地异喹 硫酸酯 CAS 581-88-4

1,2,3, 4-Tetrahydro-isoquinoline-2-carboxamidine sulfate 2(1H)-Isoquinolinecarboxamidine, 3,4-dihydro-, sulfate (2:1) 2(1H)-Isoquinolinecarboximidamide, 3,4-dihydro-, sulfate (2:1) 3,4-Dihydro-2(1H)-isoquinoline carboxamidine sulfate 3,4-Dihydro-2(1H)-isoquinolinecarboxamidine sulfate (2:1) 3,4-dihydro-1H-isoquinoline-2-carboxamidine 581-88-4 Debrisoquin hemisulfate Debrisoquin sulfate Debrisoquine sulfate Declinax Equitonil Isocaramidine sulfate NSC139330 RO 5-3307/1 Sulfuric acid compound with 3,4-dihydro-2(1H)-isoquinolinecarboximidamide (1:1) Tendor

纯度 97%+现货药物标准品
CAS 号581-88-4
分子式2*C10H19N3 H2O4S
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

地异喹 硫酸酯 1,2,3, 4-Tetrahydro-isoquinoline-2-carboxamidine sulfate 2(1H)-Isoquinolinecarboxamidine, 3,4-dihydro-, sulfate (2:1) 2(1H)-Isoquinolinecarboximidamide, 3,4-dihydro-, sulfate (2:1) 3,4-Dihydro-2(1H)-isoquinoline carboxamidine sulfate 3,4-Dihydro-2(1H)-isoquinolinecarboxamidine sulfate (2:1) 3,4-dihydro-1H-isoquinoline-2-carboxamidine 581-88-4 Debrisoquin hemisulfate Debrisoquin sulfate Debrisoquine sulfate Declinax Equitonil Isocaramidine sulfate NSC139330 RO 5-3307/1 Sulfuric acid compound with 3,4-dihydro-2(1H)-isoquinolinecarboximidamide (1:1) Tendor CAS 581-88-4 结构式 Chemical Structure

产品介绍 Description

地异喹 硫酸酯（英文名 1,2,3, 4-Tetrahydro-isoquinoline-2-carboxamidine sulfate 2(1H)-Isoquinolinecarboxamidine, 3,4-dihydro-, sulfate (2:1) 2(1H)-Isoquinolinecarboximidamide, 3,4-dihydro-, sulfate (2:1) 3,4-Dihydro-2(1H)-isoquinoline carboxamidine sulfate 3,4-Dihydro-2(1H)-isoquinolinecarboxamidine sulfate (2:1) 3,4-dihydro-1H-isoquinoline-2-carboxamidine 581-88-4 Debrisoquin hemisulfate Debrisoquin sulfate Debrisoquine sulfate Declinax Equitonil Isocaramidine sulfate NSC139330 RO 5-3307/1 Sulfuric acid compound with 3,4-dihydro-2(1H)-isoquinolinecarboximidamide (1:1) Tendor，CAS 581-88-4）属于药物标准品。分子式 2*C10H19N3 H2O4S。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括地异喹 硫酸酯在内的目标物的控制。 地异喹 硫酸酯（1,2,3, 4-Tetrahydro-isoquinoline-2-carboxamidine sulfate 2(1H)-Isoquinolinecarboxamidine, 3,4-dihydro-, sulfate (2:1) 2(1H)-Isoquinolinecarboximidamide, 3,4-dihydro-, sulfate (2:1) 3,4-Dihydro-2(1H)-isoquinoline carboxamidine sulfate 3,4-Dihydro-2(1H)-isoquinolinecarboxamidine sulfate (2:1) 3,4-dihydro-1H-isoquinoline-2-carboxamidine 581-88-4 Debrisoquin hemisulfate Debrisoquin sulfate Debrisoquine sulfate Declinax Equitonil Isocaramidine

应用场景：地异喹 硫酸酯（1,2,3, 4-Tetrahydro-isoquinoline-2-carboxamidine sulfate 2(1H)-Isoquinolinecarboxamidine, 3,4-dihydro-, sulfate (2:1) 2(1H)-Isoquinolinecarboximidamide, 3,4-dihydro-, sulfate (2:1) 3,4-Dihydro-2(1H)-isoquinoline carboxamidine sulfate 3,4-Dihydro-2(1H)-isoquinolinecarboxamidine sulfate (2:1)

