反应红120 CAS 61951-82-4

2,7-Naphthalenedisulfonic acid, 4,4'-[1,4-phenylenebis[imino(6-chloro-1,3,5-triazine-4,2-diyl)imino]]bis[5-hydroxy-6-[(2-sulfophenyl)azo]- 5-[[4-chloro-6-[4-[[4-chloro-6-[[8-hydroxy-3,6-disulfo-7-[(E)-(2-sulfophenyl)azo]-1-naphthyl]amino]-1,3,5-triazin-2-yl]amino]anilino]-1,3,5-triazin-2-yl]amino]-4-hydroxy-3-[(E)-(2-sulfophenyl)azo]naphthalene-2,7-disulfonic acid 61951-82-4 Reactive Red 120

纯度 97%+现货药物标准品
CAS 号61951-82-4
分子式C44H80Cl2N14O20S6
分子量1388.48 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

反应红120 2,7-Naphthalenedisulfonic acid, 4,4'-[1,4-phenylenebis[imino(6-chloro-1,3,5-triazine-4,2-diyl)imino]]bis[5-hydroxy-6-[(2-sulfophenyl)azo]- 5-[[4-chloro-6-[4-[[4-chloro-6-[[8-hydroxy-3,6-disulfo-7-[(E)-(2-sulfophenyl)azo]-1-naphthyl]amino]-1,3,5-triazin-2-yl]amino]anilino]-1,3,5-triazin-2-yl]amino]-4-hydroxy-3-[(E)-(2-sulfophenyl)azo]naphthalene-2,7-disulfonic acid 61951-82-4 Reactive Red 120 CAS 61951-82-4 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品反应红120（2,7-Naphthalenedisulfonic acid, 4,4'-[1,4-phenylenebis[imino(6-chloro-1,3,5-triazine-4,2-diyl)imino]]bis[5-hydroxy-6-[(2-sulfophenyl)azo]- 5-[[4-chloro-6-[4-[[4-chloro-6-[[8-hydroxy-3,6-disulfo-7-[(E)-(2-sulfophenyl)azo]-1-naphthyl]amino]-1,3,5-triazin-2-yl]amino]anilino]-1,3,5-triazin-2-yl]amino]-4-hydroxy-3-[(E)-(2-sulfophenyl)azo]naphthalene-2,7-disulfonic acid 61951-82-4 Reactive Red 120，CAS 61951-82-4），分子式 C44H80Cl2N14O20S6，分子量 1388.48。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

本品适用于HPLC、GC、LC-MS/MS、GC-MS等主要色谱平台的定量分析，可作为外标法校准标准品或系统适用性测试参考物质使用。 化学式为 C44H80Cl2N14O20S6 的反应红120（2,7-Naphthalenedisulfonic acid, 4,4'-1,4-phenylenebisimino(6-chloro-1,3,5-triazine-4,2-diyl)iminobis5-hydroxy-6-(2-sulfophenyl)azo- 5-4-chloro-6-4-4-chloro-6-8-hydroxy-3,6-disulfo-7-(E)-(2-sulfophenyl)azo-1-naphthylamino-1,3,5-triazin-2-ylaminoanilino-1,3,5-triazin-2-ylamino-4-hydroxy-3-(E)-(2-sulfophenyl)azonaphthalene-2,7-disulfonic acid 61951-82-4 Reactive Re

应用场景：反应红120（2,7-Naphthalenedisulfonic acid, 4,4'- 1,4-phenylenebis imino(6-chloro-1,3,5-triazine-4,2-diyl)imino bis 5-hydroxy-6- (2-sulfophenyl)azo - 5- 4-chloro-6- 4- 4-chloro-6- 8-hydroxy-3,6-disulfo-7- (E)-(2-sulfophenyl)azo -1-naphthyl amino -1,3,5-triazin-2-yl amino anilino -1,3,5-triazin-2-yl a

