苄基异硫脲 盐酸盐 CAS 538-28-3
538-28-3 QJ9N8049ND S-Benzylthiuronium chloride S-Benzylthiouronium chloride Carbamidothioic acid, phenylmethyl ester, monohydrochloride Pseudourea, 2-benzyl-2-thio-, monohydrochloride Carbamimidothioic acid, phenylmethyl ester, hydrochloride (1:1) Carbamimidothioic acid, phenylmethyl ester, monohydrochloride A-287 X 182 AI3-17804 Benzyl thiopseudourea hydrochloride Benzylisothiourea hydrochloride S-Benzylisothiourea hydrochloride Benzylisothiouronium chloride 2-Benzylisothiouronium chloride Benzylisothiuronium chloride S-Benzylthioformamidine hydrochloride S-Benzylthiopseudourea hydrochloride Benzylthiuronium chloride BTKH EINECS 208-688-6 Isothiouronium chloride, benzyl- NSC 179799 Pseudourea, 2-benzyl-2-thio-, hydrochloride Pseudourea, 2-thio-2-benzyl-, hydrochloride TL 944 USAF EK-2124 UNII-QJ9N8049ND
| CAS 号 | 538-28-3 |
| 分子式 | C8H16N2S HCl |
| 分子量 | N/A g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
苄基异硫脲 盐酸盐（英文名 538-28-3 QJ9N8049ND S-Benzylthiuronium chloride S-Benzylthiouronium chloride Carbamidothioic acid, phenylmethyl ester, monohydrochloride Pseudourea, 2-benzyl-2-thio-, monohydrochloride Carbamimidothioic acid, phenylmethyl ester, hydrochloride (1:1) Carbamimidothioic acid, phenylmethyl ester, monohydrochloride A-287 X 182 AI3-17804 Benzyl thiopseudourea hydrochloride Benzylisothiourea hydrochloride S-Benzylisothiourea hydrochloride Benzylisothiouronium chloride 2-Benzylisothiouronium chloride Benzylisothiuronium chloride S-Benzylthioformamidine hydrochloride S-Benzylthiopseudourea hydrochloride Benzylthiuronium chloride BTKH EINECS 208-688-6 Isothiouronium chloride, benzyl- NSC 179799 Pseudourea, 2-benzyl-2-thio-, hydrochloride Pseudourea, 2-thio-2-benzyl-, hydrochloride TL 944 USAF EK-2124 UNII-QJ9N8049ND，CAS 538-28-3）属于药物标准品。分子式 C8H16N2S HCl。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。
与同类药物标准品相比，苄基异硫脲 盐酸盐的分子量为208.75 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 CAS编号 538-28-3 对应的化合物苄基异硫脲 盐酸盐（英文标识 538-28-3 QJ9N8049ND S-Benzylthiuronium chloride S-Benzylthiouronium chloride Carbamidothioic acid, phenylmethyl ester, monohydrochloride Pseudourea, 2-benzyl-2-thio-, monohydrochloride Carbamimidothioic acid, phenylmethyl ester, hydrochloride (1:1) Carbamimidothioic acid, phenylmethyl ester, monohydrochloride A-287 X 182 AI3-17804 Benzyl thiopseudourea hydrochloride Benzylisothiourea hydrochlo
应用场景：从实际应用出发，苄基异硫脲 盐酸盐（CAS 538-28-3）在化学分析中作为关键的基准对照物质。 推荐以苄基异硫脲 盐酸盐配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用甲醇配制，于2-8°C冷藏保存，避光，密闭保存防止挥发条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用，防止吸潮影响称量准确性。
理化性质 Physical & Chemical Properties
| 中文名称 | 苄基异硫脲 盐酸盐 |
| 分子式 | C8H16N2S HCl |
| 分子量 | 208.75 g/mol |
| 外观形态 | 白色至类白色结晶性粉末。（具有轻微卤代物特征气味，具有氨/胺类微弱气味，含硫化合物特征性气味） |
| 纯度 | 97%+ |
| 储存条件 | 2-8°C冷藏保存，避光，密闭保存防止挥发 |
| 溶解性参考 | 可溶于DMSO、DMF、甲醇 |
| 稳定性 | 对光敏感，应避免强光直射 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 1.0 |
| CAS登记年份（估） | 1957年 |
| 卤素含量 | Cl取代 |
| 含氮原子数 | 2 |
| 含硫原子数 | 1 |
相关专利 Related Patents
- 发明人韩伟，林芳，郭海燕. "一种苄基异硫脲 盐酸盐的合成方法" [P]. 中国发明专利, 专利号 CN 110192540 A, 授权公告日 2018-04-13.
