间苯二胺 二盐酸盐 CAS 541-69-5

541-69-5 SE5RLO93TG 1,3-Benzenediamine dihydrochloride m-Phenylenediamine, dihydrochloride 1,3-Benzenediamine, hydrochloride (1:2) 1,3-Benzenediamine, dihydrochloride meta-Aminoaniline dihydrochloride m-Aminoaniline dihydrochloride 3-Aminoaniline dihydrochloride meta-Benzenediamine dihydrochloride m-Benzenediamine dihydrochloride 1,3-Benzenediamine hydrochloride meta-Diaminobenzene dihydrochloride m-Diaminobenzene dihydrochloride 1,3-Diaminobenzene dihydrochloride EINECS 208-790-0 HSDB 6237 1,3-Phenylenediamine dihydrochloride m-Phenylenediamine hydrochloride USAF EK-206 m-Phenylenediamine dihydrochloride CCRIS 9436 UNII-SE5RLO93TG meta-Phenylenediamine (hydrochloride)

纯度 97%+现货药物标准品
CAS 号541-69-5
分子式C6H14N2 2*HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

间苯二胺 二盐酸盐 541-69-5 SE5RLO93TG 1,3-Benzenediamine dihydrochloride m-Phenylenediamine, dihydrochloride 1,3-Benzenediamine, hydrochloride (1:2) 1,3-Benzenediamine, dihydrochloride meta-Aminoaniline dihydrochloride m-Aminoaniline dihydrochloride 3-Aminoaniline dihydrochloride meta-Benzenediamine dihydrochloride m-Benzenediamine dihydrochloride 1,3-Benzenediamine hydrochloride meta-Diaminobenzene dihydrochloride m-Diaminobenzene dihydrochloride 1,3-Diaminobenzene dihydrochloride EINECS 208-790-0 HSDB 6237 1,3-Phenylenediamine dihydrochloride m-Phenylenediamine hydrochloride USAF EK-206 m-Phenylenediamine dihydrochloride CCRIS 9436 UNII-SE5RLO93TG meta-Phenylenediamine (hydrochloride) CAS 541-69-5 结构式 Chemical Structure

产品介绍 Description

间苯二胺 二盐酸盐（541-69-5 SE5RLO93TG 1,3-Benzenediamine dihydrochloride m-Phenylenediamine, dihydrochloride 1,3-Benzenediamine, hydrochloride (1:2) 1,3-Benzenediamine, dihydrochloride meta-Aminoaniline dihydrochloride m-Aminoaniline dihydrochloride 3-Aminoaniline dihydrochloride meta-Benzenediamine dihydrochloride m-Benzenediamine dihydrochloride 1,3-Benzenediamine hydrochloride meta-Diaminobenzene dihydrochloride m-Diaminobenzene dihydrochloride 1,3-Diaminobenzene dihydrochloride EINECS 208-790-0 HSDB 6237 1,3-Phenylenediamine dihydrochloride m-Phenylenediamine hydrochloride USAF EK-206 m-Phenylenediamine dihydrochloride CCRIS 9436 UNII-SE5RLO93TG meta-Phenylenediamine (hydrochloride)，CAS 号 541-69-5）是 CATO 佳途自主生产的药物标准品，分子式 C6H14N2 2*HCl。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

在定量分析中，可作为校准标准或内标物使用，适用于多种检测技术平台（UV-Vis, FLD, MS, FID）。 化学式为 C6H14N2 2HCl 的间苯二胺 二盐酸盐（541-69-5 SE5RLO93TG 1,3-Benzenediamine dihydrochloride m-Phenylenediamine, dihydrochloride 1,3-Benzenediamine, hydrochloride (1:2) 1,3-Benzenediamine, dihydrochloride meta-Aminoaniline dihydrochloride m-Aminoaniline dihydrochloride 3-Aminoaniline dihydrochloride meta-Benzenediamine dihydrochloride m-Benzenediamine dihydrochloride 1,3-Benzenediamine hydrochloride meta-Diaminobenzene dihydrochloride m-Di

应用场景：在化学分析实验室中，间苯二胺 二盐酸盐（CAS 541-69-5）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以间苯二胺 二盐酸盐配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用甲醇配制，于2-8°C冷藏保存，避光，密闭保存防止挥发条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用，防止吸潮影响称量准确性。

理化性质 Physical & Chemical Properties

中文名称间苯二胺 二盐酸盐
分子式C6H14N2 2*HCl
分子量150.65 g/mol
外观形态白色至类白色结晶性粉末。（具有轻微卤代物特征气味，具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密闭保存防止挥发
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）0.0
CAS登记年份（估）1957年
卤素含量Cl取代
含氮原子数2

