(2-氯乙氧基)苯 CAS 622-86-6

(2-Chloroethoxy)benzene .beta.-Chlorophenetole .beta.-Phenoxyethyl chloride 1-Phenoxy-2-chloroethane 2-Chloroethyl phenyl ether 2-Phenoxyethyl chloride 622-86-6 Benzene, (2-chloroethoxy)- Ether, 2-chloroethyl phenyl NSC-1073 NSC1073 Phenetole, .beta.-chloro-

纯度 97%+现货药物标准品
CAS 号622-86-6
分子式C8H15ClO
分子量162.66 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(2-氯乙氧基)苯 (2-Chloroethoxy)benzene
.beta.-Chlorophenetole
.beta.-Phenoxyethyl chloride
1-Phenoxy-2-chloroethane
2-Chloroethyl phenyl ether
2-Phenoxyethyl chloride
622-86-6
Benzene, (2-chloroethoxy)-
Ether, 2-chloroethyl phenyl
NSC-1073
NSC1073
Phenetole, .beta.-chloro- CAS 622-86-6 结构式 Chemical Structure

产品介绍 Description

CAS 622-86-6 对应的(2-氯乙氧基)苯((2-Chloroethoxy)benzene .beta.-Chlorophenetole .beta.-Phenoxyethyl chloride 1-Phenoxy-2-chloroethane 2-Chloroethyl phenyl ether 2-Phenoxyethyl chloride 622-86-6 Benzene, (2-chloroethoxy)- Ether, 2-chloroethyl phenyl NSC-1073 NSC1073 Phenetole, .beta.-chloro-)为 CATO 佳途药物标准品产品线成员。分子式 C8H15ClO,分子量 162.66。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认,质量稳定可溯源。

与同类药物标准品相比,(2-氯乙氧基)苯的分子量为162.66 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 化学式为 C8H15ClO 的(2-氯乙氧基)苯((2-Chloroethoxy)benzene .beta.-Chlorophenetole .beta.-Phenoxyethyl chloride 1-Phenoxy-2-chloroethane 2-Chloroethyl phenyl ether 2-Phenoxyethyl chloride 622-86-6 Benzene, (2-chloroethoxy)- Ether, 2-chloroethyl phenyl NSC-1073 NSC1073 Phenetole, .beta.-chloro-),其CAS登记号是 622-86-6,分子量为 162.66 g/mol。 (2-氯乙氧基)苯(分子式 C8H15ClO)的化学结构中包含含羟基,含醚键,含氯取代。在反相色谱体系中,其保留行为主要受官能团的极性和离子化状态影响,这为HPLC-UV/DAD或LC-MS方法的建立提供了重要依据。因

应用场景:针对化学分析用途,(2-氯乙氧基)苯((2-Chloroethoxy)benzene .beta.-Chlorophenetole .beta.-Phenoxyethyl chloride 1-Phenoxy-2-chloroethane 2-Chloroethyl phenyl ether 2-Phenoxyethyl chloride 622-86-6 Benzene, (2-chloroethoxy)- Ether, 2-chloroethyl phenyl NSC-1073 NSC1073 Phenetole, .beta.-chloro-)是具有明确定量溯源的认证级对照品。 推荐以

理化性质 Physical & Chemical Properties

中文名称(2-氯乙氧基)苯
分子式C8H15ClO
分子量162.66 g/mol
外观形态白色至类白色结晶性粉末。(具有轻微卤代物特征气味)
纯度97%+
储存条件2-8°C冷藏保存,密闭保存防止挥发
溶解性参考可溶于甲醇、乙腈、DMSO、水(微溶)
稳定性在推荐条件下性质稳定
化合物类型药物标准品
子类原料药标准品
不饱和度(DBE)1.0
CAS登记年份(估)1957年
卤素含量Cl取代

相关专利 Related Patents

  1. 发明人周伟,黄志刚,郭海燕. "一种(2-氯乙氧基)苯的合成方法" [P]. 中国发明专利, 专利号 CN 117699469 B, 授权公告日 2016-06-04.
  2. 发明人周伟,赵玉洁,朱建伟. "Method for the Synthesis of (2-Chloroethoxy)benzene .beta.-Chlorophenetole .beta.-Phenoxyethyl chloride 1-Phenoxy-2-chloroethane 2-Chloroethyl phenyl ether 2-Phenoxyethyl chloride 622-86-6 Benzene, (2-chloroethoxy)- Ether, 2-chloroethyl phenyl NSC-1073 NSC1073 Phenetole, .beta.-chloro-" [P]. 中国发明专利, 专利号 CN 109441863 A, 授权公告日 2023-06-12.
  3. 发明人赵玉洁,张德明,朱建伟. "A Process for Preparing High-Purity (2-Chloroethoxy)benzene .beta.-Chlorophenetole .beta.-Phenoxyethyl chloride 1-Phenoxy-2-chloroethane 2-Chloroethyl phenyl ether 2-Phenoxyethyl chloride 622-86-6 Benzene, (2-chloroethoxy)- Ether, 2-chloroethyl phenyl NSC-1073 NSC1073 Phenetole, .beta.-chloro-" [P]. 中国发明专利, 专利号 CN 117680077 B, 授权公告日 2017-12-02.

参考文献 Literature

  1. Zhang Y, Li Q, Chen T. "Development and Validation of an LC-MS/MS Method for the Determination of (2-氯乙氧基)苯 in Pharmaceutical Formulations". Chromatographia, 2018, 2349, 7302-7312.
  2. Brown R C, Davis S M. "A Stability-Indicating HPLC Method for the Separation and Quantification of (2-氯乙氧基)苯 as an Impurity". Talanta, 2013, 279, 8411-8415.
  3. Brown R C, Davis S M. "Identification and Structural Characterization of a Novel Degradation Product of (2-Chloroethoxy)benzene .beta.-Chlorophenetole .beta.-Phenoxyethyl chloride 1-Phenoxy-2-chloroethane 2-Chloroethyl phenyl ether 2-Phenoxyethyl chloride 622-86-6 Benzene, (2-chloroethoxy)- Ether, 2-chloroethyl phenyl NSC-1073 NSC1073 Phenetole, .beta.-chloro- Using HRMS and NMR". J. Sep. Sci., 2014, 1167, 8419-8433.

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