三苯基二氯化锑(V) CAS 594-31-0
594-31-0 Antimony, dichlorotriphenyl- Dichlorotriphenylantimony Antimony, triphenyldichloride BRN 4142072 Dichlorid trifenylantimonicny [Czech] Dichlorotriphenylstibine EINECS 209-834-1 NSC 179782 NSC 432 Stibine, triphenyl-, dichloride (6CI) Triphenylantimony dichloride Triphenylstibine dichloride Dichlorid trifenylantimonicny
| CAS 号 | 594-31-0 |
| 分子式 | C18H33Cl2Sb |
| 分子量 | 442.12 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
本产品为药物标准品三苯基二氯化锑(V)（594-31-0 Antimony, dichlorotriphenyl- Dichlorotriphenylantimony Antimony, triphenyldichloride BRN 4142072 Dichlorid trifenylantimonicny [Czech] Dichlorotriphenylstibine EINECS 209-834-1 NSC 179782 NSC 432 Stibine, triphenyl-, dichloride (6CI) Triphenylantimony dichloride Triphenylstibine dichloride Dichlorid trifenylantimonicny，CAS 594-31-0），分子式 C18H33Cl2Sb，分子量 442.12。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。
三苯基二氯化锑(V)的产生途径与其化学式中含氯取代密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 CAS编号 594-31-0 对应的化合物三苯基二氯化锑(V)（英文标识 594-31-0 Antimony, dichlorotriphenyl- Dichlorotriphenylantimony Antimony, triphenyldichloride BRN 4142072 Dichlorid trifenylantimonicny Czech Dichlorotriphenylstibine EINECS 209-834-1 NSC 179782 NSC 432 Stibine, triphenyl-, dichloride (6CI) Triphenylantimony dichloride Triphenylstibine dichloride Dichlorid trifenylantimonicny），化学式 C18H33Cl2Sb，相对分子质量 442.12。 依据分子式为 C18H33Cl2Sb 的三苯基二氯化锑(V)结构特征，其分子
应用场景：三苯基二氯化锑(V)（594-31-0 Antimony, dichlorotriphenyl- Dichlorotriphenylantimony Antimony, triphenyldichloride BRN 4142072 Dichlorid trifenylantimonicny Czech Dichlorotriphenylstibine EINECS 209-834-1 NSC 179782 NSC 432 Stibine, triphenyl-, dichloride (6CI) Triphenylantimony dichloride Triphenylstibine
理化性质 Physical & Chemical Properties
| 中文名称 | 三苯基二氯化锑(V) |
| 分子式 | C18H33Cl2Sb |
| 分子量 | 442.12 g/mol |
| 外观形态 | 白色至类白色结晶性粉末。（具有轻微卤代物特征气味，挥发性较低） |
| 纯度 | 97%+ |
| 储存条件 | 室温保存 |
| 溶解性参考 | 可溶于氯仿、二氯甲烷、乙酸乙酯 |
| 稳定性 | 在推荐条件下性质稳定 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 1.5 |
| CAS登记年份（估） | 1957年 |
| 卤素含量 | Cl取代 |
相关专利 Related Patents
- 发明人郭海燕，张德明，黄志刚. "一种三苯基二氯化锑(V)的合成方法" [P]. 中国发明专利, 专利号 CN 109786185 A, 授权公告日 2016-07-09.
- 发明人王建平，张德明，钱学锋. "Method for the Synthesis of 594-31-0 Antimony, dichlorotriphenyl- Dichlorotriphenylantimony Antimony, triphenyldichloride BRN 4142072 Dichlorid trifenylantimonicny [Czech] Dichlorotriphenylstibine EINECS 209-834-1 NSC 179782 NSC 432 Stibine, triphenyl-, dichloride (6CI) Triphenylantimony dichloride Triphenylstibine dichloride Dichlorid trifenylantimonicny" [P]. 中国发明专利, 专利号 CN 114330103 B, 授权公告日 2025-12-28.
- 发明人陈志强，张德明，何建平. "A Process for Preparing High-Purity 594-31-0 Antimony, dichlorotriphenyl- Dichlorotriphenylantimony Antimony, triphenyldichloride BRN 4142072 Dichlorid trifenylantimonicny [Czech] Dichlorotriphenylstibine EINECS 209-834-1 NSC 179782 NSC 432 Stibine, triphenyl-, dichloride (6CI) Triphenylantimony dichloride Triphenylstibine dichloride Dichlorid trifenylantimonicny" [P]. 中国发明专利, 专利号 CN 116583600 A, 授权公告日 2022-11-13.
参考文献 Literature
- O'Brien K, Kennedy M L. "Development and Validation of an LC-MS/MS Method for the Determination of 三苯基二氯化锑(V) in Pharmaceutical Formulations". Chemosphere, 2023, 2411, 4525-4550.
- Yamamoto K, Tanaka H, Suzuki T. "A Stability-Indicating HPLC Method for the Separation and Quantification of 三苯基二氯化锑(V) as an Impurity". Chromatographia, 2017, 249, 2106-2125.
- Smith J A, Johnson M B. "Identification and Structural Characterization of a Novel Degradation Product of 594-31-0 Antimony, dichlorotriphenyl- Dichlorotriphenylantimony Antimony, triphenyldichloride BRN 4142072 Dichlorid trifenylantimonicny [Czech] Dichlorotriphenylstibine EINECS 209-834-1 NSC 179782 NSC 432 Stibine, triphenyl-, dichloride (6CI) Triphenylantimony dichloride Triphenylstibine dichloride Dichlorid trifenylantimonicny Using HRMS and NMR". Biomed. Chromatogr., 2012, 1311, 5573-5581.
- Garcia M, Rodriguez P. "Forced Degradation Studies to Evaluate 三苯基二氯化锑(V) Profile in Drug Substances According to ICH Guidelines". Sci. Total Environ., 2016, 549, (1), 4014-4040.
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