5-（碘乙酰胺基）荧光素 CAS 63368-54-7

5-(Iodoacetamido)fluorescein 5-IAF 5-Iodoacetamidofluorescein 63368-54-7 Acetamide, N-(3',6'-dihydroxy-3- oxospiro(isobenzofuran-1(3H),9'-(9H) xanthen)-5-yl)-2-iodo- Acetamide, N-(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)-2-iodo- (9CI) Fluorescein iodoacetamide Spiro[isobenzofuran-1(3H),9'-[9H]xanthene], acetamide deriv. acetamide, N-(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)-2-iodo-

纯度 97%+现货药物标准品
CAS 号63368-54-7
分子式C22H32INO6
分子量533.40 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

5-（碘乙酰胺基）荧光素 5-(Iodoacetamido)fluorescein 5-IAF 5-Iodoacetamidofluorescein 63368-54-7 Acetamide, N-(3',6'-dihydroxy-3- oxospiro(isobenzofuran-1(3H),9'-(9H) xanthen)-5-yl)-2-iodo- Acetamide, N-(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)-2-iodo- (9CI) Fluorescein iodoacetamide Spiro[isobenzofuran-1(3H),9'-[9H]xanthene], acetamide deriv. acetamide, N-(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)-2-iodo- CAS 63368-54-7 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品5-（碘乙酰胺基）荧光素（5-(Iodoacetamido)fluorescein 5-IAF 5-Iodoacetamidofluorescein 63368-54-7 Acetamide, N-(3',6'-dihydroxy-3- oxospiro(isobenzofuran-1(3H),9'-(9H) xanthen)-5-yl)-2-iodo- Acetamide, N-(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)-2-iodo- (9CI) Fluorescein iodoacetamide Spiro[isobenzofuran-1(3H),9'-[9H]xanthene], acetamide deriv. acetamide, N-(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)-2-iodo-，CAS 63368-54-7），分子式 C22H32INO6，分子量 533.40。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

化学式为 C22H32INO6 的5-（碘乙酰胺基）荧光素（5-(Iodoacetamido)fluorescein 5-IAF 5-Iodoacetamidofluorescein 63368-54-7 Acetamide, N-(3',6'-dihydroxy-3- oxospiro(isobenzofuran-1(3H),9'-(9H) xanthen)-5-yl)-2-iodo- Acetamide, N-(3',6'-dihydroxy-3-oxospiroisobenzofuran-1(3H),9'-9Hxanthen-5-yl)-2-iodo- (9CI) Fluorescein iodoacetamide Spiroisobenzofuran-1(3H),9'-9Hxanthene, acetamide deriv. acetamide, N-(3',6'-dihydroxy-3-oxospiroisobenzofuran-1(3H),9'-9Hxanthen-5-yl)-2-iodo-），其CAS登记号是 63368-54-7，分子量为 533

应用场景：5-（碘乙酰胺基）荧光素（5-(Iodoacetamido)fluorescein 5-IAF 5-Iodoacetamidofluorescein 63368-54-7 Acetamide, N-(3',6'-dihydroxy-3- oxospiro(isobenzofuran-1(3H),9'-(9H) xanthen)-5-yl)-2-iodo- Acetamide, N-(3',6'-dihydroxy-3-oxospiro isobenzofuran-1(3H),9'- 9H xanthen -5-yl)-2-iodo- (9CI) Fluorescein iodoacetamid

理化性质 Physical & Chemical Properties

中文名称5-（碘乙酰胺基）荧光素
分子式C22H32INO6
分子量533.40 g/mol
外观形态类白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味）
纯度97%+
储存条件室温保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）7.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1975年
卤素含量I取代
含氮原子数1

相关专利 Related Patents

  1. Johnson M A, Park J H, Schröder R. "一种5-（碘乙酰胺基）荧光素的合成方法" [P]. US Patent, US 11366819 B2, 2017-01-24.
  2. 发明人朱建伟，何建平，马晓峰. "Method for the Synthesis of 5-(Iodoacetamido)fluorescein 5-IAF 5-Iodoacetamidofluorescein 63368-54-7 Acetamide, N-(3',6'-dihydroxy-3- oxospiro(isobenzofuran-1(3H),9'-(9H) xanthen)-5-yl)-2-iodo- Acetamide, N-(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)-2-iodo- (9CI) Fluorescein iodoacetamide Spiro[isobenzofuran-1(3H),9'-[9H]xanthene], acetamide deriv. acetamide, N-(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)-2-iodo-" [P]. 中国发明专利, 专利号 CN 116596062 A, 授权公告日 2022-05-24.

参考文献 Literature

  1. Kumar A, Sharma P, Patel R S. "Development and Validation of an LC-MS/MS Method for the Determination of 5-（碘乙酰胺基）荧光素 in Pharmaceutical Formulations". Anal. Chim. Acta, 2016, 2212, (3), 5512-5537.
  2. Kumar A, Sharma P, Patel R S. "A Stability-Indicating HPLC Method for the Separation and Quantification of 5-（碘乙酰胺基）荧光素 as an Impurity". J. Chromatogr. A, 2022, 1832, (1), 6505-6519.

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