(2-Hydroxyphenyl)(4-hydroxyphenyl)methanone CAS 606-12-2

2,4'-Dihydroxybenzophenone 606-12-2 Benzophenone,4'-dihydroxy- Methanone, (2-hydroxyphenyl)(4-hydroxyphenyl)- NSC-2832 NSC2832

纯度 97%+现货药物标准品
CAS 号606-12-2
分子式C13H22O3
分子量226.31 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(2-Hydroxyphenyl)(4-hydroxyphenyl)methanone 2,4'-Dihydroxybenzophenone 606-12-2 Benzophenone,4'-dihydroxy- Methanone, (2-hydroxyphenyl)(4-hydroxyphenyl)- NSC-2832 NSC2832 CAS 606-12-2 结构式 Chemical Structure

产品介绍 Description

(2-Hydroxyphenyl)(4-hydroxyphenyl)methanone（英文名 2,4'-Dihydroxybenzophenone 606-12-2 Benzophenone,4'-dihydroxy- Methanone, (2-hydroxyphenyl)(4-hydroxyphenyl)- NSC-2832 NSC2832，CAS 606-12-2）属于药物标准品。分子式 C13H22O3，分子量 226.31。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

(2-Hydroxyphenyl)(4-hydroxyphenyl)methanone的产生途径与其化学式中羧酸类，含羟基，含醚键密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 化学式为 C13H22O3 的(2-Hydroxyphenyl)(4-hydroxyphenyl)methanone（2,4'-Dihydroxybenzophenone 606-12-2 Benzophenone,4'-dihydroxy- Methanone, (2-hydroxyphenyl)(4-hydroxyphenyl)- NSC-2832 NSC2832），其CAS登记号是 606-12-2，分子量为 226.31 g/mol。 从化学结构特征来看，(2-Hydroxyphenyl)(4-hydroxyphenyl)methanone的分子骨架中包含羧酸类，含羟基，含醚键。该化合物的不饱和度为3.0，表明结构中存在约3个环或双键等价单元。分子量为226.31 g/mol，属于中等分子量化合物。由于碳链较长，脂溶性良好，该化合物在Octanol-Water分配系数测试中倾

应用场景：(2-Hydroxyphenyl)(4-hydroxyphenyl)methanone（2,4'-Dihydroxybenzophenone 606-12-2 Benzophenone,4'-dihydroxy- Methanone, (2-hydroxyphenyl)(4-hydroxyphenyl)- NSC-2832 NSC2832）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐以(2-Hydroxyphenyl)(4-hydroxyphenyl)methanone配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用乙腈为溶剂配制储备溶液，根据检测灵敏度需求逐级

理化性质 Physical & Chemical Properties

中文名称(2-Hydroxyphenyl)(4-hydroxyphenyl)methanone
分子式C13H22O3
分子量226.31 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件阴凉处（≤25°C）保存，密封防潮
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO
稳定性空气中长期暴露可能发生缓慢氧化；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.0
UV特征有紫外吸收
CAS登记年份（估）1957年

相关专利 Related Patents

  1. Roberts E F, Stevens L M, Patel M V. "一种(2-Hydroxyphenyl)(4-hydroxyphenyl)methanone的合成方法" [P]. US Patent, US 10991053 B2, 2021-04-25.
  2. 发明人孙丽萍，刘建华，黄志刚. "Method for the Synthesis of 2,4'-Dihydroxybenzophenone 606-12-2 Benzophenone,4'-dihydroxy- Methanone, (2-hydroxyphenyl)(4-hydroxyphenyl)- NSC-2832 NSC2832" [P]. 中国发明专利, 专利号 CN 111553805 A, 授权公告日 2021-12-04.

参考文献 Literature

  1. Martinez C, Lopez D R. "Development and Validation of an LC-MS/MS Method for the Determination of (2-Hydroxyphenyl)(4-hydroxyphenyl)methanone in Pharmaceutical Formulations". Chemosphere, 2024, 1525, 1417-1447.
  2. Yamamoto K, Tanaka H, Suzuki T. "A Stability-Indicating HPLC Method for the Separation and Quantification of (2-Hydroxyphenyl)(4-hydroxyphenyl)methanone as an Impurity". J. Nat. Prod., 2017, 899, 6050-6078.
  3. Mueller T, Schmidt R K. "Identification and Structural Characterization of a Novel Degradation Product of 2,4'-Dihydroxybenzophenone 606-12-2 Benzophenone,4'-dihydroxy- Methanone, (2-hydroxyphenyl)(4-hydroxyphenyl)- NSC-2832 NSC2832 Using HRMS and NMR". Molecules, 2019, 1780, (7), 6203-6212.
  4. Xu M, Hu Y, Zhou D. "Forced Degradation Studies to Evaluate (2-Hydroxyphenyl)(4-hydroxyphenyl)methanone Profile in Drug Substances According to ICH Guidelines". J. Chromatogr. A, 2014, 604, (3), 9821-9835.

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