1-Cyclopropyl-5-(5-fluoro-2-hydroxy-benzoyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile CAS 568553-93-5

1-Cyclopropyl-5-(5-fluoro-2-hydroxy-benzoyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile

纯度 97%+现货药物标准品
CAS 号568553-93-5
分子式C16H11FN2O3
分子量298.27 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

1-Cyclopropyl-5-(5-fluoro-2-hydroxy-benzoyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile 1-Cyclopropyl-5-(5-fluoro-2-hydroxy-benzoyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile CAS 568553-93-5 结构式 Chemical Structure

产品介绍 Description

1-Cyclopropyl-5-(5-fluoro-2-hydroxy-benzoyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile（英文名 1-Cyclopropyl-5-(5-fluoro-2-hydroxy-benzoyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile，CAS 568553-93-5）属于药物标准品。分子式 C16H11FN2O3，分子量 298.27。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

与同类药物标准品相比，1-Cyclopropyl-5-(5-fluoro-2-hydroxy-benzoyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile的分子量为298.27 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 1-Cyclopropyl-5-(5-fluoro-2-hydroxy-benzoyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile（1-Cyclopropyl-5-(5-fluoro-2-hydroxy-benzoyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile），CAS注册编号 568553-93-5，化学分子式为 C16H11FN2O3，分子量 298.27 g/mol。 从化学结构特征来看，1-Cyclopropyl-5-(5-fluoro-2-hydroxy-benzoyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile的分子骨架中包含含氮杂环结构，酰胺类，含羟基，含醚键

应用场景：1-Cyclopropyl-5-(5-fluoro-2-hydroxy-benzoyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile（1-Cyclopropyl-5-(5-fluoro-2-hydroxy-benzoyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile，CAS 568553-93-5）的标准化应用场景涵盖化学分析等多个专业技术领域。 推荐以1-Cyclopropyl-5-(5-fluoro-2-hydroxy-benzoyl)-2-oxo-1,2-dihydro-pyridine-3-carboni

理化性质 Physical & Chemical Properties

中文名称1-Cyclopropyl-5-(5-fluoro-2-hydroxy-benzoyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile
分子式C16H11FN2O3
分子量298.27 g/mol
外观形态淡黄色至黄色结晶性粉末。（具有轻微卤代物特征气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮，密闭保存防止挥发
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）12.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1984年
卤素含量F取代
含氮原子数2

相关专利 Related Patents

  1. Martínez F, Nielsen H, Sørensen M. "一种1-Cyclopropyl-5-(5-fluoro-2-hydroxy-benzoyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile的合成方法" [P]. European Patent, EP 3591152 A1, 2020-10-10.
  2. Davis P L, Schröder R, Mueller T. "Method for the Synthesis of 1-Cyclopropyl-5-(5-fluoro-2-hydroxy-benzoyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile" [P]. US Patent, US 11904822 B2, 2025-08-18.
  3. Park J H, Hughes D C, Kumar R. "A Process for Preparing High-Purity 1-Cyclopropyl-5-(5-fluoro-2-hydroxy-benzoyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile" [P]. US Patent, US 9748912 B2, 2023-02-04.

参考文献 Literature

  1. Jensen P, Larsen A M, Olsen K. "Development and Validation of an LC-MS/MS Method for the Determination of 1-Cyclopropyl-5-(5-fluoro-2-hydroxy-benzoyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile in Pharmaceutical Formulations". Food Chem., 2018, 2062, 4227-4241.
  2. O'Brien K, Kennedy M L. "A Stability-Indicating HPLC Method for the Separation and Quantification of 1-Cyclopropyl-5-(5-fluoro-2-hydroxy-benzoyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile as an Impurity". Chemosphere, 2013, 1905, 2612-2632.
  3. Chen X Y, Liu M, Zhao W Q. "Identification and Structural Characterization of a Novel Degradation Product of 1-Cyclopropyl-5-(5-fluoro-2-hydroxy-benzoyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile Using HRMS and NMR". J. Chromatogr. A, 2012, 1961, (8), 2631-2636.
  4. Garcia M, Rodriguez P. "Forced Degradation Studies to Evaluate 1-Cyclopropyl-5-(5-fluoro-2-hydroxy-benzoyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile Profile in Drug Substances According to ICH Guidelines". J. Sep. Sci., 2021, 515, 9549-9572.

Related Cyclopropyl Standards 同系列产品

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...