18:1（Δ9-顺式）PG CAS 67254-28-8

T40U11PG20 67254-28-8 1,2-Dioleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)), sodium salt UNII-T40U11PG20 1,2-Di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-rac-glycerol) (Sodium salt) 1,2-Dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol), sodium salt 9-Octadecenoic acid (9Z)-, 1,1'-(1-((((2,3-dihydroxypropoxy)hydroxyphosphinyl)oxy)methyl)-1,2-ethanediyl) ester, sodium salt (1:1) DOPG Na, l- DOPG Na, r- DOPG-Na, l- DOPG-Na, r-

纯度 97%+现货药物标准品
CAS 号67254-28-8
分子式C42H78O10P Na
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

18:1（Δ9-顺式）PG T40U11PG20 67254-28-8 1,2-Dioleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)), sodium salt UNII-T40U11PG20 1,2-Di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-rac-glycerol) (Sodium salt) 1,2-Dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol), sodium salt 9-Octadecenoic acid (9Z)-, 1,1'-(1-((((2,3-dihydroxypropoxy)hydroxyphosphinyl)oxy)methyl)-1,2-ethanediyl) ester, sodium salt (1:1) DOPG Na, l- DOPG Na, r- DOPG-Na, l- DOPG-Na, r- CAS 67254-28-8 结构式 Chemical Structure

产品介绍 Description

18:1（Δ9-顺式）PG（T40U11PG20 67254-28-8 1,2-Dioleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)), sodium salt UNII-T40U11PG20 1,2-Di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-rac-glycerol) (Sodium salt) 1,2-Dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol), sodium salt 9-Octadecenoic acid (9Z)-, 1,1'-(1-((((2,3-dihydroxypropoxy)hydroxyphosphinyl)oxy)methyl)-1,2-ethanediyl) ester, sodium salt (1:1) DOPG Na, l- DOPG Na, r- DOPG-Na, l- DOPG-Na, r-，CAS 号 67254-28-8）是 CATO 佳途自主生产的药物标准品，分子式 C42H78O10P Na。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

18:1（Δ9-顺式）PG的产生途径与其化学式中含磷酸酯基，羧酸类，含羟基，含醚键密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 18:1（Δ9-顺式）PG（T40U11PG20 67254-28-8 1,2-Dioleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)), sodium salt UNII-T40U11PG20 1,2-Di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-rac-glycerol) (Sodium salt) 1,2-Dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol), sodium salt 9-Octadecenoic acid (9Z)-, 1,1'-(1-((((2,3-dihydroxypropoxy)hydroxyphosphinyl)oxy)methyl)-1,2-ethanediyl) ester, sodium salt (1:1) DOPG Na, l- DOPG Na, r- DOPG-N

应用场景：18:1（Δ9-顺式）PG（T40U11PG20 67254-28-8 1,2-Dioleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)), sodium salt UNII-T40U11PG20 1,2-Di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-rac-glycerol) (Sodium salt) 1,2-Dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol), sodium salt 9-Octadecenoic acid (9Z)-, 1,1'-(1-((((

理化性质 Physical & Chemical Properties

中文名称18:1（Δ9-顺式）PG
分子式C42H78O10P Na
分子量797.04 g/mol
外观形态类白色至淡黄色无定形粉末
纯度97%+
储存条件室温保存，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性空气中长期暴露可能发生缓慢氧化
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）4.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1976年

相关专利 Related Patents

  1. Roberts E F, Thompson G K, O'Brien P Q. "一种18:1（Δ9-顺式）PG的合成方法" [P]. US Patent, US 10781452 B2, 2018-02-19.
  2. 发明人张德明，刘建华，冯建国. "Method for the Synthesis of T40U11PG20 67254-28-8 1,2-Dioleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)), sodium salt UNII-T40U11PG20 1,2-Di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-rac-glycerol) (Sodium salt) 1,2-Dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol), sodium salt 9-Octadecenoic acid (9Z)-, 1,1'-(1-((((2,3-dihydroxypropoxy)hydroxyphosphinyl)oxy)methyl)-1,2-ethanediyl) ester, sodium salt (1:1) DOPG Na, l- DOPG Na, r- DOPG-Na, l- DOPG-Na, r-" [P]. 中国发明专利, 专利号 CN 108799121 A, 授权公告日 2018-05-07.
  3. Jørgensen K, Johansson L, Sørensen M. "A Process for Preparing High-Purity T40U11PG20 67254-28-8 1,2-Dioleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)), sodium salt UNII-T40U11PG20 1,2-Di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-rac-glycerol) (Sodium salt) 1,2-Dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol), sodium salt 9-Octadecenoic acid (9Z)-, 1,1'-(1-((((2,3-dihydroxypropoxy)hydroxyphosphinyl)oxy)methyl)-1,2-ethanediyl) ester, sodium salt (1:1) DOPG Na, l- DOPG Na, r- DOPG-Na, l- DOPG-Na, r-" [P]. European Patent, EP 3579184 A1, 2018-02-14.

参考文献 Literature

  1. Chen X Y, Liu M, Zhao W Q. "Development and Validation of an LC-MS/MS Method for the Determination of 18:1（Δ9-顺式）PG in Pharmaceutical Formulations". Talanta, 2014, 2253, (3), 7591-7609.
  2. Yamamoto K, Tanaka H, Suzuki T. "A Stability-Indicating HPLC Method for the Separation and Quantification of 18:1（Δ9-顺式）PG as an Impurity". Sci. Total Environ., 2013, 1131, 9564-9584.
  3. Kim S H, Park J Y. "Identification and Structural Characterization of a Novel Degradation Product of T40U11PG20 67254-28-8 1,2-Dioleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)), sodium salt UNII-T40U11PG20 1,2-Di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-rac-glycerol) (Sodium salt) 1,2-Dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol), sodium salt 9-Octadecenoic acid (9Z)-, 1,1'-(1-((((2,3-dihydroxypropoxy)hydroxyphosphinyl)oxy)methyl)-1,2-ethanediyl) ester, sodium salt (1:1) DOPG Na, l- DOPG Na, r- DOPG-Na, l- DOPG-Na, r- Using HRMS and NMR". Anal. Chim. Acta, 2013, 1848, (11), 8100-8124.

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...