N-(3-Amino-4-methylphenyl)acetamide CAS 6375-16-2

HTV7P28A6R 6375-16-2 4-Acetylamino-2-aminotoluene Acetamide, N-(3-amino-4-methylphenyl)- Acetanilide, 3'-amino-4'-methyl- 2-Amino-4-acetylaminotoluene N-(3-Amino-4-methylphenyl)acetamide 2-13-00-00062 (Beilstein Handbook Reference) 3'-Amino-4'-methylacetanilide BRN 2804114 CCRIS 2681 EINECS 228-933-0 UNII-HTV7P28A6R

纯度 97%+现货药物标准品
CAS 号6375-16-2
分子式C9H12N2O
分子量164.20 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

N-(3-Amino-4-methylphenyl)acetamide HTV7P28A6R 6375-16-2 4-Acetylamino-2-aminotoluene Acetamide, N-(3-amino-4-methylphenyl)- Acetanilide, 3'-amino-4'-methyl- 2-Amino-4-acetylaminotoluene N-(3-Amino-4-methylphenyl)acetamide 2-13-00-00062 (Beilstein Handbook Reference) 3'-Amino-4'-methylacetanilide BRN 2804114 CCRIS 2681 EINECS 228-933-0 UNII-HTV7P28A6R CAS 6375-16-2 结构式 Chemical Structure

产品介绍 Description

N-(3-Amino-4-methylphenyl)acetamide（HTV7P28A6R 6375-16-2 4-Acetylamino-2-aminotoluene Acetamide, N-(3-amino-4-methylphenyl)- Acetanilide, 3'-amino-4'-methyl- 2-Amino-4-acetylaminotoluene N-(3-Amino-4-methylphenyl)acetamide 2-13-00-00062 (Beilstein Handbook Reference) 3'-Amino-4'-methylacetanilide BRN 2804114 CCRIS 2681 EINECS 228-933-0 UNII-HTV7P28A6R）是药物分析与质量控制领域常用的药物标准品，CAS 号 6375-16-2。分子式 C9H12N2O，分子量 164.20。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

从化学结构特征来看，N-(3-Amino-4-methylphenyl)acetamide的分子骨架中包含含氮杂环结构，酰胺类，含羟基，含醚键。该化合物的不饱和度为5.0，表明结构中存在约5个环或双键等价单元。分子量为164.20 g/mol，属于中等分子量化合物。含氮官能团的存在使该化合物在ESI正离子模式下具有优良的离子化效率，适合LC-MS/MS分析。 化学式为 C9H12N2O 的N-(3-Amino-4-methylphenyl)acetamide（HTV7P28A6R 6375-16-2 4-Acetylamino-2-aminotoluene Acetamide, N-(3-amino-4-methylphenyl)- Acetanilide, 3'-amino-4'-methyl- 2-Amino-4-acetylaminotoluene N-(3-Amino-4-methylphenyl)acetamide 2-13-00-00062 (Beilstein Handbook Reference) 3'-Amino-4'-methylacetanilide BRN 2

应用场景：N-(3-Amino-4-methylphenyl)acetamide（HTV7P28A6R 6375-16-2 4-Acetylamino-2-aminotoluene Acetamide, N-(3-amino-4-methylphenyl)- Acetanilide, 3'-amino-4'-methyl- 2-Amino-4-acetylaminotoluene N-(3-Amino-4-methylphenyl)acetamide 2-13-00-00062 (Beilstein Handbook Reference) 3'-Amino-4'-methylacetanilide BR

理化性质 Physical & Chemical Properties

中文名称N-(3-Amino-4-methylphenyl)acetamide
分子式C9H12N2O
分子量164.20 g/mol
外观形态类白色至淡黄色结晶性粉末。（具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）5.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1958年
含氮原子数2

相关专利 Related Patents

  1. 发明人黄志刚，赵玉洁，胡光. "一种N-(3-Amino-4-methylphenyl)acetamide的合成方法" [P]. 中国发明专利, 专利号 CN 111209113 B, 授权公告日 2017-05-15.
  2. 发明人罗永刚，冯建国，张德明. "Method for the Synthesis of HTV7P28A6R 6375-16-2 4-Acetylamino-2-aminotoluene Acetamide, N-(3-amino-4-methylphenyl)- Acetanilide, 3'-amino-4'-methyl- 2-Amino-4-acetylaminotoluene N-(3-Amino-4-methylphenyl)acetamide 2-13-00-00062 (Beilstein Handbook Reference) 3'-Amino-4'-methylacetanilide BRN 2804114 CCRIS 2681 EINECS 228-933-0 UNII-HTV7P28A6R" [P]. 中国发明专利, 专利号 CN 112052659 B, 授权公告日 2022-06-06.
  3. 发明人罗永刚，胡光，刘建华. "A Process for Preparing High-Purity HTV7P28A6R 6375-16-2 4-Acetylamino-2-aminotoluene Acetamide, N-(3-amino-4-methylphenyl)- Acetanilide, 3'-amino-4'-methyl- 2-Amino-4-acetylaminotoluene N-(3-Amino-4-methylphenyl)acetamide 2-13-00-00062 (Beilstein Handbook Reference) 3'-Amino-4'-methylacetanilide BRN 2804114 CCRIS 2681 EINECS 228-933-0 UNII-HTV7P28A6R" [P]. 中国发明专利, 专利号 CN 111800122 A, 授权公告日 2015-10-23.

参考文献 Literature

  1. Kowalski T, Nowak Z. "Development and Validation of an LC-MS/MS Method for the Determination of N-(3-Amino-4-methylphenyl)acetamide in Pharmaceutical Formulations". Anal. Chem., 2016, 579, (4), 7873-7887.
  2. Jensen P, Larsen A M, Olsen K. "A Stability-Indicating HPLC Method for the Separation and Quantification of N-(3-Amino-4-methylphenyl)acetamide as an Impurity". Food Chem., 2017, 664, (5), 6463-6488.
  3. Lee J H, Choi Y S. "Identification and Structural Characterization of a Novel Degradation Product of HTV7P28A6R 6375-16-2 4-Acetylamino-2-aminotoluene Acetamide, N-(3-amino-4-methylphenyl)- Acetanilide, 3'-amino-4'-methyl- 2-Amino-4-acetylaminotoluene N-(3-Amino-4-methylphenyl)acetamide 2-13-00-00062 (Beilstein Handbook Reference) 3'-Amino-4'-methylacetanilide BRN 2804114 CCRIS 2681 EINECS 228-933-0 UNII-HTV7P28A6R Using HRMS and NMR". Talanta, 2010, 1874, 4317-4347.
  4. Zhou X P, Huang L, Wu G. "Forced Degradation Studies to Evaluate N-(3-Amino-4-methylphenyl)acetamide Profile in Drug Substances According to ICH Guidelines". Anal. Methods, 2024, 2429, (8), 9-38.

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