Ethyl eosin CAS 6359-05-3

6359-05-3 Benzoic acid, 2- (2,4,5, 7-tetrabromo-6-hydroxy-3-oxo-3H-xanthen-9-yl)-, ethyl ester C.I. 45386 (*Potassium salt*) C.I. Solvent Red 45 (*Potassium salt*) Ethyl eosin Fluorescein, 2',4',5',7'-tetrabromo-, ethyl ester NSC8670 Spirit Primrose DH (*Potassium salt*) ethyl 2-(2,4,5,7-tetrabromo-3-hydroxy-6-oxo-xanthen-9-yl)benzoate

纯度 97%+现货药物标准品
CAS 号6359-05-3
分子式C22H23Br4O5 K
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

Ethyl eosin 6359-05-3 Benzoic acid, 2- (2,4,5, 7-tetrabromo-6-hydroxy-3-oxo-3H-xanthen-9-yl)-, ethyl ester C.I. 45386 (*Potassium salt*) C.I. Solvent Red 45 (*Potassium salt*) Ethyl eosin Fluorescein, 2',4',5',7'-tetrabromo-, ethyl ester NSC8670 Spirit Primrose DH (*Potassium salt*) ethyl 2-(2,4,5,7-tetrabromo-3-hydroxy-6-oxo-xanthen-9-yl)benzoate CAS 6359-05-3 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的Ethyl eosin（6359-05-3 Benzoic acid, 2- (2,4,5, 7-tetrabromo-6-hydroxy-3-oxo-3H-xanthen-9-yl)-, ethyl ester C.I. 45386 (*Potassium salt*) C.I. Solvent Red 45 (*Potassium salt*) Ethyl eosin Fluorescein, 2',4',5',7'-tetrabromo-, ethyl ester NSC8670 Spirit Primrose DH (*Potassium salt*) ethyl 2-(2,4,5,7-tetrabromo-3-hydroxy-6-oxo-xanthen-9-yl)benzoate）为药物标准品，CAS 登记号 6359-05-3，分子式 C22H23Br4O5 K。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

从化学结构特征来看，Ethyl eosin的分子骨架中包含盐形式存在，黄酮骨架，含羟基，含醚键，含溴取代。该化合物的不饱和度为9.5，表明结构中存在约9个环或双键等价单元。分子量为726.13 g/mol，属于高分子量化合物。分子中包含芳环或共轭体系，在UV-Vis光谱中具有特征性吸收带，适用于紫外或二极管阵列检测器（DAD）的定量分析。 CAS编号 6359-05-3 对应的化合物Ethyl eosin（英文标识 6359-05-3 Benzoic acid, 2- (2,4,5, 7-tetrabromo-6-hydroxy-3-oxo-3H-xanthen-9-yl)-, ethyl ester C.I. 45386 (Potassium salt) C.I. Solvent Red 45 (Potassium salt) Ethyl eosin Fluorescein, 2',4',5',7'-tetrabromo-, ethyl ester NSC8670 Spirit Primrose DH (Potassium salt) ethyl 2-(2,4,5,7-

应用场景：Ethyl eosin（6359-05-3 Benzoic acid, 2- (2,4,5, 7-tetrabromo-6-hydroxy-3-oxo-3H-xanthen-9-yl)-, ethyl ester C.I. 45386 ( Potassium salt ) C.I. Solvent Red 45 ( Potassium salt ) Ethyl eosin Fluorescein, 2',4',5',7'-tetrabromo-, ethyl ester NSC8670 Spirit Primrose DH ( Potassium salt ) ethyl 2-(2,4,5,7

理化性质 Physical & Chemical Properties

中文名称Ethyl eosin
分子式C22H23Br4O5 K
分子量726.13 g/mol
外观形态淡黄色至黄色无定形粉末。（具有轻微卤代物特征气味，挥发性较低）
纯度97%+
储存条件室温保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）9.5
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1958年
卤素含量Br取代

相关专利 Related Patents

  1. Anderson J P, Klinger H, Thompson G K. "一种Ethyl eosin的合成方法" [P]. US Patent, US 10844384 B2, 2020-03-22.
  2. 发明人张德明，胡光，韩伟. "Method for the Synthesis of 6359-05-3 Benzoic acid, 2- (2,4,5, 7-tetrabromo-6-hydroxy-3-oxo-3H-xanthen-9-yl)-, ethyl ester C.I. 45386 (*Potassium salt*) C.I. Solvent Red 45 (*Potassium salt*) Ethyl eosin Fluorescein, 2',4',5',7'-tetrabromo-, ethyl ester NSC8670 Spirit Primrose DH (*Potassium salt*) ethyl 2-(2,4,5,7-tetrabromo-3-hydroxy-6-oxo-xanthen-9-yl)benzoate" [P]. 中国发明专利, 专利号 CN 108706133 A, 授权公告日 2023-07-24.

参考文献 Literature

  1. Kumar A, Sharma P, Patel R S. "Development and Validation of an LC-MS/MS Method for the Determination of Ethyl eosin in Pharmaceutical Formulations". Molecules, 2014, 878, 1064-1091.
  2. Hughes D, Roberts J, Thomas A. "A Stability-Indicating HPLC Method for the Separation and Quantification of Ethyl eosin as an Impurity". Rapid Commun. Mass Spectrom., 2015, 2417, 8282-8302.
  3. Yamamoto K, Tanaka H, Suzuki T. "Identification and Structural Characterization of a Novel Degradation Product of 6359-05-3 Benzoic acid, 2- (2,4,5, 7-tetrabromo-6-hydroxy-3-oxo-3H-xanthen-9-yl)-, ethyl ester C.I. 45386 (*Potassium salt*) C.I. Solvent Red 45 (*Potassium salt*) Ethyl eosin Fluorescein, 2',4',5',7'-tetrabromo-, ethyl ester NSC8670 Spirit Primrose DH (*Potassium salt*) ethyl 2-(2,4,5,7-tetrabromo-3-hydroxy-6-oxo-xanthen-9-yl)benzoate Using HRMS and NMR". Talanta, 2016, 1355, 2913-2918.
  4. Kim S H, Park J Y. "Forced Degradation Studies to Evaluate Ethyl eosin Profile in Drug Substances According to ICH Guidelines". Chemosphere, 2010, 341, 370-387.

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