6-hydrazinyl-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione CAS 54317-65-6

6-hydrazinyl-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione

纯度 97%+现货药物标准品
CAS 号54317-65-6
分子式C5H9N5O2
分子量171.16 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

6-hydrazinyl-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione 6-hydrazinyl-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione CAS 54317-65-6 结构式 Chemical Structure

产品介绍 Description

CAS 54317-65-6 对应的6-hydrazinyl-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione（6-hydrazinyl-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione）为 CATO 佳途药物标准品产品线成员。分子式 C5H9N5O2，分子量 171.16。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

受分子结构中氨基酸衍生物，酰胺类，含羟基，含醚键的影响，6-hydrazinyl-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione表现为类白色至淡黄色结晶性粉末。（具有氨/胺类微弱气味）。其固体形态的物理化学属性——包括171.16 g/mol的分子量——对于选择合适的样品前处理方法和分析技术具有指导意义。分子中包含芳环或共轭体系，在UV-Vis光谱中具有特征性吸收带，适用于紫外或二极管阵列检测器（DAD）的定量分析。 CAS编号 54317-65-6 对应的化合物6-hydrazinyl-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione（英文标识 6-hydrazinyl-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione），化学式 C5H9N5O2，相对分子质量 171.16。 在定量分析中，可作为校准标准或内标物使用，适用于多种检测技术平台（UV-Vis, FLD, MS,

应用场景：从实际应用出发，6-hydrazinyl-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione（CAS 54317-65-6）在化学分析中作为关键的基准对照物质。 推荐以6-hydrazinyl-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈（1:1）为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用甲

理化性质 Physical & Chemical Properties

中文名称6-hydrazinyl-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione
分子式C5H9N5O2
分子量171.16 g/mol
外观形态类白色至淡黄色结晶性粉末。（具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）4.0
UV特征有紫外吸收
CAS登记年份（估）1972年
含氮原子数5

相关专利 Related Patents

  1. O'Brien P Q, Park J H, Kumar R. "一种6-hydrazinyl-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione的合成方法" [P]. US Patent, US 10478855 B2, 2023-07-26.
  2. 发明人郭海燕，孙丽萍，陈志强. "Method for the Synthesis of 6-hydrazinyl-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione" [P]. 中国发明专利, 专利号 CN 114392133 B, 授权公告日 2018-08-22.
  3. 发明人张德明，周伟，钱学锋. "A Process for Preparing High-Purity 6-hydrazinyl-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione" [P]. 中国发明专利, 专利号 CN 116890148 B, 授权公告日 2019-09-18.

参考文献 Literature

  1. Fischer P, Wagner E. "Development and Validation of an LC-MS/MS Method for the Determination of 6-hydrazinyl-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione in Pharmaceutical Formulations". Biomed. Chromatogr., 2025, 1520, 6122-6140.
  2. Brown R C, Davis S M. "A Stability-Indicating HPLC Method for the Separation and Quantification of 6-hydrazinyl-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione as an Impurity". J. Sep. Sci., 2015, 1703, (8), 4384-4393.
  3. Xu M, Hu Y, Zhou D. "Identification and Structural Characterization of a Novel Degradation Product of 6-hydrazinyl-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione Using HRMS and NMR". J. Agric. Food Chem., 2022, 592, 198-214.
  4. Jensen P, Larsen A M, Olsen K. "Forced Degradation Studies to Evaluate 6-hydrazinyl-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione Profile in Drug Substances According to ICH Guidelines". Chromatographia, 2025, 1797, (9), 9284-9314.

Related hydrazinyl Standards 同系列产品

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...