535-17-1 alpha-Acetolactate Lactic acid, acetate (8CI) Propanoic acid, 2-(acetyloxy)- Acetolactate 2-Acetoxypropanoic acid alpha-Acetoxypropionic acid 2-Acetoxypropionic acid Acetyllactic acid O-Acetyllactic acid AI3-03136 NSC 402126），其CAS登记号是 535-17-1，分子量为 132.11 g/mol。 (±)-2-乙酰氧基丙酸（C5H8O4）含有糖类衍生物。具有较强的吸湿性，羧基赋予其一定的酸性特征，这些物理化学性质直接决定了其标准溶液的最佳配制方案和储存策略。 本品定值报告包含以下质量控制信息： - 主成分含量：97%+； - 水分/残留溶

应用场景：针对化学分析用途，(±)-2-乙酰氧基丙酸（535-17-1 alpha-Acetolactate Lactic acid, acetate (8CI) Propanoic acid, 2-(acetyloxy)- Acetolactate 2-Acetoxypropanoic acid alpha-Acetoxypropionic acid 2-Acetoxypropionic acid Acetyllactic acid O-Acetyllactic acid AI3-03136 NSC 402126）是具有明确定量溯源的认证级对照品。 推荐以(±)-2-乙酰氧基丙酸配制标准系列工作溶液

理化性质 Physical & Chemical Properties

中文名称(±)-2-乙酰氧基丙酸
分子式C5H8O4
分子量132.11 g/mol
外观形态白色至类白色液体
纯度97%+
储存条件2-8°C冷藏保存，密封防潮
溶解性参考可溶于甲醇、乙醇、DMSO、水
稳定性具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.0
CAS登记年份（估）1957年

相关专利 Related Patents

  1. Mueller T C, Björnsson E, Nielsen H. "一种(±)-2-乙酰氧基丙酸的合成方法" [P]. European Patent, EP 3173121 A1, 2023-07-23.
  2. 发明人韩伟，李文辉，林芳. "Method for the Synthesis of 535-17-1 alpha-Acetolactate Lactic acid, acetate (8CI) Propanoic acid, 2-(acetyloxy)- Acetolactate 2-Acetoxypropanoic acid alpha-Acetoxypropionic acid 2-Acetoxypropionic acid Acetyllactic acid O-Acetyllactic acid AI3-03136 NSC 402126" [P]. 中国发明专利, 专利号 CN 113702702 A, 授权公告日 2016-11-11.
  3. 发明人郭海燕，李文辉，钱学锋. "A Process for Preparing High-Purity 535-17-1 alpha-Acetolactate Lactic acid, acetate (8CI) Propanoic acid, 2-(acetyloxy)- Acetolactate 2-Acetoxypropanoic acid alpha-Acetoxypropionic acid 2-Acetoxypropionic acid Acetyllactic acid O-Acetyllactic acid AI3-03136 NSC 402126" [P]. 中国发明专利, 专利号 CN 111243212 B, 授权公告日 2022-04-09.

参考文献 Literature

  1. Kim S H, Park J Y. "Development and Validation of an LC-MS/MS Method for the Determination of (±)-2-乙酰氧基丙酸 in Pharmaceutical Formulations". Chromatographia, 2019, 2109, 9042-9057.
  2. Yang F, Sun W, Liu J. "A Stability-Indicating HPLC Method for the Separation and Quantification of (±)-2-乙酰氧基丙酸 as an Impurity". Talanta, 2017, 2142, (12), 9926-9954.
  3. Fischer P, Wagner E. "Identification and Structural Characterization of a Novel Degradation Product of 535-17-1 alpha-Acetolactate Lactic acid, acetate (8CI) Propanoic acid, 2-(acetyloxy)- Acetolactate 2-Acetoxypropanoic acid alpha-Acetoxypropionic acid 2-Acetoxypropionic acid Acetyllactic acid O-Acetyllactic acid AI3-03136 NSC 402126 Using HRMS and NMR". Molecules, 2023, 1034, (11), 1584-1607.
  4. Yang F, Sun W, Liu J. "Forced Degradation Studies to Evaluate (±)-2-乙酰氧基丙酸 Profile in Drug Substances According to ICH Guidelines". J. Pharm. Biomed. Anal., 2018, 1056, 3863-3875.

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