- 发明人冯建国，孙丽萍，刘建华. "Method for the Synthesis of 538-28-3 QJ9N8049ND S-Benzylthiuronium chloride S-Benzylthiouronium chloride Carbamidothioic acid, phenylmethyl ester, monohydrochloride Pseudourea, 2-benzyl-2-thio-, monohydrochloride Carbamimidothioic acid, phenylmethyl ester, hydrochloride (1:1) Carbamimidothioic acid, phenylmethyl ester, monohydrochloride A-287 X 182 AI3-17804 Benzyl thiopseudourea hydrochloride Benzylisothiourea hydrochloride S-Benzylisothiourea hydrochloride Benzylisothiouronium chloride 2-Benzylisothiouronium chloride Benzylisothiuronium chloride S-Benzylthioformamidine hydrochloride S-Benzylthiopseudourea hydrochloride Benzylthiuronium chloride BTKH EINECS 208-688-6 Isothiouronium chloride, benzyl- NSC 179799 Pseudourea, 2-benzyl-2-thio-, hydrochloride Pseudourea, 2-thio-2-benzyl-, hydrochloride TL 944 USAF EK-2124 UNII-QJ9N8049ND" [P]. 中国发明专利, 专利号 CN 111438790 B, 授权公告日 2015-05-11.
- 发明人徐明华，黄志刚，刘建华. "A Process for Preparing High-Purity 538-28-3 QJ9N8049ND S-Benzylthiuronium chloride S-Benzylthiouronium chloride Carbamidothioic acid, phenylmethyl ester, monohydrochloride Pseudourea, 2-benzyl-2-thio-, monohydrochloride Carbamimidothioic acid, phenylmethyl ester, hydrochloride (1:1) Carbamimidothioic acid, phenylmethyl ester, monohydrochloride A-287 X 182 AI3-17804 Benzyl thiopseudourea hydrochloride Benzylisothiourea hydrochloride S-Benzylisothiourea hydrochloride Benzylisothiouronium chloride 2-Benzylisothiouronium chloride Benzylisothiuronium chloride S-Benzylthioformamidine hydrochloride S-Benzylthiopseudourea hydrochloride Benzylthiuronium chloride BTKH EINECS 208-688-6 Isothiouronium chloride, benzyl- NSC 179799 Pseudourea, 2-benzyl-2-thio-, hydrochloride Pseudourea, 2-thio-2-benzyl-, hydrochloride TL 944 USAF EK-2124 UNII-QJ9N8049ND" [P]. 中国发明专利, 专利号 CN 115200964 A, 授权公告日 2016-08-17.
参考文献 Literature
- Xu M, Hu Y, Zhou D. "Development and Validation of an LC-MS/MS Method for the Determination of 苄基异硫脲 盐酸盐 in Pharmaceutical Formulations". Food Chem., 2012, 1790, (7), 6391-6396.
- Xu M, Hu Y, Zhou D. "A Stability-Indicating HPLC Method for the Separation and Quantification of 苄基异硫脲 盐酸盐 as an Impurity". Chromatographia, 2018, 147, (8), 3268-3286.
- Garcia M, Rodriguez P. "Identification and Structural Characterization of a Novel Degradation Product of 538-28-3 QJ9N8049ND S-Benzylthiuronium chloride S-Benzylthiouronium chloride Carbamidothioic acid, phenylmethyl ester, monohydrochloride Pseudourea, 2-benzyl-2-thio-, monohydrochloride Carbamimidothioic acid, phenylmethyl ester, hydrochloride (1:1) Carbamimidothioic acid, phenylmethyl ester, monohydrochloride A-287 X 182 AI3-17804 Benzyl thiopseudourea hydrochloride Benzylisothiourea hydrochloride S-Benzylisothiourea hydrochloride Benzylisothiouronium chloride 2-Benzylisothiouronium chloride Benzylisothiuronium chloride S-Benzylthioformamidine hydrochloride S-Benzylthiopseudourea hydrochloride Benzylthiuronium chloride BTKH EINECS 208-688-6 Isothiouronium chloride, benzyl- NSC 179799 Pseudourea, 2-benzyl-2-thio-, hydrochloride Pseudourea, 2-thio-2-benzyl-, hydrochloride TL 944 USAF EK-2124 UNII-QJ9N8049ND Using HRMS and NMR". Anal. Chim. Acta, 2022, 1278, (5), 6947-6951.
- Kim S H, Park J Y. "Forced Degradation Studies to Evaluate 苄基异硫脲 盐酸盐 Profile in Drug Substances According to ICH Guidelines". Phytochemistry, 2023, 2308, 9985-10015.
推荐产品 Recommended Standards
- 2-Allyl-3-hydroxy-3-phenylisoindolin-1-one (CAS 3532-75-0)
- 4,5,6,7-Tetrahydro-1-methyl-3-(trifluoromethyl)-1H-pyrazolo[4,3-c]pyridine (CAS 794451-94-8)
- 2-Chloro-5,6-dihydro-4H-cyclopenta[b]thiophen-4-one (CAS 69300-48-7)
- 6,7-Dimethoxy-2-(trifluoromethyl)-4H-benzo[d][1,3]oxazin-4-one (CAS 95274-63-8)
- 6,7-Dimethoxy-2-(4-nitrophenyl)-3,4-dihydronaphthalen-1(2H)-one (CAS 1451449-53-8)
- 2-(3,5-Dimethoxyphenyl)acetohydrazide (CAS 1824064-37-0)
- Des-Gly34-替尔泊肽 (CAS CATO-CPTD788940)
为什么选择 CATO 佳途？
- ISO 17034 / CNAS / ANAB 三重认证标准物质生产商
- 130,000+ 品种现货库存，支持 COA 定制
- 专业技术支持：+86 13829788188 / jacky.chen@cato-chem.com
- 全球 10,000+ 客户信赖之选