理化性质 Physical & Chemical Properties

中文名称地异喹 硫酸酯
分子式2*C10H19N3 H2O4S
分子量279.36 g/mol
外观形态白色至类白色结晶性粉末。（具有氨/胺类微弱气味，含硫化合物特征性气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于甲醇、乙醇、DMSO
稳定性对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.0
CAS登记年份（估）1957年
含氮原子数3
含硫原子数1

相关专利 Related Patents

  1. 发明人冯建国，朱建伟，刘建华. "一种地异喹 硫酸酯的合成方法" [P]. 中国发明专利, 专利号 CN 112923502 B, 授权公告日 2024-04-17.
  2. 发明人冯建国，郑宇鹏，李文辉. "Method for the Synthesis of 1,2,3, 4-Tetrahydro-isoquinoline-2-carboxamidine sulfate 2(1H)-Isoquinolinecarboxamidine, 3,4-dihydro-, sulfate (2:1) 2(1H)-Isoquinolinecarboximidamide, 3,4-dihydro-, sulfate (2:1) 3,4-Dihydro-2(1H)-isoquinoline carboxamidine sulfate 3,4-Dihydro-2(1H)-isoquinolinecarboxamidine sulfate (2:1) 3,4-dihydro-1H-isoquinoline-2-carboxamidine 581-88-4 Debrisoquin hemisulfate Debrisoquin sulfate Debrisoquine sulfate Declinax Equitonil Isocaramidine sulfate NSC139330 RO 5-3307/1 Sulfuric acid compound with 3,4-dihydro-2(1H)-isoquinolinecarboximidamide (1:1) Tendor" [P]. 中国发明专利, 专利号 CN 115498250 B, 授权公告日 2019-03-17.
  3. 发明人周伟，陈志强，张德明. "A Process for Preparing High-Purity 1,2,3, 4-Tetrahydro-isoquinoline-2-carboxamidine sulfate 2(1H)-Isoquinolinecarboxamidine, 3,4-dihydro-, sulfate (2:1) 2(1H)-Isoquinolinecarboximidamide, 3,4-dihydro-, sulfate (2:1) 3,4-Dihydro-2(1H)-isoquinoline carboxamidine sulfate 3,4-Dihydro-2(1H)-isoquinolinecarboxamidine sulfate (2:1) 3,4-dihydro-1H-isoquinoline-2-carboxamidine 581-88-4 Debrisoquin hemisulfate Debrisoquin sulfate Debrisoquine sulfate Declinax Equitonil Isocaramidine sulfate NSC139330 RO 5-3307/1 Sulfuric acid compound with 3,4-dihydro-2(1H)-isoquinolinecarboximidamide (1:1) Tendor" [P]. 中国发明专利, 专利号 CN 115168026 B, 授权公告日 2024-02-20.

参考文献 Literature

  1. Kumar A, Sharma P, Patel R S. "Development and Validation of an LC-MS/MS Method for the Determination of 地异喹 硫酸酯 in Pharmaceutical Formulations". Food Chem., 2021, 1985, 330-340.
  2. Zhou X P, Huang L, Wu G. "A Stability-Indicating HPLC Method for the Separation and Quantification of 地异喹 硫酸酯 as an Impurity". Chemosphere, 2020, 752, (3), 660-665.
  3. Garcia M, Rodriguez P. "Identification and Structural Characterization of a Novel Degradation Product of 1,2,3, 4-Tetrahydro-isoquinoline-2-carboxamidine sulfate 2(1H)-Isoquinolinecarboxamidine, 3,4-dihydro-, sulfate (2:1) 2(1H)-Isoquinolinecarboximidamide, 3,4-dihydro-, sulfate (2:1) 3,4-Dihydro-2(1H)-isoquinoline carboxamidine sulfate 3,4-Dihydro-2(1H)-isoquinolinecarboxamidine sulfate (2:1) 3,4-dihydro-1H-isoquinoline-2-carboxamidine 581-88-4 Debrisoquin hemisulfate Debrisoquin sulfate Debrisoquine sulfate Declinax Equitonil Isocaramidine sulfate NSC139330 RO 5-3307/1 Sulfuric acid compound with 3,4-dihydro-2(1H)-isoquinolinecarboximidamide (1:1) Tendor Using HRMS and NMR". Chromatographia, 2018, 84, (5), 6498-6519.

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