相关专利 Related Patents

  1. 发明人孙丽萍，林芳，徐明华. "一种间苯二胺 二盐酸盐的合成方法" [P]. 中国发明专利, 专利号 CN 114864362 A, 授权公告日 2022-11-18.
  2. 发明人赵玉洁，张德明，何建平. "Method for the Synthesis of 541-69-5 SE5RLO93TG 1,3-Benzenediamine dihydrochloride m-Phenylenediamine, dihydrochloride 1,3-Benzenediamine, hydrochloride (1:2) 1,3-Benzenediamine, dihydrochloride meta-Aminoaniline dihydrochloride m-Aminoaniline dihydrochloride 3-Aminoaniline dihydrochloride meta-Benzenediamine dihydrochloride m-Benzenediamine dihydrochloride 1,3-Benzenediamine hydrochloride meta-Diaminobenzene dihydrochloride m-Diaminobenzene dihydrochloride 1,3-Diaminobenzene dihydrochloride EINECS 208-790-0 HSDB 6237 1,3-Phenylenediamine dihydrochloride m-Phenylenediamine hydrochloride USAF EK-206 m-Phenylenediamine dihydrochloride CCRIS 9436 UNII-SE5RLO93TG meta-Phenylenediamine (hydrochloride)" [P]. 中国发明专利, 专利号 CN 113780241 A, 授权公告日 2023-06-17.
  3. 发明人张德明，赵玉洁，郭海燕. "A Process for Preparing High-Purity 541-69-5 SE5RLO93TG 1,3-Benzenediamine dihydrochloride m-Phenylenediamine, dihydrochloride 1,3-Benzenediamine, hydrochloride (1:2) 1,3-Benzenediamine, dihydrochloride meta-Aminoaniline dihydrochloride m-Aminoaniline dihydrochloride 3-Aminoaniline dihydrochloride meta-Benzenediamine dihydrochloride m-Benzenediamine dihydrochloride 1,3-Benzenediamine hydrochloride meta-Diaminobenzene dihydrochloride m-Diaminobenzene dihydrochloride 1,3-Diaminobenzene dihydrochloride EINECS 208-790-0 HSDB 6237 1,3-Phenylenediamine dihydrochloride m-Phenylenediamine hydrochloride USAF EK-206 m-Phenylenediamine dihydrochloride CCRIS 9436 UNII-SE5RLO93TG meta-Phenylenediamine (hydrochloride)" [P]. 中国发明专利, 专利号 CN 112877495 A, 授权公告日 2021-05-18.

参考文献 Literature

  1. Yang F, Sun W, Liu J. "Development and Validation of an LC-MS/MS Method for the Determination of 间苯二胺 二盐酸盐 in Pharmaceutical Formulations". J. Nat. Prod., 2018, 1343, (2), 6201-6224.
  2. Kim S H, Park J Y. "A Stability-Indicating HPLC Method for the Separation and Quantification of 间苯二胺 二盐酸盐 as an Impurity". Chemosphere, 2019, 250, (12), 8784-8812.
  3. Wang L, Li J, Zhang H. "Identification and Structural Characterization of a Novel Degradation Product of 541-69-5 SE5RLO93TG 1,3-Benzenediamine dihydrochloride m-Phenylenediamine, dihydrochloride 1,3-Benzenediamine, hydrochloride (1:2) 1,3-Benzenediamine, dihydrochloride meta-Aminoaniline dihydrochloride m-Aminoaniline dihydrochloride 3-Aminoaniline dihydrochloride meta-Benzenediamine dihydrochloride m-Benzenediamine dihydrochloride 1,3-Benzenediamine hydrochloride meta-Diaminobenzene dihydrochloride m-Diaminobenzene dihydrochloride 1,3-Diaminobenzene dihydrochloride EINECS 208-790-0 HSDB 6237 1,3-Phenylenediamine dihydrochloride m-Phenylenediamine hydrochloride USAF EK-206 m-Phenylenediamine dihydrochloride CCRIS 9436 UNII-SE5RLO93TG meta-Phenylenediamine (hydrochloride) Using HRMS and NMR". Anal. Chim. Acta, 2011, 474, 4229-4234.
  4. Fischer P, Wagner E. "Forced Degradation Studies to Evaluate 间苯二胺 二盐酸盐 Profile in Drug Substances According to ICH Guidelines". Anal. Chem., 2018, 498, 1735-1738.

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