理化性质 Physical & Chemical Properties

中文名称反应红120
分子式C44H80Cl2N14O20S6
分子量1388.48 g/mol
外观形态淡黄色至黄色无定形粉末。（具有轻微卤代物特征气味，含硫化合物特征性气味，挥发性较低）
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）11.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1974年
卤素含量Cl取代
含氮原子数14
含硫原子数6

相关专利 Related Patents

  1. 发明人刘建华，郭海燕，李文辉. "一种反应红120的合成方法" [P]. 中国发明专利, 专利号 CN 108473435 A, 授权公告日 2022-11-22.
  2. 发明人韩伟，朱建伟，钱学锋. "Method for the Synthesis of 2,7-Naphthalenedisulfonic acid, 4,4'-[1,4-phenylenebis[imino(6-chloro-1,3,5-triazine-4,2-diyl)imino]]bis[5-hydroxy-6-[(2-sulfophenyl)azo]- 5-[[4-chloro-6-[4-[[4-chloro-6-[[8-hydroxy-3,6-disulfo-7-[(E)-(2-sulfophenyl)azo]-1-naphthyl]amino]-1,3,5-triazin-2-yl]amino]anilino]-1,3,5-triazin-2-yl]amino]-4-hydroxy-3-[(E)-(2-sulfophenyl)azo]naphthalene-2,7-disulfonic acid 61951-82-4 Reactive Red 120" [P]. 中国发明专利, 专利号 CN 116121364 B, 授权公告日 2018-03-14.
  3. 发明人钱学锋，高志强，沈红梅. "A Process for Preparing High-Purity 2,7-Naphthalenedisulfonic acid, 4,4'-[1,4-phenylenebis[imino(6-chloro-1,3,5-triazine-4,2-diyl)imino]]bis[5-hydroxy-6-[(2-sulfophenyl)azo]- 5-[[4-chloro-6-[4-[[4-chloro-6-[[8-hydroxy-3,6-disulfo-7-[(E)-(2-sulfophenyl)azo]-1-naphthyl]amino]-1,3,5-triazin-2-yl]amino]anilino]-1,3,5-triazin-2-yl]amino]-4-hydroxy-3-[(E)-(2-sulfophenyl)azo]naphthalene-2,7-disulfonic acid 61951-82-4 Reactive Red 120" [P]. 中国发明专利, 专利号 CN 114453626 A, 授权公告日 2019-09-27.

参考文献 Literature

  1. Mueller T, Schmidt R K. "Development and Validation of an LC-MS/MS Method for the Determination of 反应红120 in Pharmaceutical Formulations". Rapid Commun. Mass Spectrom., 2020, 1197, 6742-6756.
  2. Mueller T, Schmidt R K. "A Stability-Indicating HPLC Method for the Separation and Quantification of 反应红120 as an Impurity". J. Pharm. Biomed. Anal., 2020, 2252, (1), 8451-8477.
  3. Chen X Y, Liu M, Zhao W Q. "Identification and Structural Characterization of a Novel Degradation Product of 2,7-Naphthalenedisulfonic acid, 4,4'-[1,4-phenylenebis[imino(6-chloro-1,3,5-triazine-4,2-diyl)imino]]bis[5-hydroxy-6-[(2-sulfophenyl)azo]- 5-[[4-chloro-6-[4-[[4-chloro-6-[[8-hydroxy-3,6-disulfo-7-[(E)-(2-sulfophenyl)azo]-1-naphthyl]amino]-1,3,5-triazin-2-yl]amino]anilino]-1,3,5-triazin-2-yl]amino]-4-hydroxy-3-[(E)-(2-sulfophenyl)azo]naphthalene-2,7-disulfonic acid 61951-82-4 Reactive Red 120 Using HRMS and NMR". Chromatographia, 2025, 1691, 5237-5267.
  4. Lee J H, Choi Y S. "Forced Degradation Studies to Evaluate 反应红120 Profile in Drug Substances According to ICH Guidelines". Food Chem., 2023, 2210, (12), 9005-9018.

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