Coumarin 314 CAS 55804-66-5

55804-66-5 WM5MO60RUO Coumarin 504 1H,5H,11H-(1)Benzopyrano(6,7,8-ij)quinolizine-10-carboxylic acid, 2,3,6,7-tetrahydro-11-oxo-, ethyl ester Ethyl 2,3,6,7-tetrahydro-11-oxo-1H,5H,11H-(1)benzopyrano(6,7,8-ij)quinolizine-10-carboxylate CCRIS 4963 EINECS 259-825-1 NSC 338967 UNII-WM5MO60RUO

纯度 97%+现货药物标准品
CAS 号55804-66-5
分子式C18H25NO4
分子量319.40 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

Coumarin 314 55804-66-5 WM5MO60RUO Coumarin 504 1H,5H,11H-(1)Benzopyrano(6,7,8-ij)quinolizine-10-carboxylic acid, 2,3,6,7-tetrahydro-11-oxo-, ethyl ester Ethyl 2,3,6,7-tetrahydro-11-oxo-1H,5H,11H-(1)benzopyrano(6,7,8-ij)quinolizine-10-carboxylate CCRIS 4963 EINECS 259-825-1 NSC 338967 UNII-WM5MO60RUO CAS 55804-66-5 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品Coumarin 314（55804-66-5 WM5MO60RUO Coumarin 504 1H,5H,11H-(1)Benzopyrano(6,7,8-ij)quinolizine-10-carboxylic acid, 2,3,6,7-tetrahydro-11-oxo-, ethyl ester Ethyl 2,3,6,7-tetrahydro-11-oxo-1H,5H,11H-(1)benzopyrano(6,7,8-ij)quinolizine-10-carboxylate CCRIS 4963 EINECS 259-825-1 NSC 338967 UNII-WM5MO60RUO，CAS 55804-66-5），分子式 C18H25NO4，分子量 319.40。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括Coumarin 314在内的目标物的控制。 化学式为 C18H25NO4 的Coumarin 314（55804-66-5 WM5MO60RUO Coumarin 504 1H,5H,11H-(1)Benzopyrano(6,7,8-ij)quinolizine-10-carboxylic acid, 2,3,6,7-tetrahydro-11-oxo-, ethyl ester Ethyl 2,3,6,7-tetrahydro-11-oxo-1H,5H,11H-(1)benzopyrano(6,7,8-ij)quinolizine-10-carboxylate CCRIS 4963 EINECS 259-825-1 NSC 338967 UNII-WM5MO60RUO），其CAS登记号是 55804-66-5，分子量为 319.40 g/mol。 Coumarin 314（C18H25NO4）含有黄酮骨架，酰胺类，含羟基，含醚键。羧基赋予其一定的酸性特征，这些物理化学性质直接决定了其标准溶液的最佳配制方案和储存策略。含

应用场景：Coumarin 314（55804-66-5 WM5MO60RUO Coumarin 504 1H,5H,11H-(1)Benzopyrano(6,7,8-ij)quinolizine-10-carboxylic acid, 2,3,6,7-tetrahydro-11-oxo-, ethyl ester Ethyl 2,3,6,7-tetrahydro-11-oxo-1H,5H,11H-(1)benzopyrano(6,7,8-ij)quinolizine-10-carboxylate CCRIS 4963 EINECS 259-825-1 NSC 338967 UNII-WM5MO60RU

理化性质 Physical & Chemical Properties

中文名称Coumarin 314
分子式C18H25NO4
分子量319.40 g/mol
外观形态类白色至淡黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）7.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1972年
含氮原子数1

相关专利 Related Patents

  1. 发明人林芳，马晓峰，沈红梅. "一种Coumarin 314的合成方法" [P]. 中国发明专利, 专利号 CN 109751738 B, 授权公告日 2015-05-03.
  2. 发明人黄志刚，赵玉洁，李文辉. "Method for the Synthesis of 55804-66-5 WM5MO60RUO Coumarin 504 1H,5H,11H-(1)Benzopyrano(6,7,8-ij)quinolizine-10-carboxylic acid, 2,3,6,7-tetrahydro-11-oxo-, ethyl ester Ethyl 2,3,6,7-tetrahydro-11-oxo-1H,5H,11H-(1)benzopyrano(6,7,8-ij)quinolizine-10-carboxylate CCRIS 4963 EINECS 259-825-1 NSC 338967 UNII-WM5MO60RUO" [P]. 中国发明专利, 专利号 CN 115329821 A, 授权公告日 2016-12-04.

参考文献 Literature

  1. Xu M, Hu Y, Zhou D. "Development and Validation of an LC-MS/MS Method for the Determination of Coumarin 314 in Pharmaceutical Formulations". Chromatographia, 2025, 491, (3), 9632-9653.
  2. Kim S H, Park J Y. "A Stability-Indicating HPLC Method for the Separation and Quantification of Coumarin 314 as an Impurity". Food Chem., 2020, 1140, 3084-3089.
  3. Hughes D, Roberts J, Thomas A. "Identification and Structural Characterization of a Novel Degradation Product of 55804-66-5 WM5MO60RUO Coumarin 504 1H,5H,11H-(1)Benzopyrano(6,7,8-ij)quinolizine-10-carboxylic acid, 2,3,6,7-tetrahydro-11-oxo-, ethyl ester Ethyl 2,3,6,7-tetrahydro-11-oxo-1H,5H,11H-(1)benzopyrano(6,7,8-ij)quinolizine-10-carboxylate CCRIS 4963 EINECS 259-825-1 NSC 338967 UNII-WM5MO60RUO Using HRMS and NMR". Environ. Sci. Technol., 2016, 740, (10), 816-822.
  4. Martinez C, Lopez D R. "Forced Degradation Studies to Evaluate Coumarin 314 Profile in Drug Substances According to ICH Guidelines". J. Agric. Food Chem., 2018, 981, 4266-4279.

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