ethylene glycol distearate CAS 627-83-8
13W7MDN21W 627-83-8 Ethylene glycol distearate Glycol distearate Octadecanoic acid, 1,2-ethanediyl ester Glycol distearate [USAN] Ethylene distearate Stearic acid, ethylene ester (8CI) Octadecanoic acid, 1,1'-(1,2-ethanediyl) ester EINECS 211-014-3 Elfan L 310 Emerest 2355 1,2-Ethanediyl bis(octadecanoate) Ethylene glycol dioctadecanoate Ethylene glycol, distearate Ethylene stearate NSC 6820 Stearic acid, ethylene ester UNII-13W7MDN21W EC 211-014-3
| CAS 号 | 627-83-8 |
| 分子式 | C38H74O4 |
| 分子量 | 594.99 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
本产品为药物标准品ethylene glycol distearate（13W7MDN21W 627-83-8 Ethylene glycol distearate Glycol distearate Octadecanoic acid, 1,2-ethanediyl ester Glycol distearate [USAN] Ethylene distearate Stearic acid, ethylene ester (8CI) Octadecanoic acid, 1,1'-(1,2-ethanediyl) ester EINECS 211-014-3 Elfan L 310 Emerest 2355 1,2-Ethanediyl bis(octadecanoate) Ethylene glycol dioctadecanoate Ethylene glycol, distearate Ethylene stearate NSC 6820 Stearic acid, ethylene ester UNII-13W7MDN21W EC 211-014-3，CAS 627-83-8），分子式 C38H74O4，分子量 594.99。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。
ethylene glycol distearate的产生途径与其化学式中羧酸类，含羟基，含醚键密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 ethylene glycol distearate（13W7MDN21W 627-83-8 Ethylene glycol distearate Glycol distearate Octadecanoic acid, 1,2-ethanediyl ester Glycol distearate USAN Ethylene distearate Stearic acid, ethylene ester (8CI) Octadecanoic acid, 1,1'-(1,2-ethanediyl) ester EINECS 211-014-3 Elfan L 310 Emerest 2355 1,2-Ethanediyl bis(octadecanoate) Ethylene glycol dioctadecanoate Ethylene glycol, distearate Ethylene stearate NS
应用场景：从实际应用出发，ethylene glycol distearate（CAS 627-83-8）在化学分析中作为关键的基准对照物质。 推荐以ethylene glycol distearate配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用乙腈为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用乙腈配制，于室温保存，密封防潮条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用，防止吸潮影响称量准确性。
理化性质 Physical & Chemical Properties
| 中文名称 | ethylene glycol distearate |
| 分子式 | C38H74O4 |
| 分子量 | 594.99 g/mol |
| 外观形态 | 白色至类白色结晶性粉末 |
| 纯度 | 97%+ |
| 储存条件 | 室温保存，密封防潮 |
| 溶解性参考 | 可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO |
| 稳定性 | 在推荐条件下性质稳定 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 2.0 |
| CAS登记年份（估） | 1957年 |
相关专利 Related Patents
- Johnson M A, Hughes D C, Davis P L. "一种ethylene glycol distearate的合成方法" [P]. US Patent, US 9705402 B2, 2021-11-21.
- 发明人黄志刚，李文辉，赵玉洁. "Method for the Synthesis of 13W7MDN21W 627-83-8 Ethylene glycol distearate Glycol distearate Octadecanoic acid, 1,2-ethanediyl ester Glycol distearate [USAN] Ethylene distearate Stearic acid, ethylene ester (8CI) Octadecanoic acid, 1,1'-(1,2-ethanediyl) ester EINECS 211-014-3 Elfan L 310 Emerest 2355 1,2-Ethanediyl bis(octadecanoate) Ethylene glycol dioctadecanoate Ethylene glycol, distearate Ethylene stearate NSC 6820 Stearic acid, ethylene ester UNII-13W7MDN21W EC 211-014-3" [P]. 中国发明专利, 专利号 CN 116884570 A, 授权公告日 2016-05-03.
参考文献 Literature
- Smith J A, Johnson M B. "Development and Validation of an LC-MS/MS Method for the Determination of ethylene glycol distearate in Pharmaceutical Formulations". Anal. Chim. Acta, 2014, 136, (11), 2459-2476.
- Brown R C, Davis S M. "A Stability-Indicating HPLC Method for the Separation and Quantification of ethylene glycol distearate as an Impurity". J. Agric. Food Chem., 2020, 2102, (12), 9601-9624.
- Jensen P, Larsen A M, Olsen K. "Identification and Structural Characterization of a Novel Degradation Product of 13W7MDN21W 627-83-8 Ethylene glycol distearate Glycol distearate Octadecanoic acid, 1,2-ethanediyl ester Glycol distearate [USAN] Ethylene distearate Stearic acid, ethylene ester (8CI) Octadecanoic acid, 1,1'-(1,2-ethanediyl) ester EINECS 211-014-3 Elfan L 310 Emerest 2355 1,2-Ethanediyl bis(octadecanoate) Ethylene glycol dioctadecanoate Ethylene glycol, distearate Ethylene stearate NSC 6820 Stearic acid, ethylene ester UNII-13W7MDN21W EC 211-014-3 Using HRMS and NMR". Anal. Chem., 2025, 388, 8252-8272.
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