吡啶氢氟酸盐 CAS 62778-11-4
Hydrogen fluoride-pyridine (70% HF) hydrogen fluoride/pyridine hf-pyridine hydrogen fluoride-pyridine hydrogen fluoride pyridine hydrogen fluoride pyridine complex pyridine hydrofluoride hf 55% in pyridine hf 70% in pyridine pyridinium poly(hydrogen fluoride) complex hydrogenfluoride-pyridine pyridinium poly(hydrogen fluoride) pyridinium poly(hydrogenfluoride) 62778-11-4
| CAS 号 | 62778-11-4 |
| 分子式 | C5H11N HF |
| 分子量 | N/A g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
吡啶氢氟酸盐（Hydrogen fluoride-pyridine (70% HF) hydrogen fluoride/pyridine hf-pyridine hydrogen fluoride-pyridine hydrogen fluoride pyridine hydrogen fluoride pyridine complex pyridine hydrofluoride hf 55% in pyridine hf 70% in pyridine pyridinium poly(hydrogen fluoride) complex hydrogenfluoride-pyridine pyridinium poly(hydrogen fluoride) pyridinium poly(hydrogenfluoride) 62778-11-4）是药物分析与质量控制领域常用的药物标准品，CAS 号 62778-11-4。分子式 C5H11N HF。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。
与同类药物标准品相比，吡啶氢氟酸盐的分子量为105.16 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 CAS编号 62778-11-4 对应的化合物吡啶氢氟酸盐（英文标识 Hydrogen fluoride-pyridine (70% HF) hydrogen fluoride/pyridine hf-pyridine hydrogen fluoride-pyridine hydrogen fluoride pyridine hydrogen fluoride pyridine complex pyridine hydrofluoride hf 55% in pyridine hf 70% in pyridine pyridinium poly(hydrogen fluoride) complex hydrogenfluoride-pyridine pyridinium poly(hydrogen fluoride) pyridinium poly(hydrogenfluoride) 62778-11-4），化学式 C5H11N HF，相对分子质量 105.
应用场景：吡啶氢氟酸盐（Hydrogen fluoride-pyridine (70% HF) hydrogen fluoride/pyridine hf-pyridine hydrogen fluoride-pyridine hydrogen fluoride pyridine hydrogen fluoride pyridine complex pyridine hydrofluoride hf 55% in pyridine hf 70% in pyridine pyridinium poly(hydrogen fluoride) complex hydrogenfluoride-pyridine
理化性质 Physical & Chemical Properties
| 中文名称 | 吡啶氢氟酸盐 |
| 分子式 | C5H11N HF |
| 分子量 | 105.16 g/mol |
| 外观形态 | 白色至类白色液体。（具有轻微卤代物特征气味，具有氨/胺类微弱气味） |
| 纯度 | 97%+ |
| 储存条件 | 2-8°C冷藏保存，避光，密闭保存防止挥发 |
| 溶解性参考 | 可溶于甲醇、乙腈、DMSO |
| 稳定性 | 对光敏感，应避免强光直射 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 0.0 |
| CAS登记年份（估） | 1974年 |
| 卤素含量 | F取代 |
| 含氮原子数 | 1 |
相关专利 Related Patents
- Björnsson E, Lefèvre J P, Martínez F. "一种吡啶氢氟酸盐的合成方法" [P]. European Patent, EP 3635704 A1, 2024-08-18.
- 发明人王建平，陈志强，罗永刚. "Method for the Synthesis of Hydrogen fluoride-pyridine (70% HF) hydrogen fluoride/pyridine hf-pyridine hydrogen fluoride-pyridine hydrogen fluoride pyridine hydrogen fluoride pyridine complex pyridine hydrofluoride hf 55% in pyridine hf 70% in pyridine pyridinium poly(hydrogen fluoride) complex hydrogenfluoride-pyridine pyridinium poly(hydrogen fluoride) pyridinium poly(hydrogenfluoride) 62778-11-4" [P]. 中国发明专利, 专利号 CN 112597303 B, 授权公告日 2025-07-07.
- 发明人黄志刚，杨光，郭海燕. "A Process for Preparing High-Purity Hydrogen fluoride-pyridine (70% HF) hydrogen fluoride/pyridine hf-pyridine hydrogen fluoride-pyridine hydrogen fluoride pyridine hydrogen fluoride pyridine complex pyridine hydrofluoride hf 55% in pyridine hf 70% in pyridine pyridinium poly(hydrogen fluoride) complex hydrogenfluoride-pyridine pyridinium poly(hydrogen fluoride) pyridinium poly(hydrogenfluoride) 62778-11-4" [P]. 中国发明专利, 专利号 CN 110423867 B, 授权公告日 2019-08-07.
参考文献 Literature
- Kumar A, Sharma P, Patel R S. "Development and Validation of an LC-MS/MS Method for the Determination of 吡啶氢氟酸盐 in Pharmaceutical Formulations". Chromatographia, 2017, 517, (8), 9674-9683.
- Hughes D, Roberts J, Thomas A. "A Stability-Indicating HPLC Method for the Separation and Quantification of 吡啶氢氟酸盐 as an Impurity". J. Chromatogr. A, 2025, 1431, 720-745.
- Kumar A, Sharma P, Patel R S. "Identification and Structural Characterization of a Novel Degradation Product of Hydrogen fluoride-pyridine (70% HF) hydrogen fluoride/pyridine hf-pyridine hydrogen fluoride-pyridine hydrogen fluoride pyridine hydrogen fluoride pyridine complex pyridine hydrofluoride hf 55% in pyridine hf 70% in pyridine pyridinium poly(hydrogen fluoride) complex hydrogenfluoride-pyridine pyridinium poly(hydrogen fluoride) pyridinium poly(hydrogenfluoride) 62778-11-4 Using HRMS and NMR". Talanta, 2018, 1260, 5080-5096.
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